| Full name: ALG3 alpha-1,3- mannosyltransferase | Alias Symbol: NOT56L|Not56|CDGS4|D16Ertd36e | ||
| Type: protein-coding gene | Cytoband: 3q27.1 | ||
| Entrez ID: 10195 | HGNC ID: HGNC:23056 | Ensembl Gene: ENSG00000214160 | OMIM ID: 608750 |
| Drug and gene relationship at DGIdb | |||
Expression of ALG3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ALG3 | 10195 | 207396_s_at | 0.6300 | 0.1059 | |
| GSE20347 | ALG3 | 10195 | 207396_s_at | 0.6379 | 0.0000 | |
| GSE23400 | ALG3 | 10195 | 207396_s_at | 0.6319 | 0.0000 | |
| GSE26886 | ALG3 | 10195 | 207396_s_at | 0.1271 | 0.5475 | |
| GSE29001 | ALG3 | 10195 | 207396_s_at | 0.7929 | 0.0148 | |
| GSE38129 | ALG3 | 10195 | 207396_s_at | 0.9313 | 0.0000 | |
| GSE45670 | ALG3 | 10195 | 207396_s_at | 0.5886 | 0.0011 | |
| GSE53622 | ALG3 | 10195 | 51314 | 0.7909 | 0.0000 | |
| GSE53624 | ALG3 | 10195 | 51314 | 1.2942 | 0.0000 | |
| GSE63941 | ALG3 | 10195 | 207396_s_at | 1.9421 | 0.0008 | |
| GSE77861 | ALG3 | 10195 | 207396_s_at | 0.3425 | 0.0942 | |
| GSE97050 | ALG3 | 10195 | A_24_P414269 | 0.4504 | 0.3601 | |
| SRP007169 | ALG3 | 10195 | RNAseq | 1.4421 | 0.0011 | |
| SRP008496 | ALG3 | 10195 | RNAseq | 1.2786 | 0.0000 | |
| SRP064894 | ALG3 | 10195 | RNAseq | 1.4605 | 0.0000 | |
| SRP133303 | ALG3 | 10195 | RNAseq | 1.1926 | 0.0000 | |
| SRP159526 | ALG3 | 10195 | RNAseq | 1.5752 | 0.0000 | |
| SRP193095 | ALG3 | 10195 | RNAseq | 1.0861 | 0.0000 | |
| SRP219564 | ALG3 | 10195 | RNAseq | 1.2162 | 0.0100 | |
| TCGA | ALG3 | 10195 | RNAseq | 0.4275 | 0.0000 |
Upregulated datasets: 9; Downregulated datasets: 0.
Survival by ALG3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ALG3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ALG3 | 10195 | 25 | 0 | 5 | |
| GSE20123 | ALG3 | 10195 | 25 | 0 | 5 | |
| GSE43470 | ALG3 | 10195 | 25 | 0 | 18 | |
| GSE46452 | ALG3 | 10195 | 19 | 1 | 39 | |
| GSE47630 | ALG3 | 10195 | 27 | 2 | 11 | |
| GSE54993 | ALG3 | 10195 | 1 | 19 | 50 | |
| GSE54994 | ALG3 | 10195 | 41 | 0 | 12 | |
| GSE60625 | ALG3 | 10195 | 0 | 6 | 5 | |
| GSE74703 | ALG3 | 10195 | 21 | 0 | 15 | |
| GSE74704 | ALG3 | 10195 | 17 | 0 | 3 | |
| TCGA | ALG3 | 10195 | 77 | 0 | 19 |
Total number of gains: 278; Total number of losses: 28; Total Number of normals: 182.
Somatic mutations of ALG3:
Generating mutation plots.
Highly correlated genes for ALG3:
Showing top 20/1910 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ALG3 | NACC1 | 0.80909 | 3 | 0 | 3 |
| ALG3 | MRPL47 | 0.80864 | 7 | 0 | 7 |
| ALG3 | MAP3K13 | 0.788976 | 7 | 0 | 7 |
| ALG3 | ABCF3 | 0.781055 | 13 | 0 | 12 |
| ALG3 | PSMG3 | 0.767358 | 6 | 0 | 6 |
| ALG3 | ACTL6A | 0.765424 | 11 | 0 | 10 |
| ALG3 | EBNA1BP2 | 0.753873 | 3 | 0 | 3 |
| ALG3 | ECE2 | 0.750747 | 9 | 0 | 8 |
| ALG3 | TBRG4 | 0.746746 | 4 | 0 | 4 |
| ALG3 | TBCCD1 | 0.746707 | 8 | 0 | 8 |
| ALG3 | UBE2C | 0.744694 | 11 | 0 | 11 |
| ALG3 | COMMD2 | 0.743862 | 5 | 0 | 5 |
| ALG3 | POLR2H | 0.740139 | 13 | 0 | 11 |
| ALG3 | PSMD2 | 0.73926 | 13 | 0 | 12 |
| ALG3 | LSM4 | 0.73584 | 10 | 0 | 10 |
| ALG3 | AP2M1 | 0.734655 | 13 | 0 | 12 |
| ALG3 | SEC61A1 | 0.734421 | 9 | 0 | 9 |
| ALG3 | EIF4G1 | 0.72974 | 11 | 0 | 11 |
| ALG3 | ALG1 | 0.729346 | 4 | 0 | 4 |
| ALG3 | DRAP1 | 0.724505 | 4 | 0 | 4 |
For details and further investigation, click here
