| Full name: asialoglycoprotein receptor 1 | Alias Symbol: CLEC4H1 | ||
| Type: protein-coding gene | Cytoband: 17p13.1 | ||
| Entrez ID: 432 | HGNC ID: HGNC:742 | Ensembl Gene: ENSG00000141505 | OMIM ID: 108360 |
| Drug and gene relationship at DGIdb | |||
Expression of ASGR1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ASGR1 | 432 | 206743_s_at | -0.0883 | 0.7854 | |
| GSE20347 | ASGR1 | 432 | 206743_s_at | -0.1706 | 0.0127 | |
| GSE23400 | ASGR1 | 432 | 206743_s_at | -0.1509 | 0.0000 | |
| GSE26886 | ASGR1 | 432 | 206743_s_at | -0.2717 | 0.0462 | |
| GSE29001 | ASGR1 | 432 | 206743_s_at | -0.1767 | 0.2426 | |
| GSE38129 | ASGR1 | 432 | 206743_s_at | -0.1564 | 0.0432 | |
| GSE45670 | ASGR1 | 432 | 206743_s_at | -0.1343 | 0.4060 | |
| GSE53622 | ASGR1 | 432 | 78628 | -0.1669 | 0.0916 | |
| GSE53624 | ASGR1 | 432 | 78628 | -0.1551 | 0.0883 | |
| GSE63941 | ASGR1 | 432 | 206743_s_at | -0.0198 | 0.9441 | |
| GSE77861 | ASGR1 | 432 | 206743_s_at | 0.0817 | 0.4471 | |
| SRP159526 | ASGR1 | 432 | RNAseq | 0.4225 | 0.5017 | |
| SRP219564 | ASGR1 | 432 | RNAseq | 0.0084 | 0.9879 | |
| TCGA | ASGR1 | 432 | RNAseq | 0.3813 | 0.2089 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by ASGR1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ASGR1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ASGR1 | 432 | 4 | 2 | 24 | |
| GSE20123 | ASGR1 | 432 | 4 | 3 | 23 | |
| GSE43470 | ASGR1 | 432 | 1 | 4 | 38 | |
| GSE46452 | ASGR1 | 432 | 34 | 1 | 24 | |
| GSE47630 | ASGR1 | 432 | 7 | 1 | 32 | |
| GSE54993 | ASGR1 | 432 | 4 | 3 | 63 | |
| GSE54994 | ASGR1 | 432 | 5 | 8 | 40 | |
| GSE60625 | ASGR1 | 432 | 4 | 0 | 7 | |
| GSE74703 | ASGR1 | 432 | 1 | 2 | 33 | |
| GSE74704 | ASGR1 | 432 | 2 | 1 | 17 | |
| TCGA | ASGR1 | 432 | 17 | 21 | 58 |
Total number of gains: 83; Total number of losses: 46; Total Number of normals: 359.
Somatic mutations of ASGR1:
Generating mutation plots.
Highly correlated genes for ASGR1:
Showing top 20/117 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ASGR1 | KRTAP5-8 | 0.690678 | 3 | 0 | 3 |
| ASGR1 | SLC10A1 | 0.676592 | 3 | 0 | 3 |
| ASGR1 | KCNJ6 | 0.634267 | 3 | 0 | 3 |
| ASGR1 | PRAMEF10 | 0.634205 | 5 | 0 | 5 |
| ASGR1 | CCL24 | 0.632117 | 4 | 0 | 3 |
| ASGR1 | NCR2 | 0.629668 | 3 | 0 | 3 |
| ASGR1 | CACFD1 | 0.62822 | 3 | 0 | 3 |
| ASGR1 | HAAO | 0.619821 | 4 | 0 | 3 |
| ASGR1 | GBX1 | 0.616337 | 3 | 0 | 3 |
| ASGR1 | INO80D | 0.616013 | 3 | 0 | 3 |
| ASGR1 | FBP2 | 0.613306 | 4 | 0 | 4 |
| ASGR1 | MYO1A | 0.612874 | 3 | 0 | 3 |
| ASGR1 | TSSK2 | 0.607761 | 5 | 0 | 4 |
| ASGR1 | RAMP3 | 0.600891 | 4 | 0 | 3 |
| ASGR1 | MORN1 | 0.600377 | 3 | 0 | 3 |
| ASGR1 | ADH6 | 0.59919 | 3 | 0 | 3 |
| ASGR1 | TMEM74B | 0.598978 | 5 | 0 | 4 |
| ASGR1 | RAX | 0.598619 | 4 | 0 | 4 |
| ASGR1 | TTC39A | 0.593128 | 4 | 0 | 3 |
| ASGR1 | GPR15 | 0.590604 | 4 | 0 | 3 |
For details and further investigation, click here
