| Full name: Rho GTPase activating protein 32 | Alias Symbol: GRIT|KIAA0712|MGC1892|RICS|GC-GAP | ||
| Type: protein-coding gene | Cytoband: 11q24.3 | ||
| Entrez ID: 9743 | HGNC ID: HGNC:17399 | Ensembl Gene: ENSG00000134909 | OMIM ID: 608541 |
| Drug and gene relationship at DGIdb | |||
Expression of ARHGAP32:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ARHGAP32 | 9743 | 203431_s_at | -0.5712 | 0.5624 | |
| GSE20347 | ARHGAP32 | 9743 | 203431_s_at | -1.6858 | 0.0000 | |
| GSE23400 | ARHGAP32 | 9743 | 203431_s_at | -1.2625 | 0.0000 | |
| GSE26886 | ARHGAP32 | 9743 | 203431_s_at | -2.2826 | 0.0000 | |
| GSE29001 | ARHGAP32 | 9743 | 203431_s_at | -1.5644 | 0.0007 | |
| GSE38129 | ARHGAP32 | 9743 | 203431_s_at | -1.2094 | 0.0000 | |
| GSE45670 | ARHGAP32 | 9743 | 203431_s_at | -0.2292 | 0.4270 | |
| GSE53622 | ARHGAP32 | 9743 | 3327 | -1.2073 | 0.0000 | |
| GSE53624 | ARHGAP32 | 9743 | 37985 | -1.5826 | 0.0000 | |
| GSE63941 | ARHGAP32 | 9743 | 203431_s_at | -0.6268 | 0.2517 | |
| GSE77861 | ARHGAP32 | 9743 | 203431_s_at | -0.8785 | 0.0426 | |
| GSE97050 | ARHGAP32 | 9743 | A_24_P42436 | -0.0152 | 0.9858 | |
| SRP007169 | ARHGAP32 | 9743 | RNAseq | -1.9315 | 0.0000 | |
| SRP008496 | ARHGAP32 | 9743 | RNAseq | -1.7369 | 0.0000 | |
| SRP064894 | ARHGAP32 | 9743 | RNAseq | -2.0443 | 0.0000 | |
| SRP133303 | ARHGAP32 | 9743 | RNAseq | -1.6085 | 0.0000 | |
| SRP159526 | ARHGAP32 | 9743 | RNAseq | -2.4350 | 0.0000 | |
| SRP193095 | ARHGAP32 | 9743 | RNAseq | -1.8188 | 0.0000 | |
| SRP219564 | ARHGAP32 | 9743 | RNAseq | -2.1964 | 0.0012 | |
| TCGA | ARHGAP32 | 9743 | RNAseq | 0.0025 | 0.9757 |
Upregulated datasets: 0; Downregulated datasets: 14.
Survival by ARHGAP32 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ARHGAP32:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ARHGAP32 | 9743 | 0 | 13 | 17 | |
| GSE20123 | ARHGAP32 | 9743 | 0 | 13 | 17 | |
| GSE43470 | ARHGAP32 | 9743 | 2 | 7 | 34 | |
| GSE46452 | ARHGAP32 | 9743 | 3 | 26 | 30 | |
| GSE47630 | ARHGAP32 | 9743 | 2 | 19 | 19 | |
| GSE54993 | ARHGAP32 | 9743 | 10 | 0 | 60 | |
| GSE54994 | ARHGAP32 | 9743 | 5 | 19 | 29 | |
| GSE60625 | ARHGAP32 | 9743 | 0 | 3 | 8 | |
| GSE74703 | ARHGAP32 | 9743 | 1 | 5 | 30 | |
| GSE74704 | ARHGAP32 | 9743 | 0 | 9 | 11 | |
| TCGA | ARHGAP32 | 9743 | 6 | 50 | 40 |
Total number of gains: 29; Total number of losses: 164; Total Number of normals: 295.
Somatic mutations of ARHGAP32:
Generating mutation plots.
Highly correlated genes for ARHGAP32:
Showing top 20/1606 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ARHGAP32 | ZDHHC13 | 0.855663 | 11 | 0 | 11 |
| ARHGAP32 | CTNND1 | 0.829739 | 3 | 0 | 3 |
| ARHGAP32 | ARHGAP27 | 0.829534 | 7 | 0 | 7 |
| ARHGAP32 | EVPL | 0.825404 | 11 | 0 | 11 |
| ARHGAP32 | RBM47 | 0.822812 | 11 | 0 | 11 |
| ARHGAP32 | EPS8L1 | 0.813701 | 11 | 0 | 11 |
| ARHGAP32 | DUOX1 | 0.810801 | 11 | 0 | 11 |
| ARHGAP32 | GRHL1 | 0.809593 | 7 | 0 | 7 |
| ARHGAP32 | EPS8L2 | 0.809045 | 11 | 0 | 11 |
| ARHGAP32 | MPZL2 | 0.807045 | 11 | 0 | 11 |
| ARHGAP32 | CHP1 | 0.806205 | 10 | 0 | 10 |
| ARHGAP32 | MPZL3 | 0.804884 | 7 | 0 | 7 |
| ARHGAP32 | NBEAL2 | 0.803679 | 11 | 0 | 11 |
| ARHGAP32 | UPK3B | 0.80129 | 3 | 0 | 3 |
| ARHGAP32 | NIPAL1 | 0.799818 | 3 | 0 | 3 |
| ARHGAP32 | EXPH5 | 0.796209 | 11 | 0 | 10 |
| ARHGAP32 | ARAP2 | 0.794925 | 3 | 0 | 3 |
| ARHGAP32 | S100A16 | 0.794574 | 7 | 0 | 7 |
| ARHGAP32 | MACC1 | 0.794383 | 7 | 0 | 7 |
| ARHGAP32 | GRHL3 | 0.794062 | 7 | 0 | 7 |
For details and further investigation, click here
