| Full name: ring finger protein 39 | Alias Symbol: HZFw1|LIRF | ||
| Type: protein-coding gene | Cytoband: 6p22.1 | ||
| Entrez ID: 80352 | HGNC ID: HGNC:18064 | Ensembl Gene: ENSG00000204618 | OMIM ID: 607524 |
| Drug and gene relationship at DGIdb | |||
Expression of RNF39:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | RNF39 | 80352 | 219916_s_at | -1.0354 | 0.2056 | |
| GSE20347 | RNF39 | 80352 | 219916_s_at | -1.2711 | 0.0000 | |
| GSE23400 | RNF39 | 80352 | 219916_s_at | -0.7162 | 0.0000 | |
| GSE26886 | RNF39 | 80352 | 219916_s_at | -2.7670 | 0.0000 | |
| GSE29001 | RNF39 | 80352 | 219916_s_at | -1.0531 | 0.0024 | |
| GSE38129 | RNF39 | 80352 | 219916_s_at | -0.9253 | 0.0002 | |
| GSE45670 | RNF39 | 80352 | 219916_s_at | -0.2944 | 0.2960 | |
| GSE53622 | RNF39 | 80352 | 69669 | -1.3618 | 0.0000 | |
| GSE53624 | RNF39 | 80352 | 69669 | -1.8430 | 0.0000 | |
| GSE63941 | RNF39 | 80352 | 219916_s_at | 0.4801 | 0.1886 | |
| GSE77861 | RNF39 | 80352 | 219916_s_at | -1.1286 | 0.0035 | |
| GSE97050 | RNF39 | 80352 | A_24_P314931 | -0.1808 | 0.7472 | |
| SRP007169 | RNF39 | 80352 | RNAseq | -4.3320 | 0.0000 | |
| SRP064894 | RNF39 | 80352 | RNAseq | -2.8649 | 0.0000 | |
| SRP133303 | RNF39 | 80352 | RNAseq | -2.3389 | 0.0000 | |
| SRP159526 | RNF39 | 80352 | RNAseq | -2.1101 | 0.0001 | |
| SRP193095 | RNF39 | 80352 | RNAseq | -1.8164 | 0.0000 | |
| SRP219564 | RNF39 | 80352 | RNAseq | -2.3583 | 0.0293 | |
| TCGA | RNF39 | 80352 | RNAseq | 0.1619 | 0.4183 |
Upregulated datasets: 0; Downregulated datasets: 12.
Survival by RNF39 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of RNF39:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | RNF39 | 80352 | 4 | 1 | 25 | |
| GSE20123 | RNF39 | 80352 | 4 | 1 | 25 | |
| GSE43470 | RNF39 | 80352 | 5 | 0 | 38 | |
| GSE46452 | RNF39 | 80352 | 1 | 10 | 48 | |
| GSE47630 | RNF39 | 80352 | 7 | 3 | 30 | |
| GSE54993 | RNF39 | 80352 | 2 | 1 | 67 | |
| GSE54994 | RNF39 | 80352 | 11 | 4 | 38 | |
| GSE60625 | RNF39 | 80352 | 0 | 1 | 10 | |
| GSE74703 | RNF39 | 80352 | 5 | 0 | 31 | |
| GSE74704 | RNF39 | 80352 | 2 | 0 | 18 | |
| TCGA | RNF39 | 80352 | 16 | 17 | 63 |
Total number of gains: 57; Total number of losses: 38; Total Number of normals: 393.
Somatic mutations of RNF39:
Generating mutation plots.
Highly correlated genes for RNF39:
Showing top 20/1136 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| RNF39 | TTC22 | 0.772779 | 11 | 0 | 11 |
| RNF39 | EVPL | 0.76313 | 12 | 0 | 11 |
| RNF39 | CYP2C18 | 0.760331 | 9 | 0 | 9 |
| RNF39 | RAET1E | 0.756908 | 8 | 0 | 7 |
| RNF39 | IL36A | 0.755309 | 10 | 0 | 10 |
| RNF39 | PRSS2 | 0.753081 | 9 | 0 | 8 |
| RNF39 | SULT2B1 | 0.75134 | 10 | 0 | 10 |
| RNF39 | SPRR2A | 0.750357 | 4 | 0 | 4 |
| RNF39 | RAB27B | 0.747505 | 9 | 0 | 9 |
| RNF39 | CRCT1 | 0.746695 | 12 | 0 | 11 |
| RNF39 | EPS8L1 | 0.746518 | 13 | 0 | 12 |
| RNF39 | TEKT5 | 0.745437 | 3 | 0 | 3 |
| RNF39 | PIM1 | 0.742516 | 11 | 0 | 10 |
| RNF39 | SPRR2F | 0.741955 | 4 | 0 | 4 |
| RNF39 | SH3GL1 | 0.740465 | 10 | 0 | 10 |
| RNF39 | TMEM154 | 0.73832 | 7 | 0 | 6 |
| RNF39 | GDPD3 | 0.737808 | 12 | 0 | 10 |
| RNF39 | TRIP10 | 0.735734 | 11 | 0 | 10 |
| RNF39 | DUOX1 | 0.73308 | 12 | 0 | 11 |
| RNF39 | MXD1 | 0.732334 | 12 | 0 | 11 |
For details and further investigation, click here
