| Full name: ER lipid raft associated 2 | Alias Symbol: NET32|Erlin-2 | ||
| Type: protein-coding gene | Cytoband: 8p11.23 | ||
| Entrez ID: 11160 | HGNC ID: HGNC:1356 | Ensembl Gene: ENSG00000147475 | OMIM ID: 611605 |
| Drug and gene relationship at DGIdb | |||
Expression of ERLIN2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ERLIN2 | 11160 | 221543_s_at | 0.3472 | 0.6174 | |
| GSE20347 | ERLIN2 | 11160 | 221543_s_at | 0.3788 | 0.0350 | |
| GSE23400 | ERLIN2 | 11160 | 221543_s_at | 0.7315 | 0.0000 | |
| GSE26886 | ERLIN2 | 11160 | 221543_s_at | 0.0034 | 0.9937 | |
| GSE29001 | ERLIN2 | 11160 | 221543_s_at | 0.4864 | 0.2313 | |
| GSE38129 | ERLIN2 | 11160 | 221543_s_at | 0.4008 | 0.0097 | |
| GSE45670 | ERLIN2 | 11160 | 221543_s_at | 0.1166 | 0.6884 | |
| GSE53622 | ERLIN2 | 11160 | 79005 | 0.6414 | 0.0000 | |
| GSE53624 | ERLIN2 | 11160 | 101333 | 0.3021 | 0.0010 | |
| GSE63941 | ERLIN2 | 11160 | 221543_s_at | -1.1247 | 0.0094 | |
| GSE77861 | ERLIN2 | 11160 | 221543_s_at | 0.1110 | 0.8090 | |
| GSE97050 | ERLIN2 | 11160 | A_33_P3363061 | 0.3290 | 0.3142 | |
| SRP007169 | ERLIN2 | 11160 | RNAseq | 1.2491 | 0.0022 | |
| SRP008496 | ERLIN2 | 11160 | RNAseq | 1.4294 | 0.0000 | |
| SRP064894 | ERLIN2 | 11160 | RNAseq | 0.2525 | 0.2224 | |
| SRP133303 | ERLIN2 | 11160 | RNAseq | 0.4575 | 0.0378 | |
| SRP159526 | ERLIN2 | 11160 | RNAseq | 0.0449 | 0.8167 | |
| SRP193095 | ERLIN2 | 11160 | RNAseq | 0.3477 | 0.0222 | |
| SRP219564 | ERLIN2 | 11160 | RNAseq | 0.2208 | 0.5138 | |
| TCGA | ERLIN2 | 11160 | RNAseq | -0.0566 | 0.3457 |
Upregulated datasets: 2; Downregulated datasets: 1.
Survival by ERLIN2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ERLIN2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ERLIN2 | 11160 | 8 | 4 | 18 | |
| GSE20123 | ERLIN2 | 11160 | 9 | 4 | 17 | |
| GSE43470 | ERLIN2 | 11160 | 7 | 7 | 29 | |
| GSE46452 | ERLIN2 | 11160 | 20 | 7 | 32 | |
| GSE47630 | ERLIN2 | 11160 | 12 | 7 | 21 | |
| GSE54993 | ERLIN2 | 11160 | 2 | 16 | 52 | |
| GSE54994 | ERLIN2 | 11160 | 15 | 9 | 29 | |
| GSE60625 | ERLIN2 | 11160 | 3 | 0 | 8 | |
| GSE74703 | ERLIN2 | 11160 | 7 | 5 | 24 | |
| GSE74704 | ERLIN2 | 11160 | 7 | 1 | 12 | |
| TCGA | ERLIN2 | 11160 | 35 | 24 | 37 |
Total number of gains: 125; Total number of losses: 84; Total Number of normals: 279.
Somatic mutations of ERLIN2:
Generating mutation plots.
Highly correlated genes for ERLIN2:
Showing top 20/387 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ERLIN2 | MRPS35 | 0.7255 | 3 | 0 | 3 |
| ERLIN2 | LSM1 | 0.705144 | 11 | 0 | 11 |
| ERLIN2 | GRSF1 | 0.691726 | 3 | 0 | 3 |
| ERLIN2 | ANKRD16 | 0.689629 | 3 | 0 | 3 |
| ERLIN2 | ERP29 | 0.683297 | 3 | 0 | 3 |
| ERLIN2 | TTI2 | 0.68 | 7 | 0 | 6 |
| ERLIN2 | BAG4 | 0.679913 | 12 | 0 | 10 |
| ERLIN2 | FBXL3 | 0.678524 | 3 | 0 | 3 |
| ERLIN2 | CCDC93 | 0.673118 | 3 | 0 | 3 |
| ERLIN2 | KLHDC10 | 0.668483 | 3 | 0 | 3 |
| ERLIN2 | USP34 | 0.668319 | 4 | 0 | 3 |
| ERLIN2 | HPS3 | 0.668244 | 3 | 0 | 3 |
| ERLIN2 | RAD17 | 0.658806 | 4 | 0 | 3 |
| ERLIN2 | ASH2L | 0.654067 | 12 | 0 | 11 |
| ERLIN2 | GK5 | 0.651579 | 3 | 0 | 3 |
| ERLIN2 | GTF3C4 | 0.64805 | 5 | 0 | 4 |
| ERLIN2 | LEMD3 | 0.647365 | 5 | 0 | 3 |
| ERLIN2 | UBA5 | 0.645592 | 4 | 0 | 3 |
| ERLIN2 | SLC7A6 | 0.644879 | 4 | 0 | 3 |
| ERLIN2 | ERCC2 | 0.642144 | 3 | 0 | 3 |
For details and further investigation, click here
