| Full name: translocase of inner mitochondrial membrane 8 homolog B | Alias Symbol: TIM8B|DDP2|FLJ21744|MGC102866|MGC117373 | ||
| Type: protein-coding gene | Cytoband: 11q23.1 | ||
| Entrez ID: 26521 | HGNC ID: HGNC:11818 | Ensembl Gene: ENSG00000150779 | OMIM ID: 606659 |
| Drug and gene relationship at DGIdb | |||
Expression of TIMM8B:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TIMM8B | 26521 | 218357_s_at | -0.1527 | 0.6394 | |
| GSE20347 | TIMM8B | 26521 | 218357_s_at | -0.5508 | 0.0001 | |
| GSE23400 | TIMM8B | 26521 | 218357_s_at | -0.4073 | 0.0000 | |
| GSE26886 | TIMM8B | 26521 | 218357_s_at | -0.4795 | 0.0016 | |
| GSE29001 | TIMM8B | 26521 | 218357_s_at | -0.9422 | 0.0012 | |
| GSE38129 | TIMM8B | 26521 | 218357_s_at | -0.3902 | 0.0220 | |
| GSE45670 | TIMM8B | 26521 | 218357_s_at | -0.2912 | 0.0789 | |
| GSE53622 | TIMM8B | 26521 | 17500 | -0.8097 | 0.0000 | |
| GSE53624 | TIMM8B | 26521 | 17500 | -0.6660 | 0.0000 | |
| GSE63941 | TIMM8B | 26521 | 218357_s_at | -0.2679 | 0.4843 | |
| GSE77861 | TIMM8B | 26521 | 218357_s_at | -0.6848 | 0.0683 | |
| GSE97050 | TIMM8B | 26521 | A_23_P98382 | -0.3856 | 0.2583 | |
| SRP007169 | TIMM8B | 26521 | RNAseq | -1.5087 | 0.0001 | |
| SRP008496 | TIMM8B | 26521 | RNAseq | -1.2420 | 0.0000 | |
| SRP064894 | TIMM8B | 26521 | RNAseq | -0.7366 | 0.0217 | |
| SRP133303 | TIMM8B | 26521 | RNAseq | -0.8763 | 0.0000 | |
| SRP159526 | TIMM8B | 26521 | RNAseq | -0.8778 | 0.0085 | |
| SRP193095 | TIMM8B | 26521 | RNAseq | -1.6466 | 0.0000 | |
| SRP219564 | TIMM8B | 26521 | RNAseq | -1.2182 | 0.0015 | |
| TCGA | TIMM8B | 26521 | RNAseq | 0.0911 | 0.2952 |
Upregulated datasets: 0; Downregulated datasets: 4.
Survival by TIMM8B expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TIMM8B:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TIMM8B | 26521 | 0 | 12 | 18 | |
| GSE20123 | TIMM8B | 26521 | 0 | 12 | 18 | |
| GSE43470 | TIMM8B | 26521 | 2 | 6 | 35 | |
| GSE46452 | TIMM8B | 26521 | 3 | 26 | 30 | |
| GSE47630 | TIMM8B | 26521 | 2 | 19 | 19 | |
| GSE54993 | TIMM8B | 26521 | 10 | 0 | 60 | |
| GSE54994 | TIMM8B | 26521 | 5 | 19 | 29 | |
| GSE60625 | TIMM8B | 26521 | 0 | 3 | 8 | |
| GSE74703 | TIMM8B | 26521 | 1 | 4 | 31 | |
| GSE74704 | TIMM8B | 26521 | 0 | 8 | 12 | |
| TCGA | TIMM8B | 26521 | 7 | 48 | 41 |
Total number of gains: 30; Total number of losses: 157; Total Number of normals: 301.
Somatic mutations of TIMM8B:
Generating mutation plots.
Highly correlated genes for TIMM8B:
Showing top 20/846 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TIMM8B | NCCRP1 | 0.768784 | 3 | 0 | 3 |
| TIMM8B | OTOP3 | 0.75933 | 3 | 0 | 3 |
| TIMM8B | FAM163B | 0.749957 | 3 | 0 | 3 |
| TIMM8B | KPRP | 0.747385 | 3 | 0 | 3 |
| TIMM8B | KRTAP20-1 | 0.745999 | 3 | 0 | 3 |
| TIMM8B | MUC22 | 0.73905 | 3 | 0 | 3 |
| TIMM8B | MORN3 | 0.733461 | 4 | 0 | 4 |
| TIMM8B | GGT6 | 0.723683 | 6 | 0 | 6 |
| TIMM8B | MFSD2B | 0.719065 | 3 | 0 | 3 |
| TIMM8B | ARHGAP32 | 0.707341 | 10 | 0 | 10 |
| TIMM8B | TMPRSS11A | 0.706191 | 3 | 0 | 3 |
| TIMM8B | C3orf20 | 0.7057 | 3 | 0 | 3 |
| TIMM8B | VSIG10L | 0.701806 | 6 | 0 | 6 |
| TIMM8B | LYNX1 | 0.699992 | 6 | 0 | 6 |
| TIMM8B | AIF1L | 0.697966 | 7 | 0 | 7 |
| TIMM8B | TPRN | 0.697818 | 6 | 0 | 6 |
| TIMM8B | TGM3 | 0.697477 | 10 | 0 | 9 |
| TIMM8B | GPX6 | 0.696658 | 3 | 0 | 3 |
| TIMM8B | ULK3 | 0.695427 | 6 | 0 | 6 |
| TIMM8B | PRSS27 | 0.694494 | 7 | 0 | 7 |
For details and further investigation, click here
