| Full name: microfibril associated protein 2 | Alias Symbol: MAGP|MAGP-1 | ||
| Type: protein-coding gene | Cytoband: 1p36.13 | ||
| Entrez ID: 4237 | HGNC ID: HGNC:7033 | Ensembl Gene: ENSG00000117122 | OMIM ID: 156790 |
| Drug and gene relationship at DGIdb | |||
Expression of MFAP2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | MFAP2 | 4237 | 203417_at | 2.7453 | 0.0143 | |
| GSE20347 | MFAP2 | 4237 | 203417_at | 2.4107 | 0.0000 | |
| GSE23400 | MFAP2 | 4237 | 203417_at | 1.7967 | 0.0000 | |
| GSE26886 | MFAP2 | 4237 | 203417_at | 2.3909 | 0.0000 | |
| GSE29001 | MFAP2 | 4237 | 203417_at | 1.6372 | 0.0001 | |
| GSE38129 | MFAP2 | 4237 | 203417_at | 2.5140 | 0.0000 | |
| GSE45670 | MFAP2 | 4237 | 203417_at | 1.5403 | 0.0008 | |
| GSE53622 | MFAP2 | 4237 | 11775 | 3.6247 | 0.0000 | |
| GSE53624 | MFAP2 | 4237 | 11775 | 3.7100 | 0.0000 | |
| GSE63941 | MFAP2 | 4237 | 203417_at | -0.0382 | 0.9790 | |
| GSE77861 | MFAP2 | 4237 | 203417_at | 0.7935 | 0.0701 | |
| GSE97050 | MFAP2 | 4237 | A_23_P1029 | 2.1970 | 0.0706 | |
| SRP007169 | MFAP2 | 4237 | RNAseq | 6.0828 | 0.0000 | |
| SRP008496 | MFAP2 | 4237 | RNAseq | 5.9714 | 0.0000 | |
| SRP064894 | MFAP2 | 4237 | RNAseq | 3.8332 | 0.0000 | |
| SRP133303 | MFAP2 | 4237 | RNAseq | 3.9135 | 0.0000 | |
| SRP159526 | MFAP2 | 4237 | RNAseq | 3.8589 | 0.0000 | |
| SRP219564 | MFAP2 | 4237 | RNAseq | 3.2367 | 0.0000 | |
| TCGA | MFAP2 | 4237 | RNAseq | 1.2557 | 0.0000 |
Upregulated datasets: 16; Downregulated datasets: 0.
Survival by MFAP2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of MFAP2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | MFAP2 | 4237 | 0 | 5 | 25 | |
| GSE20123 | MFAP2 | 4237 | 0 | 4 | 26 | |
| GSE43470 | MFAP2 | 4237 | 1 | 8 | 34 | |
| GSE46452 | MFAP2 | 4237 | 5 | 1 | 53 | |
| GSE47630 | MFAP2 | 4237 | 8 | 3 | 29 | |
| GSE54993 | MFAP2 | 4237 | 3 | 1 | 66 | |
| GSE54994 | MFAP2 | 4237 | 10 | 4 | 39 | |
| GSE60625 | MFAP2 | 4237 | 0 | 0 | 11 | |
| GSE74703 | MFAP2 | 4237 | 1 | 5 | 30 | |
| GSE74704 | MFAP2 | 4237 | 0 | 0 | 20 | |
| TCGA | MFAP2 | 4237 | 9 | 23 | 64 |
Total number of gains: 37; Total number of losses: 54; Total Number of normals: 397.
Somatic mutations of MFAP2:
Generating mutation plots.
Highly correlated genes for MFAP2:
Showing top 20/2222 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| MFAP2 | LOXL2 | 0.85088 | 11 | 0 | 11 |
| MFAP2 | COL5A2 | 0.828803 | 12 | 0 | 12 |
| MFAP2 | INHBA | 0.826298 | 11 | 0 | 11 |
| MFAP2 | FNDC3B | 0.825694 | 11 | 0 | 11 |
| MFAP2 | CTHRC1 | 0.820795 | 9 | 0 | 8 |
| MFAP2 | SPP1 | 0.805659 | 11 | 0 | 11 |
| MFAP2 | VCAN | 0.803947 | 12 | 0 | 12 |
| MFAP2 | PLAU | 0.802292 | 12 | 0 | 11 |
| MFAP2 | LAMC2 | 0.80128 | 12 | 0 | 11 |
| MFAP2 | XPR1 | 0.800105 | 7 | 0 | 7 |
| MFAP2 | SERPINE1 | 0.799556 | 11 | 0 | 11 |
| MFAP2 | TTYH3 | 0.799074 | 8 | 0 | 8 |
| MFAP2 | FMNL2 | 0.798835 | 7 | 0 | 7 |
| MFAP2 | WDR66 | 0.79792 | 7 | 0 | 7 |
| MFAP2 | TGFBI | 0.794392 | 12 | 0 | 11 |
| MFAP2 | COL5A1 | 0.794258 | 13 | 0 | 12 |
| MFAP2 | GPX8 | 0.794202 | 7 | 0 | 7 |
| MFAP2 | COLGALT1 | 0.790659 | 10 | 0 | 10 |
| MFAP2 | SNX10 | 0.790361 | 11 | 0 | 11 |
| MFAP2 | MMP1 | 0.788352 | 12 | 0 | 11 |
For details and further investigation, click here
