| Full name: arylsulfatase family member I | Alias Symbol: FLJ16069|SPG66 | ||
| Type: protein-coding gene | Cytoband: 5q32 | ||
| Entrez ID: 340075 | HGNC ID: HGNC:32521 | Ensembl Gene: ENSG00000183876 | OMIM ID: 610009 |
| Drug and gene relationship at DGIdb | |||
Expression of ARSI:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ARSI | 340075 | 230275_at | 0.6085 | 0.4277 | |
| GSE26886 | ARSI | 340075 | 230275_at | 1.0560 | 0.0201 | |
| GSE45670 | ARSI | 340075 | 230275_at | 0.6405 | 0.0650 | |
| GSE53622 | ARSI | 340075 | 76646 | 1.0466 | 0.0000 | |
| GSE53624 | ARSI | 340075 | 76646 | 1.6682 | 0.0000 | |
| GSE63941 | ARSI | 340075 | 230275_at | -2.1187 | 0.0183 | |
| GSE77861 | ARSI | 340075 | 230275_at | -0.0599 | 0.7821 | |
| GSE97050 | ARSI | 340075 | A_23_P19030 | 0.3139 | 0.1857 | |
| SRP007169 | ARSI | 340075 | RNAseq | 3.1264 | 0.0034 | |
| SRP064894 | ARSI | 340075 | RNAseq | 2.4752 | 0.0000 | |
| SRP133303 | ARSI | 340075 | RNAseq | 3.0076 | 0.0000 | |
| SRP159526 | ARSI | 340075 | RNAseq | 1.8040 | 0.0025 | |
| SRP219564 | ARSI | 340075 | RNAseq | 1.0728 | 0.0867 | |
| TCGA | ARSI | 340075 | RNAseq | 1.1034 | 0.0000 |
Upregulated datasets: 8; Downregulated datasets: 1.
Survival by ARSI expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ARSI:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ARSI | 340075 | 1 | 12 | 17 | |
| GSE20123 | ARSI | 340075 | 1 | 12 | 17 | |
| GSE43470 | ARSI | 340075 | 1 | 10 | 32 | |
| GSE46452 | ARSI | 340075 | 0 | 27 | 32 | |
| GSE47630 | ARSI | 340075 | 0 | 20 | 20 | |
| GSE54993 | ARSI | 340075 | 9 | 1 | 60 | |
| GSE54994 | ARSI | 340075 | 2 | 15 | 36 | |
| GSE60625 | ARSI | 340075 | 0 | 0 | 11 | |
| GSE74703 | ARSI | 340075 | 1 | 7 | 28 | |
| GSE74704 | ARSI | 340075 | 1 | 7 | 12 | |
| TCGA | ARSI | 340075 | 5 | 37 | 54 |
Total number of gains: 21; Total number of losses: 148; Total Number of normals: 319.
Somatic mutations of ARSI:
Generating mutation plots.
Highly correlated genes for ARSI:
Showing top 20/740 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ARSI | NUTF2 | 0.742152 | 4 | 0 | 4 |
| ARSI | PDE8A | 0.738287 | 3 | 0 | 3 |
| ARSI | LOX | 0.728691 | 6 | 0 | 6 |
| ARSI | SPON2 | 0.725333 | 3 | 0 | 3 |
| ARSI | NXN | 0.723685 | 3 | 0 | 3 |
| ARSI | COL6A1 | 0.7213 | 5 | 0 | 5 |
| ARSI | COL5A3 | 0.71272 | 7 | 0 | 7 |
| ARSI | YKT6 | 0.708006 | 3 | 0 | 3 |
| ARSI | MRC2 | 0.707809 | 3 | 0 | 3 |
| ARSI | FLT4 | 0.707196 | 3 | 0 | 3 |
| ARSI | SLC2A9 | 0.704831 | 3 | 0 | 3 |
| ARSI | STC2 | 0.698625 | 5 | 0 | 5 |
| ARSI | THSD1 | 0.695472 | 3 | 0 | 3 |
| ARSI | AMIGO2 | 0.694176 | 5 | 0 | 5 |
| ARSI | LRRC8C | 0.691465 | 3 | 0 | 3 |
| ARSI | CXCL14 | 0.689168 | 4 | 0 | 4 |
| ARSI | CRISPLD2 | 0.68842 | 3 | 0 | 3 |
| ARSI | C11orf24 | 0.686852 | 7 | 0 | 6 |
| ARSI | PANX1 | 0.684729 | 7 | 0 | 5 |
| ARSI | FAM89A | 0.683033 | 3 | 0 | 3 |
For details and further investigation, click here
