| Full name: TIA1 cytotoxic granule associated RNA binding protein like 1 | Alias Symbol: TIAR | ||
| Type: protein-coding gene | Cytoband: 10q26.11 | ||
| Entrez ID: 7073 | HGNC ID: HGNC:11804 | Ensembl Gene: ENSG00000151923 | OMIM ID: 603413 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of TIAL1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TIAL1 | 7073 | 202406_s_at | 0.0112 | 0.9822 | |
| GSE20347 | TIAL1 | 7073 | 202406_s_at | 0.0692 | 0.5801 | |
| GSE23400 | TIAL1 | 7073 | 202406_s_at | 0.2149 | 0.0013 | |
| GSE26886 | TIAL1 | 7073 | 202406_s_at | -0.1872 | 0.1810 | |
| GSE29001 | TIAL1 | 7073 | 202406_s_at | 0.1436 | 0.4777 | |
| GSE38129 | TIAL1 | 7073 | 202406_s_at | 0.2330 | 0.0624 | |
| GSE45670 | TIAL1 | 7073 | 202406_s_at | 0.1014 | 0.2516 | |
| GSE53622 | TIAL1 | 7073 | 63030 | -0.0215 | 0.6494 | |
| GSE53624 | TIAL1 | 7073 | 63030 | 0.0979 | 0.0288 | |
| GSE63941 | TIAL1 | 7073 | 202406_s_at | -0.5724 | 0.1286 | |
| GSE77861 | TIAL1 | 7073 | 202406_s_at | 0.0093 | 0.9647 | |
| GSE97050 | TIAL1 | 7073 | A_23_P161488 | 0.2804 | 0.3304 | |
| SRP007169 | TIAL1 | 7073 | RNAseq | -0.0669 | 0.8520 | |
| SRP008496 | TIAL1 | 7073 | RNAseq | -0.0629 | 0.7788 | |
| SRP064894 | TIAL1 | 7073 | RNAseq | -0.1535 | 0.1593 | |
| SRP133303 | TIAL1 | 7073 | RNAseq | 0.0872 | 0.3717 | |
| SRP159526 | TIAL1 | 7073 | RNAseq | -0.1629 | 0.3863 | |
| SRP193095 | TIAL1 | 7073 | RNAseq | -0.0622 | 0.3591 | |
| SRP219564 | TIAL1 | 7073 | RNAseq | -0.0092 | 0.9738 | |
| TCGA | TIAL1 | 7073 | RNAseq | 0.0071 | 0.8771 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by TIAL1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TIAL1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TIAL1 | 7073 | 2 | 8 | 20 | |
| GSE20123 | TIAL1 | 7073 | 2 | 8 | 20 | |
| GSE43470 | TIAL1 | 7073 | 0 | 9 | 34 | |
| GSE46452 | TIAL1 | 7073 | 0 | 11 | 48 | |
| GSE47630 | TIAL1 | 7073 | 2 | 14 | 24 | |
| GSE54993 | TIAL1 | 7073 | 8 | 0 | 62 | |
| GSE54994 | TIAL1 | 7073 | 1 | 9 | 43 | |
| GSE60625 | TIAL1 | 7073 | 0 | 0 | 11 | |
| GSE74703 | TIAL1 | 7073 | 0 | 6 | 30 | |
| GSE74704 | TIAL1 | 7073 | 1 | 3 | 16 | |
| TCGA | TIAL1 | 7073 | 5 | 28 | 63 |
Total number of gains: 21; Total number of losses: 96; Total Number of normals: 371.
Somatic mutations of TIAL1:
Generating mutation plots.
Highly correlated genes for TIAL1:
Showing top 20/189 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TIAL1 | MRPL13 | 0.763772 | 3 | 0 | 3 |
| TIAL1 | FRMD6 | 0.74979 | 3 | 0 | 3 |
| TIAL1 | HCFC2 | 0.746485 | 3 | 0 | 3 |
| TIAL1 | ZMPSTE24 | 0.726927 | 3 | 0 | 3 |
| TIAL1 | FAM160B1 | 0.724282 | 3 | 0 | 3 |
| TIAL1 | COX16 | 0.70689 | 3 | 0 | 3 |
| TIAL1 | MBNL3 | 0.702832 | 3 | 0 | 3 |
| TIAL1 | SETD4 | 0.699422 | 3 | 0 | 3 |
| TIAL1 | USP9Y | 0.696459 | 3 | 0 | 3 |
| TIAL1 | PAQR7 | 0.694179 | 3 | 0 | 3 |
| TIAL1 | RASA2 | 0.68716 | 5 | 0 | 4 |
| TIAL1 | ZNF266 | 0.684153 | 4 | 0 | 3 |
| TIAL1 | ASNSD1 | 0.682549 | 3 | 0 | 3 |
| TIAL1 | LSM12 | 0.6821 | 3 | 0 | 3 |
| TIAL1 | COIL | 0.680155 | 4 | 0 | 4 |
| TIAL1 | HECTD3 | 0.678878 | 3 | 0 | 3 |
| TIAL1 | INTU | 0.664804 | 3 | 0 | 3 |
| TIAL1 | ARL16 | 0.664345 | 3 | 0 | 3 |
| TIAL1 | SCYL2 | 0.662216 | 3 | 0 | 3 |
| TIAL1 | ITGA2 | 0.661097 | 4 | 0 | 4 |
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