| Full name: ubiquitin conjugating enzyme E2 N | Alias Symbol: UbcH-ben|UBC13|MGC8489 | ||
| Type: protein-coding gene | Cytoband: 12q22 | ||
| Entrez ID: 7334 | HGNC ID: HGNC:12492 | Ensembl Gene: ENSG00000177889 | OMIM ID: 603679 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
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Expression of UBE2N:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | UBE2N | 7334 | 201524_x_at | 0.0573 | 0.8665 | |
| GSE20347 | UBE2N | 7334 | 201524_x_at | -0.0125 | 0.9335 | |
| GSE23400 | UBE2N | 7334 | 201524_x_at | 0.0776 | 0.1088 | |
| GSE26886 | UBE2N | 7334 | 201524_x_at | 0.0309 | 0.8243 | |
| GSE29001 | UBE2N | 7334 | 201524_x_at | -0.1154 | 0.6378 | |
| GSE38129 | UBE2N | 7334 | 201524_x_at | 0.1377 | 0.2147 | |
| GSE45670 | UBE2N | 7334 | 201524_x_at | 0.1928 | 0.0569 | |
| GSE53622 | UBE2N | 7334 | 17900 | -0.1002 | 0.1997 | |
| GSE53624 | UBE2N | 7334 | 17900 | -0.1884 | 0.0598 | |
| GSE63941 | UBE2N | 7334 | 201524_x_at | 0.7359 | 0.0160 | |
| GSE77861 | UBE2N | 7334 | 201524_x_at | -0.0075 | 0.9720 | |
| GSE97050 | UBE2N | 7334 | A_23_P116829 | -0.5981 | 0.1894 | |
| SRP007169 | UBE2N | 7334 | RNAseq | -0.2508 | 0.4173 | |
| SRP008496 | UBE2N | 7334 | RNAseq | -0.1202 | 0.5299 | |
| SRP064894 | UBE2N | 7334 | RNAseq | -0.3159 | 0.0207 | |
| SRP133303 | UBE2N | 7334 | RNAseq | 0.1609 | 0.2779 | |
| SRP159526 | UBE2N | 7334 | RNAseq | -0.1390 | 0.5750 | |
| SRP193095 | UBE2N | 7334 | RNAseq | -0.2510 | 0.0159 | |
| SRP219564 | UBE2N | 7334 | RNAseq | -0.4326 | 0.0235 | |
| TCGA | UBE2N | 7334 | RNAseq | 0.0825 | 0.0702 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by UBE2N expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of UBE2N:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | UBE2N | 7334 | 3 | 2 | 25 | |
| GSE20123 | UBE2N | 7334 | 3 | 2 | 25 | |
| GSE43470 | UBE2N | 7334 | 3 | 0 | 40 | |
| GSE46452 | UBE2N | 7334 | 9 | 1 | 49 | |
| GSE47630 | UBE2N | 7334 | 10 | 1 | 29 | |
| GSE54993 | UBE2N | 7334 | 0 | 5 | 65 | |
| GSE54994 | UBE2N | 7334 | 6 | 1 | 46 | |
| GSE60625 | UBE2N | 7334 | 0 | 0 | 11 | |
| GSE74703 | UBE2N | 7334 | 3 | 0 | 33 | |
| GSE74704 | UBE2N | 7334 | 1 | 2 | 17 | |
| TCGA | UBE2N | 7334 | 17 | 11 | 68 |
Total number of gains: 55; Total number of losses: 25; Total Number of normals: 408.
Somatic mutations of UBE2N:
Generating mutation plots.
Highly correlated genes for UBE2N:
Showing top 20/394 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| UBE2N | COPS2 | 0.82622 | 3 | 0 | 3 |
| UBE2N | MTRF1L | 0.791044 | 3 | 0 | 3 |
| UBE2N | RPS19BP1 | 0.766665 | 3 | 0 | 3 |
| UBE2N | CUL1 | 0.748541 | 3 | 0 | 3 |
| UBE2N | TSHR | 0.740279 | 3 | 0 | 3 |
| UBE2N | PITHD1 | 0.738058 | 3 | 0 | 3 |
| UBE2N | TMEM218 | 0.730536 | 3 | 0 | 3 |
| UBE2N | IFT46 | 0.723354 | 3 | 0 | 3 |
| UBE2N | CTCF | 0.720282 | 4 | 0 | 4 |
| UBE2N | RAD18 | 0.718425 | 3 | 0 | 3 |
| UBE2N | COX5B | 0.718384 | 3 | 0 | 3 |
| UBE2N | ARL16 | 0.717829 | 4 | 0 | 3 |
| UBE2N | FRAT2 | 0.717081 | 3 | 0 | 3 |
| UBE2N | ZNF480 | 0.712779 | 3 | 0 | 3 |
| UBE2N | CHCHD5 | 0.710416 | 3 | 0 | 3 |
| UBE2N | TM9SF3 | 0.707531 | 4 | 0 | 4 |
| UBE2N | NFKB1 | 0.707124 | 4 | 0 | 3 |
| UBE2N | HSPA9 | 0.705225 | 3 | 0 | 3 |
| UBE2N | PSPC1 | 0.70518 | 3 | 0 | 3 |
| UBE2N | MORN2 | 0.702598 | 3 | 0 | 3 |
For details and further investigation, click here
