| Full name: clustered mitochondria homolog | Alias Symbol: CLU1 | ||
| Type: protein-coding gene | Cytoband: 17p13.3 | ||
| Entrez ID: 23277 | HGNC ID: HGNC:29094 | Ensembl Gene: ENSG00000132361 | OMIM ID: 616184 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of CLUH:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CLUH | 23277 | 212456_at | 0.4704 | 0.3685 | |
| GSE20347 | CLUH | 23277 | 212456_at | 0.0870 | 0.4940 | |
| GSE23400 | CLUH | 23277 | 212456_at | -0.0080 | 0.9128 | |
| GSE26886 | CLUH | 23277 | 212456_at | 0.5500 | 0.0018 | |
| GSE29001 | CLUH | 23277 | 212456_at | -0.0582 | 0.8941 | |
| GSE38129 | CLUH | 23277 | 212456_at | 0.1013 | 0.4623 | |
| GSE45670 | CLUH | 23277 | 212456_at | 0.1697 | 0.2444 | |
| GSE53622 | CLUH | 23277 | 62877 | -0.2056 | 0.0252 | |
| GSE53624 | CLUH | 23277 | 62877 | 0.1478 | 0.0448 | |
| GSE63941 | CLUH | 23277 | 212456_at | 1.0532 | 0.0018 | |
| GSE77861 | CLUH | 23277 | 212456_at | 0.0067 | 0.9763 | |
| SRP007169 | CLUH | 23277 | RNAseq | 0.4268 | 0.2025 | |
| SRP008496 | CLUH | 23277 | RNAseq | 0.0916 | 0.7884 | |
| SRP064894 | CLUH | 23277 | RNAseq | -0.1224 | 0.5559 | |
| SRP133303 | CLUH | 23277 | RNAseq | -0.4305 | 0.0127 | |
| SRP159526 | CLUH | 23277 | RNAseq | -0.0899 | 0.7155 | |
| SRP193095 | CLUH | 23277 | RNAseq | 0.0490 | 0.6956 | |
| SRP219564 | CLUH | 23277 | RNAseq | 0.3117 | 0.5986 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by CLUH expression:
 |  |
| GSE53622 | GSE53624 |
Note: Click image to view full size file.
Copy number change of CLUH:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CLUH | 23277 | 4 | 2 | 24 | |
| GSE20123 | CLUH | 23277 | 4 | 3 | 23 | |
| GSE43470 | CLUH | 23277 | 1 | 6 | 36 | |
| GSE46452 | CLUH | 23277 | 34 | 1 | 24 | |
| GSE47630 | CLUH | 23277 | 7 | 1 | 32 | |
| GSE54993 | CLUH | 23277 | 4 | 3 | 63 | |
| GSE54994 | CLUH | 23277 | 5 | 9 | 39 | |
| GSE60625 | CLUH | 23277 | 4 | 0 | 7 | |
| GSE74703 | CLUH | 23277 | 1 | 3 | 32 | |
| GSE74704 | CLUH | 23277 | 2 | 1 | 17 | |
| TCGA | CLUH | 23277 | 16 | 21 | 59 |
Total number of gains: 82; Total number of losses: 50; Total Number of normals: 356.
Somatic mutations of CLUH:
Generating mutation plots.
Highly correlated genes for CLUH:
Showing top 20/300 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CLUH | SNRPE | 0.717315 | 3 | 0 | 3 |
| CLUH | TTF1 | 0.714276 | 3 | 0 | 3 |
| CLUH | WDR5 | 0.687808 | 3 | 0 | 3 |
| CLUH | SURF6 | 0.684016 | 4 | 0 | 3 |
| CLUH | BUB3 | 0.677652 | 3 | 0 | 3 |
| CLUH | ZMIZ2 | 0.661439 | 3 | 0 | 3 |
| CLUH | DHX36 | 0.657427 | 3 | 0 | 3 |
| CLUH | WDR75 | 0.657009 | 3 | 0 | 3 |
| CLUH | CMSS1 | 0.656428 | 3 | 0 | 3 |
| CLUH | UBQLN4 | 0.652744 | 5 | 0 | 5 |
| CLUH | NOP58 | 0.64874 | 4 | 0 | 3 |
| CLUH | PUSL1 | 0.644437 | 3 | 0 | 3 |
| CLUH | DDX19A | 0.642692 | 3 | 0 | 3 |
| CLUH | GTPBP8 | 0.635999 | 3 | 0 | 3 |
| CLUH | NUP43 | 0.635461 | 3 | 0 | 3 |
| CLUH | ZNF593 | 0.634093 | 3 | 0 | 3 |
| CLUH | EEF1E1 | 0.632815 | 3 | 0 | 3 |
| CLUH | NASP | 0.631822 | 3 | 0 | 3 |
| CLUH | POLR1B | 0.623249 | 6 | 0 | 5 |
| CLUH | MRPS17 | 0.621261 | 4 | 0 | 3 |
For details and further investigation, click here
