| Full name: tubulin alpha 1c | Alias Symbol: MGC14580|MGC10851|bcm948 | ||
| Type: protein-coding gene | Cytoband: 12q13.12 | ||
| Entrez ID: 84790 | HGNC ID: HGNC:20768 | Ensembl Gene: ENSG00000167553 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
TUBA1C involved pathways:
| KEGG pathway | Description | View |
|---|---|---|
| hsa04210 | Apoptosis | |
| hsa05130 | Pathogenic Escherichia coli infection |
Expression of TUBA1C:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TUBA1C | 84790 | 209251_x_at | 0.3028 | 0.1321 | |
| GSE20347 | TUBA1C | 84790 | 209251_x_at | 0.3738 | 0.0017 | |
| GSE23400 | TUBA1C | 84790 | 211750_x_at | 0.2629 | 0.0000 | |
| GSE26886 | TUBA1C | 84790 | 209251_x_at | -0.1167 | 0.4733 | |
| GSE29001 | TUBA1C | 84790 | 209251_x_at | 0.0236 | 0.9463 | |
| GSE38129 | TUBA1C | 84790 | 209251_x_at | 0.4834 | 0.0000 | |
| GSE45670 | TUBA1C | 84790 | 209251_x_at | 0.2585 | 0.0057 | |
| GSE63941 | TUBA1C | 84790 | 209251_x_at | 0.2379 | 0.4748 | |
| GSE77861 | TUBA1C | 84790 | 209251_x_at | 0.3645 | 0.0046 | |
| GSE97050 | TUBA1C | 84790 | A_24_P58529 | 1.0964 | 0.0594 | |
| SRP007169 | TUBA1C | 84790 | RNAseq | -0.9800 | 0.0023 | |
| SRP008496 | TUBA1C | 84790 | RNAseq | -0.8613 | 0.0000 | |
| SRP064894 | TUBA1C | 84790 | RNAseq | -0.0068 | 0.9798 | |
| SRP133303 | TUBA1C | 84790 | RNAseq | 0.1861 | 0.2235 | |
| SRP159526 | TUBA1C | 84790 | RNAseq | 0.0009 | 0.9979 | |
| SRP193095 | TUBA1C | 84790 | RNAseq | -0.0169 | 0.9345 | |
| SRP219564 | TUBA1C | 84790 | RNAseq | 0.0340 | 0.9573 | |
| TCGA | TUBA1C | 84790 | RNAseq | 0.3290 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by TUBA1C expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of TUBA1C:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TUBA1C | 84790 | 6 | 1 | 23 | |
| GSE20123 | TUBA1C | 84790 | 6 | 1 | 23 | |
| GSE43470 | TUBA1C | 84790 | 3 | 1 | 39 | |
| GSE46452 | TUBA1C | 84790 | 8 | 1 | 50 | |
| GSE47630 | TUBA1C | 84790 | 11 | 2 | 27 | |
| GSE54993 | TUBA1C | 84790 | 0 | 5 | 65 | |
| GSE54994 | TUBA1C | 84790 | 4 | 1 | 48 | |
| GSE60625 | TUBA1C | 84790 | 0 | 0 | 11 | |
| GSE74703 | TUBA1C | 84790 | 3 | 1 | 32 | |
| GSE74704 | TUBA1C | 84790 | 4 | 1 | 15 | |
| TCGA | TUBA1C | 84790 | 16 | 12 | 68 |
Total number of gains: 61; Total number of losses: 26; Total Number of normals: 401.
Somatic mutations of TUBA1C:
Generating mutation plots.
Highly correlated genes for TUBA1C:
Showing top 20/1126 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TUBA1C | TUBA1B | 0.877721 | 10 | 0 | 9 |
| TUBA1C | PSMG3 | 0.777111 | 3 | 0 | 3 |
| TUBA1C | AGAP2-AS1 | 0.772109 | 3 | 0 | 3 |
| TUBA1C | CD276 | 0.765872 | 4 | 0 | 4 |
| TUBA1C | XPR1 | 0.741695 | 3 | 0 | 3 |
| TUBA1C | TTL | 0.736613 | 3 | 0 | 3 |
| TUBA1C | PPP1R14C | 0.728271 | 3 | 0 | 3 |
| TUBA1C | UHRF1 | 0.728118 | 5 | 0 | 5 |
| TUBA1C | ANKRD52 | 0.726815 | 3 | 0 | 3 |
| TUBA1C | CDCA2 | 0.726072 | 4 | 0 | 4 |
| TUBA1C | TUBG1 | 0.722382 | 9 | 0 | 9 |
| TUBA1C | NR2C2AP | 0.72224 | 3 | 0 | 3 |
| TUBA1C | CDCA3 | 0.72174 | 7 | 0 | 7 |
| TUBA1C | SCYL1 | 0.717233 | 3 | 0 | 3 |
| TUBA1C | TUBB | 0.715911 | 11 | 0 | 10 |
| TUBA1C | USB1 | 0.711977 | 6 | 0 | 6 |
| TUBA1C | DNMT1 | 0.711954 | 7 | 0 | 7 |
| TUBA1C | CDC6 | 0.711575 | 7 | 0 | 7 |
| TUBA1C | TMEM184B | 0.709917 | 6 | 0 | 5 |
| TUBA1C | RHBDD2 | 0.709908 | 3 | 0 | 3 |
For details and further investigation, click here
