| Full name: RFT1 homolog | Alias Symbol: CDG1N | ||
| Type: protein-coding gene | Cytoband: 3p21.1 | ||
| Entrez ID: 91869 | HGNC ID: HGNC:30220 | Ensembl Gene: ENSG00000163933 | OMIM ID: 611908 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of RFT1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | RFT1 | 91869 | 226060_at | 0.7419 | 0.0407 | |
| GSE26886 | RFT1 | 91869 | 226060_at | -0.1627 | 0.5130 | |
| GSE45670 | RFT1 | 91869 | 226060_at | 0.5040 | 0.0005 | |
| GSE53622 | RFT1 | 91869 | 4915 | 0.0713 | 0.4686 | |
| GSE53624 | RFT1 | 91869 | 4915 | 0.3844 | 0.0004 | |
| GSE63941 | RFT1 | 91869 | 226060_at | -0.0368 | 0.9287 | |
| GSE77861 | RFT1 | 91869 | 226060_at | -0.0531 | 0.6026 | |
| GSE97050 | RFT1 | 91869 | A_23_P155441 | 0.2000 | 0.4183 | |
| SRP007169 | RFT1 | 91869 | RNAseq | 0.1055 | 0.7893 | |
| SRP008496 | RFT1 | 91869 | RNAseq | -0.0558 | 0.8131 | |
| SRP064894 | RFT1 | 91869 | RNAseq | 0.4988 | 0.0004 | |
| SRP133303 | RFT1 | 91869 | RNAseq | 0.0188 | 0.8946 | |
| SRP159526 | RFT1 | 91869 | RNAseq | 0.3220 | 0.2579 | |
| SRP193095 | RFT1 | 91869 | RNAseq | -0.0263 | 0.7445 | |
| SRP219564 | RFT1 | 91869 | RNAseq | 0.2298 | 0.4667 | |
| TCGA | RFT1 | 91869 | RNAseq | -0.0916 | 0.1017 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by RFT1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of RFT1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | RFT1 | 91869 | 0 | 18 | 12 | |
| GSE20123 | RFT1 | 91869 | 0 | 19 | 11 | |
| GSE43470 | RFT1 | 91869 | 0 | 18 | 25 | |
| GSE46452 | RFT1 | 91869 | 2 | 17 | 40 | |
| GSE47630 | RFT1 | 91869 | 1 | 24 | 15 | |
| GSE54993 | RFT1 | 91869 | 6 | 2 | 62 | |
| GSE54994 | RFT1 | 91869 | 0 | 32 | 21 | |
| GSE60625 | RFT1 | 91869 | 5 | 0 | 6 | |
| GSE74703 | RFT1 | 91869 | 0 | 14 | 22 | |
| GSE74704 | RFT1 | 91869 | 0 | 12 | 8 | |
| TCGA | RFT1 | 91869 | 0 | 78 | 18 |
Total number of gains: 14; Total number of losses: 234; Total Number of normals: 240.
Somatic mutations of RFT1:
Generating mutation plots.
Highly correlated genes for RFT1:
Showing top 20/116 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| RFT1 | FEN1 | 0.801178 | 3 | 0 | 3 |
| RFT1 | CDC6 | 0.79621 | 3 | 0 | 3 |
| RFT1 | DNMT3B | 0.772991 | 3 | 0 | 3 |
| RFT1 | WDR53 | 0.756436 | 3 | 0 | 3 |
| RFT1 | ZBTB46 | 0.748779 | 3 | 0 | 3 |
| RFT1 | BUB1B | 0.741777 | 3 | 0 | 3 |
| RFT1 | CDCA5 | 0.741066 | 4 | 0 | 3 |
| RFT1 | POLE2 | 0.735982 | 3 | 0 | 3 |
| RFT1 | YEATS2 | 0.729561 | 3 | 0 | 3 |
| RFT1 | CDC20 | 0.728178 | 4 | 0 | 3 |
| RFT1 | LRR1 | 0.727627 | 4 | 0 | 4 |
| RFT1 | DHX9 | 0.716192 | 4 | 0 | 3 |
| RFT1 | KIF4A | 0.71429 | 4 | 0 | 3 |
| RFT1 | DCAF15 | 0.708271 | 3 | 0 | 3 |
| RFT1 | RAD51 | 0.70768 | 4 | 0 | 3 |
| RFT1 | KLHL14 | 0.704005 | 3 | 0 | 3 |
| RFT1 | PUS1 | 0.702836 | 4 | 0 | 3 |
| RFT1 | WDR74 | 0.702741 | 4 | 0 | 4 |
| RFT1 | RAD54B | 0.700603 | 4 | 0 | 3 |
| RFT1 | GALNS | 0.699427 | 3 | 0 | 3 |
For details and further investigation, click here
