| Full name: transmembrane protein 74B | Alias Symbol: FLJ11190 | ||
| Type: protein-coding gene | Cytoband: 20p13 | ||
| Entrez ID: 55321 | HGNC ID: HGNC:15893 | Ensembl Gene: ENSG00000125895 | OMIM ID: |
Expression of TMEM74B:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TMEM74B | 55321 | 219958_at | -0.0185 | 0.9646 | |
| GSE20347 | TMEM74B | 55321 | 219958_at | -0.0834 | 0.4690 | |
| GSE23400 | TMEM74B | 55321 | 219958_at | -0.0801 | 0.0485 | |
| GSE26886 | TMEM74B | 55321 | 219958_at | 0.3320 | 0.0373 | |
| GSE29001 | TMEM74B | 55321 | 219958_at | 0.0396 | 0.8424 | |
| GSE38129 | TMEM74B | 55321 | 219958_at | -0.1008 | 0.3920 | |
| GSE45670 | TMEM74B | 55321 | 219958_at | 0.1731 | 0.3377 | |
| GSE53622 | TMEM74B | 55321 | 24221 | 0.4806 | 0.0002 | |
| GSE53624 | TMEM74B | 55321 | 24221 | 0.2633 | 0.0069 | |
| GSE63941 | TMEM74B | 55321 | 219958_at | 0.8071 | 0.0487 | |
| GSE77861 | TMEM74B | 55321 | 219958_at | 0.0554 | 0.7878 | |
| SRP064894 | TMEM74B | 55321 | RNAseq | 1.1388 | 0.0002 | |
| SRP133303 | TMEM74B | 55321 | RNAseq | -0.2144 | 0.5211 | |
| SRP159526 | TMEM74B | 55321 | RNAseq | 0.8190 | 0.0535 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by TMEM74B expression:
 |  |
| GSE53622 | GSE53624 |
Note: Click image to view full size file.
Copy number change of TMEM74B:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TMEM74B | 55321 | 12 | 4 | 14 | |
| GSE20123 | TMEM74B | 55321 | 13 | 4 | 13 | |
| GSE43470 | TMEM74B | 55321 | 11 | 1 | 31 | |
| GSE46452 | TMEM74B | 55321 | 26 | 1 | 32 | |
| GSE47630 | TMEM74B | 55321 | 19 | 4 | 17 | |
| GSE54993 | TMEM74B | 55321 | 2 | 14 | 54 | |
| GSE54994 | TMEM74B | 55321 | 24 | 2 | 27 | |
| GSE60625 | TMEM74B | 55321 | 0 | 0 | 11 | |
| GSE74703 | TMEM74B | 55321 | 10 | 1 | 25 | |
| GSE74704 | TMEM74B | 55321 | 8 | 2 | 10 | |
| TCGA | TMEM74B | 55321 | 41 | 11 | 44 |
Total number of gains: 166; Total number of losses: 44; Total Number of normals: 278.
Somatic mutations of TMEM74B:
Generating mutation plots.
Highly correlated genes for TMEM74B:
Showing top 20/132 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TMEM74B | PRB4 | 0.640097 | 4 | 0 | 4 |
| TMEM74B | SHBG | 0.628955 | 3 | 0 | 3 |
| TMEM74B | LPA | 0.628933 | 3 | 0 | 3 |
| TMEM74B | PTPRO | 0.623715 | 3 | 0 | 3 |
| TMEM74B | HHLA1 | 0.617621 | 3 | 0 | 3 |
| TMEM74B | KHDRBS2 | 0.615484 | 4 | 0 | 4 |
| TMEM74B | RAD52 | 0.611671 | 4 | 0 | 4 |
| TMEM74B | ST8SIA2 | 0.606286 | 5 | 0 | 5 |
| TMEM74B | CITED1 | 0.60325 | 4 | 0 | 3 |
| TMEM74B | ASGR1 | 0.598978 | 5 | 0 | 4 |
| TMEM74B | SHOX | 0.597507 | 3 | 0 | 3 |
| TMEM74B | NEUROD4 | 0.596444 | 4 | 0 | 3 |
| TMEM74B | GFRA4 | 0.592868 | 3 | 0 | 3 |
| TMEM74B | MUC3B | 0.592402 | 5 | 0 | 3 |
| TMEM74B | KIF1A | 0.592182 | 4 | 0 | 3 |
| TMEM74B | KCNC1 | 0.588676 | 3 | 0 | 3 |
| TMEM74B | PLA2G2E | 0.585679 | 4 | 0 | 3 |
| TMEM74B | CLUH | 0.583298 | 3 | 0 | 3 |
| TMEM74B | TMPRSS5 | 0.582984 | 3 | 0 | 3 |
| TMEM74B | GRPR | 0.581196 | 4 | 0 | 4 |
For details and further investigation, click here
