| Full name: kinesin family member 1A | Alias Symbol: UNC104 | ||
| Type: protein-coding gene | Cytoband: 2q37.3 | ||
| Entrez ID: 547 | HGNC ID: HGNC:888 | Ensembl Gene: ENSG00000130294 | OMIM ID: 601255 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of KIF1A:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | KIF1A | 547 | 225482_at | 0.0020 | 0.9973 | |
| GSE20347 | KIF1A | 547 | 203849_s_at | -0.0381 | 0.6629 | |
| GSE23400 | KIF1A | 547 | 203849_s_at | -0.0713 | 0.0099 | |
| GSE26886 | KIF1A | 547 | 225482_at | 0.0880 | 0.3910 | |
| GSE29001 | KIF1A | 547 | 203849_s_at | 0.5984 | 0.1819 | |
| GSE38129 | KIF1A | 547 | 203849_s_at | -0.0439 | 0.8236 | |
| GSE45670 | KIF1A | 547 | 225482_at | 0.0281 | 0.8239 | |
| GSE53622 | KIF1A | 547 | 16298 | 0.8329 | 0.0082 | |
| GSE53624 | KIF1A | 547 | 16298 | 0.9335 | 0.0001 | |
| GSE63941 | KIF1A | 547 | 225482_at | 0.3115 | 0.5430 | |
| GSE77861 | KIF1A | 547 | 225482_at | 0.3528 | 0.4753 | |
| TCGA | KIF1A | 547 | RNAseq | -1.0641 | 0.1047 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by KIF1A expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of KIF1A:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | KIF1A | 547 | 1 | 12 | 17 | |
| GSE20123 | KIF1A | 547 | 1 | 12 | 17 | |
| GSE43470 | KIF1A | 547 | 1 | 9 | 33 | |
| GSE46452 | KIF1A | 547 | 0 | 5 | 54 | |
| GSE47630 | KIF1A | 547 | 4 | 5 | 31 | |
| GSE54993 | KIF1A | 547 | 4 | 3 | 63 | |
| GSE54994 | KIF1A | 547 | 8 | 9 | 36 | |
| GSE60625 | KIF1A | 547 | 0 | 3 | 8 | |
| GSE74703 | KIF1A | 547 | 1 | 7 | 28 | |
| GSE74704 | KIF1A | 547 | 1 | 5 | 14 | |
| TCGA | KIF1A | 547 | 11 | 29 | 56 |
Total number of gains: 32; Total number of losses: 99; Total Number of normals: 357.
Somatic mutations of KIF1A:
Generating mutation plots.
Highly correlated genes for KIF1A:
Showing top 20/127 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| KIF1A | GABRB1 | 0.714097 | 5 | 0 | 5 |
| KIF1A | LINC01260 | 0.66637 | 3 | 0 | 3 |
| KIF1A | SCGN | 0.662712 | 4 | 0 | 3 |
| KIF1A | TTLL7 | 0.628762 | 3 | 0 | 3 |
| KIF1A | NOTUM | 0.626463 | 4 | 0 | 3 |
| KIF1A | SPSB4 | 0.621819 | 3 | 0 | 3 |
| KIF1A | TMPRSS3 | 0.621189 | 4 | 0 | 3 |
| KIF1A | DLK1 | 0.618819 | 5 | 0 | 3 |
| KIF1A | ATP2B2 | 0.615923 | 4 | 0 | 3 |
| KIF1A | SHH | 0.609777 | 5 | 0 | 3 |
| KIF1A | ZMAT4 | 0.608905 | 5 | 0 | 4 |
| KIF1A | NOS1 | 0.608634 | 3 | 0 | 3 |
| KIF1A | TAGLN3 | 0.60836 | 4 | 0 | 3 |
| KIF1A | KIR2DS3 | 0.606315 | 3 | 0 | 3 |
| KIF1A | PRODH2 | 0.60374 | 4 | 0 | 4 |
| KIF1A | RBP3 | 0.601157 | 3 | 0 | 3 |
| KIF1A | CXCR4 | 0.599781 | 4 | 0 | 3 |
| KIF1A | SAG | 0.597829 | 3 | 0 | 3 |
| KIF1A | GRIP2 | 0.594866 | 3 | 0 | 3 |
| KIF1A | GPC4 | 0.594546 | 5 | 0 | 3 |
For details and further investigation, click here
