TAF1A

 

Full name: TATA-box binding protein associated factor, RNA polymerase I subunit A Alias Symbol: TAFI48|SL1
Type: protein-coding gene Cytoband: 1q41
Entrez ID: 9015 HGNC ID: HGNC:11532 Ensembl Gene: ENSG00000143498 OMIM ID: 604903
Drug and gene relationship at DGIdb
Screen Evidence:

 

Expression of TAF1A:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 TAF1A 9015 206613_s_at 1.6917 0.0155
GSE20347 TAF1A 9015 206613_s_at 1.0174 0.0000
GSE23400 TAF1A 9015 206613_s_at 0.5010 0.0000
GSE26886 TAF1A 9015 206613_s_at 0.1021 0.7948
GSE29001 TAF1A 9015 206613_s_at 1.4917 0.0001
GSE38129 TAF1A 9015 206613_s_at 1.3266 0.0000
GSE45670 TAF1A 9015 206613_s_at 1.1425 0.0001
GSE53622 TAF1A 9015 55629 1.1569 0.0000
GSE53624 TAF1A 9015 33103 1.2491 0.0000
GSE63941 TAF1A 9015 206613_s_at 0.8442 0.1117
GSE77861 TAF1A 9015 206613_s_at 0.4635 0.0270
GSE97050 TAF1A 9015 A_33_P3406245 0.6720 0.1883
SRP007169 TAF1A 9015 RNAseq 1.2795 0.0249
SRP008496 TAF1A 9015 RNAseq 0.8225 0.0431
SRP064894 TAF1A 9015 RNAseq 1.0322 0.0001
SRP133303 TAF1A 9015 RNAseq 0.9440 0.0000
SRP159526 TAF1A 9015 RNAseq 0.8601 0.0575
SRP193095 TAF1A 9015 RNAseq 0.3354 0.0060
SRP219564 TAF1A 9015 RNAseq 0.9219 0.0115
TCGA TAF1A 9015 RNAseq 0.4320 0.0000

Upregulated datasets: 9; Downregulated datasets: 0.  

 

Survival by TAF1A expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of TAF1A:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 TAF1A 9015 10 0 20
GSE20123 TAF1A 9015 10 0 20
GSE43470 TAF1A 9015 7 0 36
GSE46452 TAF1A 9015 3 1 55
GSE47630 TAF1A 9015 15 0 25
GSE54993 TAF1A 9015 0 6 64
GSE54994 TAF1A 9015 16 0 37
GSE60625 TAF1A 9015 0 0 11
GSE74703 TAF1A 9015 7 0 29
GSE74704 TAF1A 9015 4 0 16
TCGA TAF1A 9015 45 3 48

Total number of gains: 117; Total number of losses: 10; Total Number of normals: 361.  

 

Somatic mutations of TAF1A:

 

Generating mutation plots.

 

Highly correlated genes for TAF1A:

 

Showing top 20/1652 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
TAF1ACENPL0.784712505
TAF1ACBX30.7814410010
TAF1ACDCA50.7792505
TAF1AECT20.7777911010
TAF1ALAMC20.76485410010
TAF1ACDC60.762877707
TAF1ADESI20.7556051009
TAF1AFZD60.75284707
TAF1ARAD51AP10.74913112010
TAF1AFANCI0.74770110010
TAF1ASNAI20.747441707
TAF1ACENPF0.74656211010
TAF1ACKS1B0.74607613011
TAF1AFEN10.743916808
TAF1AMEST0.74321310010
TAF1ATMEM1380.741296606
TAF1AKIF140.73899812010
TAF1ACDK10.73895911010
TAF1AFOXM10.73604111010
TAF1ABID0.73528911010

For details and further investigation, click here