| Full name: INO80 complex ATPase subunit | Alias Symbol: KIAA1259|Ino80|hINO80|INO80A | ||
| Type: protein-coding gene | Cytoband: 15q15.1 | ||
| Entrez ID: 54617 | HGNC ID: HGNC:26956 | Ensembl Gene: ENSG00000128908 | OMIM ID: 610169 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of INO80:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | INO80 | 54617 | 229356_x_at | -0.0361 | 0.8976 | |
| GSE26886 | INO80 | 54617 | 229356_x_at | 0.3667 | 0.0126 | |
| GSE45670 | INO80 | 54617 | 229356_x_at | -0.0098 | 0.9179 | |
| GSE53622 | INO80 | 54617 | 34823 | 0.0152 | 0.7818 | |
| GSE53624 | INO80 | 54617 | 50182 | -0.0132 | 0.8085 | |
| GSE63941 | INO80 | 54617 | 229356_x_at | 0.0472 | 0.8844 | |
| GSE77861 | INO80 | 54617 | 229356_x_at | -0.0165 | 0.9219 | |
| GSE97050 | INO80 | 54617 | A_33_P3291325 | -0.1718 | 0.4171 | |
| SRP007169 | INO80 | 54617 | RNAseq | 0.7336 | 0.0470 | |
| SRP008496 | INO80 | 54617 | RNAseq | 0.5686 | 0.0712 | |
| SRP064894 | INO80 | 54617 | RNAseq | -0.1336 | 0.4092 | |
| SRP133303 | INO80 | 54617 | RNAseq | 0.1027 | 0.4780 | |
| SRP159526 | INO80 | 54617 | RNAseq | -0.3183 | 0.2908 | |
| SRP193095 | INO80 | 54617 | RNAseq | 0.1250 | 0.1156 | |
| SRP219564 | INO80 | 54617 | RNAseq | 0.0238 | 0.9219 | |
| TCGA | INO80 | 54617 | RNAseq | -0.0314 | 0.5052 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by INO80 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of INO80:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | INO80 | 54617 | 3 | 6 | 21 | |
| GSE20123 | INO80 | 54617 | 3 | 6 | 21 | |
| GSE43470 | INO80 | 54617 | 4 | 6 | 33 | |
| GSE46452 | INO80 | 54617 | 3 | 7 | 49 | |
| GSE47630 | INO80 | 54617 | 8 | 11 | 21 | |
| GSE54993 | INO80 | 54617 | 4 | 6 | 60 | |
| GSE54994 | INO80 | 54617 | 6 | 7 | 40 | |
| GSE60625 | INO80 | 54617 | 4 | 0 | 7 | |
| GSE74703 | INO80 | 54617 | 4 | 5 | 27 | |
| GSE74704 | INO80 | 54617 | 2 | 4 | 14 | |
| TCGA | INO80 | 54617 | 11 | 18 | 67 |
Total number of gains: 52; Total number of losses: 76; Total Number of normals: 360.
Somatic mutations of INO80:
Generating mutation plots.
Highly correlated genes for INO80:
Showing top 20/97 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| INO80 | ANKRD54 | 0.731714 | 3 | 0 | 3 |
| INO80 | MAN1B1 | 0.724126 | 3 | 0 | 3 |
| INO80 | MCM3AP | 0.723884 | 3 | 0 | 3 |
| INO80 | UBE3A | 0.723678 | 4 | 0 | 4 |
| INO80 | TMEM41B | 0.721437 | 3 | 0 | 3 |
| INO80 | C12orf65 | 0.713693 | 3 | 0 | 3 |
| INO80 | VPS11 | 0.708604 | 3 | 0 | 3 |
| INO80 | SLC23A2 | 0.693668 | 3 | 0 | 3 |
| INO80 | EVI5L | 0.687715 | 3 | 0 | 3 |
| INO80 | CTDSP1 | 0.686176 | 3 | 0 | 3 |
| INO80 | PPP1R16A | 0.684395 | 3 | 0 | 3 |
| INO80 | SORBS3 | 0.678351 | 3 | 0 | 3 |
| INO80 | NPRL3 | 0.672795 | 3 | 0 | 3 |
| INO80 | TMEM150A | 0.667126 | 3 | 0 | 3 |
| INO80 | TADA3 | 0.665656 | 3 | 0 | 3 |
| INO80 | GHDC | 0.663636 | 3 | 0 | 3 |
| INO80 | CCDC59 | 0.661213 | 3 | 0 | 3 |
| INO80 | TMEM129 | 0.658491 | 4 | 0 | 4 |
| INO80 | CDK2AP2 | 0.655988 | 3 | 0 | 3 |
| INO80 | ARSD | 0.65535 | 3 | 0 | 3 |
For details and further investigation, click here
