| Full name: transmembrane protein 231 | Alias Symbol: FLJ22167|ALYE870|PRO1886|JBTS20|MKS11 | ||
| Type: protein-coding gene | Cytoband: 16q23.1 | ||
| Entrez ID: 79583 | HGNC ID: HGNC:37234 | Ensembl Gene: ENSG00000205084 | OMIM ID: 614949 |
| Drug and gene relationship at DGIdb | |||
Expression of TMEM231:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TMEM231 | 79583 | 64900_at | -0.2962 | 0.7869 | |
| GSE20347 | TMEM231 | 79583 | 64900_at | 0.1938 | 0.5212 | |
| GSE23400 | TMEM231 | 79583 | 64900_at | -0.0214 | 0.4772 | |
| GSE26886 | TMEM231 | 79583 | 64900_at | 0.5379 | 0.0513 | |
| GSE29001 | TMEM231 | 79583 | 64900_at | -0.3764 | 0.3030 | |
| GSE38129 | TMEM231 | 79583 | 64900_at | 0.2417 | 0.2939 | |
| GSE45670 | TMEM231 | 79583 | 64900_at | -0.3010 | 0.2920 | |
| GSE53622 | TMEM231 | 79583 | 17195 | -0.1632 | 0.2416 | |
| GSE53624 | TMEM231 | 79583 | 17195 | -0.1440 | 0.2407 | |
| GSE63941 | TMEM231 | 79583 | 64900_at | -1.6380 | 0.0316 | |
| GSE77861 | TMEM231 | 79583 | 64900_at | 0.3191 | 0.0610 | |
| GSE97050 | TMEM231 | 79583 | A_24_P381975 | 0.1420 | 0.5525 | |
| SRP007169 | TMEM231 | 79583 | RNAseq | -0.4108 | 0.4481 | |
| SRP008496 | TMEM231 | 79583 | RNAseq | -0.6101 | 0.0576 | |
| SRP064894 | TMEM231 | 79583 | RNAseq | -0.3521 | 0.0768 | |
| SRP133303 | TMEM231 | 79583 | RNAseq | 0.1204 | 0.6230 | |
| SRP159526 | TMEM231 | 79583 | RNAseq | 0.7871 | 0.0410 | |
| SRP193095 | TMEM231 | 79583 | RNAseq | -0.0702 | 0.7173 | |
| SRP219564 | TMEM231 | 79583 | RNAseq | 0.0385 | 0.9462 | |
| TCGA | TMEM231 | 79583 | RNAseq | -0.0394 | 0.8046 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by TMEM231 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TMEM231:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TMEM231 | 79583 | 5 | 0 | 25 | |
| GSE20123 | TMEM231 | 79583 | 5 | 0 | 25 | |
| GSE43470 | TMEM231 | 79583 | 2 | 7 | 34 | |
| GSE46452 | TMEM231 | 79583 | 37 | 2 | 20 | |
| GSE47630 | TMEM231 | 79583 | 11 | 8 | 21 | |
| GSE54993 | TMEM231 | 79583 | 2 | 4 | 64 | |
| GSE54994 | TMEM231 | 79583 | 8 | 10 | 35 | |
| GSE60625 | TMEM231 | 79583 | 4 | 0 | 7 | |
| GSE74703 | TMEM231 | 79583 | 2 | 5 | 29 | |
| GSE74704 | TMEM231 | 79583 | 2 | 0 | 18 | |
| TCGA | TMEM231 | 79583 | 24 | 15 | 57 |
Total number of gains: 102; Total number of losses: 51; Total Number of normals: 335.
Somatic mutations of TMEM231:
Generating mutation plots.
Highly correlated genes for TMEM231:
Showing top 20/137 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TMEM231 | ICK | 0.69593 | 3 | 0 | 3 |
| TMEM231 | P2RX4 | 0.68689 | 3 | 0 | 3 |
| TMEM231 | ZNF746 | 0.663021 | 3 | 0 | 3 |
| TMEM231 | CCDC88A | 0.64645 | 4 | 0 | 3 |
| TMEM231 | AP3M2 | 0.642488 | 4 | 0 | 3 |
| TMEM231 | TERF2IP | 0.632873 | 3 | 0 | 3 |
| TMEM231 | HTRA1 | 0.618129 | 4 | 0 | 3 |
| TMEM231 | MAGEA11 | 0.618015 | 3 | 0 | 3 |
| TMEM231 | CLPTM1L | 0.61716 | 3 | 0 | 3 |
| TMEM231 | HMGA2 | 0.617014 | 3 | 0 | 3 |
| TMEM231 | AGBL5 | 0.613044 | 5 | 0 | 3 |
| TMEM231 | LAYN | 0.611217 | 3 | 0 | 3 |
| TMEM231 | KRBOX4 | 0.610443 | 5 | 0 | 4 |
| TMEM231 | CLDN3 | 0.601522 | 5 | 0 | 4 |
| TMEM231 | ERLIN2 | 0.600415 | 4 | 0 | 3 |
| TMEM231 | RPARP-AS1 | 0.598566 | 4 | 0 | 4 |
| TMEM231 | PLOD1 | 0.594907 | 5 | 0 | 4 |
| TMEM231 | PEG10 | 0.589999 | 5 | 0 | 3 |
| TMEM231 | ORC5 | 0.587599 | 3 | 0 | 3 |
| TMEM231 | SERPINE2 | 0.586431 | 4 | 0 | 4 |
For details and further investigation, click here
