TMEM87B

 

Full name: transmembrane protein 87B Alias Symbol: FLJ14681
Type: protein-coding gene Cytoband: 2q13
Entrez ID: 84910 HGNC ID: HGNC:25913 Ensembl Gene: ENSG00000153214 OMIM ID: 617203
Drug and gene relationship at DGIdb

 

Expression of TMEM87B:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 TMEM87B 84910 225411_at 0.4169 0.5186
GSE26886 TMEM87B 84910 225411_at -0.4693 0.1103
GSE45670 TMEM87B 84910 225411_at 0.0325 0.8962
GSE53622 TMEM87B 84910 27396 0.3822 0.0000
GSE53624 TMEM87B 84910 27396 0.2201 0.0003
GSE63941 TMEM87B 84910 225411_at -1.4655 0.0057
GSE77861 TMEM87B 84910 225412_at 0.9208 0.0013
GSE97050 TMEM87B 84910 A_23_P91076 0.5108 0.1479
SRP007169 TMEM87B 84910 RNAseq 0.6876 0.0445
SRP008496 TMEM87B 84910 RNAseq 1.1138 0.0000
SRP064894 TMEM87B 84910 RNAseq 0.5263 0.0205
SRP133303 TMEM87B 84910 RNAseq 0.7414 0.0000
SRP159526 TMEM87B 84910 RNAseq -0.0216 0.9427
SRP193095 TMEM87B 84910 RNAseq -0.0894 0.5227
SRP219564 TMEM87B 84910 RNAseq 0.0638 0.8537
TCGA TMEM87B 84910 RNAseq 0.0047 0.9258

Upregulated datasets: 1; Downregulated datasets: 1.  


 

Survival by TMEM87B expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  


Copy number change of TMEM87B:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 TMEM87B 84910 6 2 22
GSE20123 TMEM87B 84910 6 2 22
GSE43470 TMEM87B 84910 3 1 39
GSE46452 TMEM87B 84910 1 4 54
GSE47630 TMEM87B 84910 7 0 33
GSE54993 TMEM87B 84910 0 6 64
GSE54994 TMEM87B 84910 10 0 43
GSE60625 TMEM87B 84910 0 3 8
GSE74703 TMEM87B 84910 3 1 32
GSE74704 TMEM87B 84910 3 2 15
TCGA TMEM87B 84910 31 5 60

Total number of gains: 70; Total number of losses: 26; Total Number of normals: 392.  


 

Somatic mutations of TMEM87B:

 

Generating mutation plots.

 

Highly correlated genes for TMEM87B:

 

Showing top 20/159 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
TMEM87BTMEM1810.746485303
TMEM87BLRIF10.710784303
TMEM87BGGNBP20.704615303
TMEM87BBOD1L10.692776303
TMEM87BTAF1A0.687973404
TMEM87BCCDC930.687894303
TMEM87BUFM10.685147303
TMEM87BPAK20.682861303
TMEM87BNAA250.675573303
TMEM87BZSCAN290.674144303
TMEM87BSETX0.667535303
TMEM87BPSPC10.666492303
TMEM87BORAI20.664075403
TMEM87BC2orf490.664026303
TMEM87BPHTF20.658618303
TMEM87BTPST10.653952303
TMEM87BLIMK20.64814303
TMEM87BGTPBP40.645983303
TMEM87BMEST0.645467403
TMEM87BDNAJC100.645173503

For details and further investigation, click here