| Full name: tight junction associated protein 1 | Alias Symbol: PILT | ||
| Type: protein-coding gene | Cytoband: 6p21.1 | ||
| Entrez ID: 93643 | HGNC ID: HGNC:17949 | Ensembl Gene: ENSG00000137221 | OMIM ID: 612658 |
| Drug and gene relationship at DGIdb | |||
Expression of TJAP1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TJAP1 | 93643 | 47608_at | 0.6080 | 0.1239 | |
| GSE20347 | TJAP1 | 93643 | 47608_at | 0.6978 | 0.0000 | |
| GSE23400 | TJAP1 | 93643 | 47608_at | 0.3985 | 0.0000 | |
| GSE26886 | TJAP1 | 93643 | 47608_at | 1.2267 | 0.0000 | |
| GSE29001 | TJAP1 | 93643 | 47608_at | 0.4254 | 0.1512 | |
| GSE38129 | TJAP1 | 93643 | 47608_at | 0.4925 | 0.0001 | |
| GSE45670 | TJAP1 | 93643 | 47608_at | 0.2572 | 0.1299 | |
| GSE53622 | TJAP1 | 93643 | 35063 | 0.5994 | 0.0000 | |
| GSE53624 | TJAP1 | 93643 | 42602 | 0.7896 | 0.0000 | |
| GSE63941 | TJAP1 | 93643 | 47608_at | 0.5658 | 0.0124 | |
| GSE77861 | TJAP1 | 93643 | 221857_s_at | 0.1793 | 0.1755 | |
| GSE97050 | TJAP1 | 93643 | A_23_P81811 | 0.3664 | 0.2151 | |
| SRP007169 | TJAP1 | 93643 | RNAseq | 0.9399 | 0.0386 | |
| SRP008496 | TJAP1 | 93643 | RNAseq | 1.3864 | 0.0000 | |
| SRP064894 | TJAP1 | 93643 | RNAseq | 0.7050 | 0.0000 | |
| SRP133303 | TJAP1 | 93643 | RNAseq | 0.5329 | 0.0000 | |
| SRP159526 | TJAP1 | 93643 | RNAseq | 0.6866 | 0.0192 | |
| SRP193095 | TJAP1 | 93643 | RNAseq | 0.9093 | 0.0000 | |
| SRP219564 | TJAP1 | 93643 | RNAseq | 0.5275 | 0.0724 | |
| TCGA | TJAP1 | 93643 | RNAseq | 0.0070 | 0.9032 |
Upregulated datasets: 2; Downregulated datasets: 0.
Survival by TJAP1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TJAP1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TJAP1 | 93643 | 7 | 0 | 23 | |
| GSE20123 | TJAP1 | 93643 | 7 | 0 | 23 | |
| GSE43470 | TJAP1 | 93643 | 6 | 0 | 37 | |
| GSE46452 | TJAP1 | 93643 | 2 | 9 | 48 | |
| GSE47630 | TJAP1 | 93643 | 8 | 4 | 28 | |
| GSE54993 | TJAP1 | 93643 | 3 | 2 | 65 | |
| GSE54994 | TJAP1 | 93643 | 11 | 4 | 38 | |
| GSE60625 | TJAP1 | 93643 | 0 | 1 | 10 | |
| GSE74703 | TJAP1 | 93643 | 6 | 0 | 30 | |
| GSE74704 | TJAP1 | 93643 | 3 | 0 | 17 | |
| TCGA | TJAP1 | 93643 | 20 | 12 | 64 |
Total number of gains: 73; Total number of losses: 32; Total Number of normals: 383.
Somatic mutations of TJAP1:
Generating mutation plots.
Highly correlated genes for TJAP1:
Showing top 20/611 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TJAP1 | PNMA6A | 0.6968 | 3 | 0 | 3 |
| TJAP1 | CNPY3 | 0.692399 | 9 | 0 | 8 |
| TJAP1 | SERPINH1 | 0.690567 | 11 | 0 | 10 |
| TJAP1 | LINC00674 | 0.67984 | 3 | 0 | 3 |
| TJAP1 | ZNF205 | 0.675 | 4 | 0 | 4 |
| TJAP1 | HOXC9 | 0.669552 | 5 | 0 | 4 |
| TJAP1 | SIX4 | 0.6681 | 6 | 0 | 4 |
| TJAP1 | FNDC3B | 0.666032 | 10 | 0 | 9 |
| TJAP1 | CHRM3 | 0.66511 | 4 | 0 | 4 |
| TJAP1 | YEATS2 | 0.664143 | 10 | 0 | 8 |
| TJAP1 | IPO9 | 0.663364 | 9 | 0 | 9 |
| TJAP1 | MFAP2 | 0.660721 | 10 | 0 | 10 |
| TJAP1 | ZNF232 | 0.660022 | 10 | 0 | 8 |
| TJAP1 | ZNF618 | 0.658839 | 4 | 0 | 4 |
| TJAP1 | FAM24B | 0.656407 | 3 | 0 | 3 |
| TJAP1 | ATXN7L2 | 0.650162 | 3 | 0 | 3 |
| TJAP1 | COL4A1 | 0.649822 | 9 | 0 | 8 |
| TJAP1 | MARCKSL1 | 0.649773 | 10 | 0 | 9 |
| TJAP1 | LENG1 | 0.647792 | 3 | 0 | 3 |
| TJAP1 | AGRN | 0.646852 | 10 | 0 | 9 |
For details and further investigation, click here
