| Full name: listerin E3 ubiquitin protein ligase 1 | Alias Symbol: KIAA0714|FLJ11053|LISTERIN | ||
| Type: protein-coding gene | Cytoband: 21q21.3 | ||
| Entrez ID: 26046 | HGNC ID: HGNC:13082 | Ensembl Gene: ENSG00000198862 | OMIM ID: 613083 |
| Drug and gene relationship at DGIdb | |||
Expression of LTN1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | LTN1 | 26046 | 215596_s_at | -0.1544 | 0.7191 | |
| GSE20347 | LTN1 | 26046 | 215596_s_at | -0.2306 | 0.0830 | |
| GSE23400 | LTN1 | 26046 | 215596_s_at | 0.0832 | 0.3504 | |
| GSE26886 | LTN1 | 26046 | 215596_s_at | -0.5951 | 0.0005 | |
| GSE29001 | LTN1 | 26046 | 215596_s_at | 0.0924 | 0.7706 | |
| GSE38129 | LTN1 | 26046 | 215596_s_at | -0.2051 | 0.0475 | |
| GSE45670 | LTN1 | 26046 | 215596_s_at | -0.0838 | 0.6130 | |
| GSE53622 | LTN1 | 26046 | 40009 | -0.1752 | 0.0015 | |
| GSE53624 | LTN1 | 26046 | 40009 | 0.0047 | 0.9553 | |
| GSE63941 | LTN1 | 26046 | 215596_s_at | -0.5141 | 0.3722 | |
| GSE77861 | LTN1 | 26046 | 215596_s_at | -0.2581 | 0.3673 | |
| GSE97050 | LTN1 | 26046 | A_32_P115505 | -0.2253 | 0.3070 | |
| SRP007169 | LTN1 | 26046 | RNAseq | 0.0927 | 0.7635 | |
| SRP008496 | LTN1 | 26046 | RNAseq | 0.3845 | 0.0774 | |
| SRP064894 | LTN1 | 26046 | RNAseq | -0.1588 | 0.5803 | |
| SRP133303 | LTN1 | 26046 | RNAseq | -0.1021 | 0.3822 | |
| SRP159526 | LTN1 | 26046 | RNAseq | -0.6016 | 0.0408 | |
| SRP193095 | LTN1 | 26046 | RNAseq | -0.4197 | 0.0000 | |
| SRP219564 | LTN1 | 26046 | RNAseq | -0.6274 | 0.0802 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by LTN1 expression:
 |  |
| GSE53622 | GSE53624 |
Note: Click image to view full size file.
Copy number change of LTN1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | LTN1 | 26046 | 2 | 10 | 18 | |
| GSE20123 | LTN1 | 26046 | 2 | 10 | 18 | |
| GSE43470 | LTN1 | 26046 | 1 | 8 | 34 | |
| GSE46452 | LTN1 | 26046 | 1 | 21 | 37 | |
| GSE47630 | LTN1 | 26046 | 6 | 17 | 17 | |
| GSE54993 | LTN1 | 26046 | 9 | 1 | 60 | |
| GSE54994 | LTN1 | 26046 | 1 | 9 | 43 | |
| GSE60625 | LTN1 | 26046 | 0 | 0 | 11 | |
| GSE74703 | LTN1 | 26046 | 1 | 6 | 29 | |
| GSE74704 | LTN1 | 26046 | 2 | 6 | 12 | |
| TCGA | LTN1 | 26046 | 9 | 37 | 50 |
Total number of gains: 34; Total number of losses: 125; Total Number of normals: 329.
Somatic mutations of LTN1:
Generating mutation plots.
Highly correlated genes for LTN1:
Showing top 20/506 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| LTN1 | RHBDD1 | 0.81678 | 3 | 0 | 3 |
| LTN1 | CCNYL1 | 0.747783 | 3 | 0 | 3 |
| LTN1 | EAF1 | 0.745201 | 4 | 0 | 4 |
| LTN1 | NIPSNAP3A | 0.73593 | 4 | 0 | 4 |
| LTN1 | RPP30 | 0.727161 | 3 | 0 | 3 |
| LTN1 | PRPF38A | 0.725813 | 3 | 0 | 3 |
| LTN1 | ZRANB2 | 0.711751 | 3 | 0 | 3 |
| LTN1 | KIAA1143 | 0.708542 | 3 | 0 | 3 |
| LTN1 | CHM | 0.706628 | 3 | 0 | 3 |
| LTN1 | SLC37A3 | 0.706 | 3 | 0 | 3 |
| LTN1 | CRK | 0.705757 | 3 | 0 | 3 |
| LTN1 | ZNF649 | 0.70489 | 3 | 0 | 3 |
| LTN1 | AHCYL2 | 0.699329 | 3 | 0 | 3 |
| LTN1 | ABCG2 | 0.697888 | 3 | 0 | 3 |
| LTN1 | TMEM41B | 0.697609 | 3 | 0 | 3 |
| LTN1 | PTAR1 | 0.695741 | 3 | 0 | 3 |
| LTN1 | ARL6 | 0.694203 | 3 | 0 | 3 |
| LTN1 | FAM174A | 0.693288 | 3 | 0 | 3 |
| LTN1 | LARP1B | 0.691822 | 3 | 0 | 3 |
| LTN1 | SHPRH | 0.69128 | 3 | 0 | 3 |
For details and further investigation, click here
