| Full name: dehydrogenase/reductase 12 | Alias Symbol: FLJ13639|SDR40C1 | ||
| Type: protein-coding gene | Cytoband: 13q14.3 | ||
| Entrez ID: 79758 | HGNC ID: HGNC:25832 | Ensembl Gene: ENSG00000102796 | OMIM ID: 616163 |
| Drug and gene relationship at DGIdb | |||
Expression of DHRS12:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | DHRS12 | 79758 | 204800_s_at | -0.5777 | 0.1601 | |
| GSE20347 | DHRS12 | 79758 | 204800_s_at | -0.7385 | 0.0000 | |
| GSE23400 | DHRS12 | 79758 | 204800_s_at | -0.3644 | 0.0000 | |
| GSE26886 | DHRS12 | 79758 | 204800_s_at | -0.2061 | 0.4034 | |
| GSE29001 | DHRS12 | 79758 | 204800_s_at | -0.7217 | 0.0002 | |
| GSE38129 | DHRS12 | 79758 | 204800_s_at | -0.7377 | 0.0000 | |
| GSE45670 | DHRS12 | 79758 | 204800_s_at | -0.7814 | 0.0001 | |
| GSE53622 | DHRS12 | 79758 | 83349 | -0.6525 | 0.0000 | |
| GSE53624 | DHRS12 | 79758 | 83349 | -0.6360 | 0.0000 | |
| GSE63941 | DHRS12 | 79758 | 204800_s_at | 0.1982 | 0.8089 | |
| GSE77861 | DHRS12 | 79758 | 204800_s_at | -0.4705 | 0.0059 | |
| GSE97050 | DHRS12 | 79758 | A_23_P205200 | -0.5582 | 0.1805 | |
| SRP007169 | DHRS12 | 79758 | RNAseq | -1.6773 | 0.0099 | |
| SRP064894 | DHRS12 | 79758 | RNAseq | -0.4966 | 0.0601 | |
| SRP133303 | DHRS12 | 79758 | RNAseq | -0.6442 | 0.0000 | |
| SRP159526 | DHRS12 | 79758 | RNAseq | -1.8010 | 0.0000 | |
| SRP193095 | DHRS12 | 79758 | RNAseq | -0.9100 | 0.0000 | |
| SRP219564 | DHRS12 | 79758 | RNAseq | -0.8195 | 0.0798 | |
| TCGA | DHRS12 | 79758 | RNAseq | -0.4270 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 2.
Survival by DHRS12 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of DHRS12:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | DHRS12 | 79758 | 1 | 12 | 17 | |
| GSE20123 | DHRS12 | 79758 | 1 | 11 | 18 | |
| GSE43470 | DHRS12 | 79758 | 3 | 12 | 28 | |
| GSE46452 | DHRS12 | 79758 | 0 | 32 | 27 | |
| GSE47630 | DHRS12 | 79758 | 2 | 27 | 11 | |
| GSE54993 | DHRS12 | 79758 | 12 | 2 | 56 | |
| GSE54994 | DHRS12 | 79758 | 1 | 15 | 37 | |
| GSE60625 | DHRS12 | 79758 | 0 | 3 | 8 | |
| GSE74703 | DHRS12 | 79758 | 3 | 10 | 23 | |
| GSE74704 | DHRS12 | 79758 | 0 | 8 | 12 | |
| TCGA | DHRS12 | 79758 | 9 | 36 | 51 |
Total number of gains: 32; Total number of losses: 168; Total Number of normals: 288.
Somatic mutations of DHRS12:
Generating mutation plots.
Highly correlated genes for DHRS12:
Showing top 20/1024 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| DHRS12 | SAT2 | 0.73547 | 3 | 0 | 3 |
| DHRS12 | TMEM220 | 0.733174 | 4 | 0 | 4 |
| DHRS12 | SOX8 | 0.712424 | 3 | 0 | 3 |
| DHRS12 | PDCD4 | 0.709713 | 4 | 0 | 4 |
| DHRS12 | KDM5D | 0.706153 | 3 | 0 | 3 |
| DHRS12 | SMR3B | 0.691685 | 3 | 0 | 3 |
| DHRS12 | ARHGAP10 | 0.691411 | 10 | 0 | 9 |
| DHRS12 | SLC25A27 | 0.687229 | 3 | 0 | 3 |
| DHRS12 | PARD3B | 0.686438 | 3 | 0 | 3 |
| DHRS12 | PADI1 | 0.6862 | 4 | 0 | 4 |
| DHRS12 | ABR | 0.682864 | 9 | 0 | 8 |
| DHRS12 | CREBRF | 0.681589 | 3 | 0 | 3 |
| DHRS12 | GBA2 | 0.67255 | 3 | 0 | 3 |
| DHRS12 | KIAA0232 | 0.669439 | 11 | 0 | 10 |
| DHRS12 | GADL1 | 0.66842 | 3 | 0 | 3 |
| DHRS12 | SLC24A3 | 0.668064 | 9 | 0 | 8 |
| DHRS12 | SORBS2 | 0.663489 | 9 | 0 | 9 |
| DHRS12 | FBXL3 | 0.660471 | 5 | 0 | 5 |
| DHRS12 | MTIF3 | 0.659989 | 7 | 0 | 7 |
| DHRS12 | PINK1 | 0.658488 | 7 | 0 | 6 |
For details and further investigation, click here
