| Full name: tyrosylprotein sulfotransferase 1 | Alias Symbol: TANGO13A | ||
| Type: protein-coding gene | Cytoband: 7q11.21 | ||
| Entrez ID: 8460 | HGNC ID: HGNC:12020 | Ensembl Gene: ENSG00000169902 | OMIM ID: 603125 |
| Drug and gene relationship at DGIdb | |||
Expression of TPST1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TPST1 | 8460 | 204140_at | 0.2254 | 0.7277 | |
| GSE20347 | TPST1 | 8460 | 204140_at | 0.9023 | 0.0002 | |
| GSE23400 | TPST1 | 8460 | 204140_at | 0.3060 | 0.0000 | |
| GSE26886 | TPST1 | 8460 | 204140_at | 0.8139 | 0.0348 | |
| GSE29001 | TPST1 | 8460 | 204140_at | 0.4091 | 0.1707 | |
| GSE38129 | TPST1 | 8460 | 204140_at | 0.8956 | 0.0000 | |
| GSE45670 | TPST1 | 8460 | 204140_at | 0.0231 | 0.9400 | |
| GSE53622 | TPST1 | 8460 | 38963 | 0.7115 | 0.0000 | |
| GSE53624 | TPST1 | 8460 | 38963 | 0.7824 | 0.0000 | |
| GSE63941 | TPST1 | 8460 | 204140_at | -3.1200 | 0.0002 | |
| GSE77861 | TPST1 | 8460 | 204140_at | 0.4492 | 0.0887 | |
| GSE97050 | TPST1 | 8460 | A_23_P145965 | 0.4749 | 0.2433 | |
| SRP007169 | TPST1 | 8460 | RNAseq | 0.0424 | 0.8966 | |
| SRP008496 | TPST1 | 8460 | RNAseq | 0.5801 | 0.0241 | |
| SRP064894 | TPST1 | 8460 | RNAseq | 0.6229 | 0.0016 | |
| SRP133303 | TPST1 | 8460 | RNAseq | 0.5896 | 0.0067 | |
| SRP159526 | TPST1 | 8460 | RNAseq | 0.7644 | 0.0052 | |
| SRP193095 | TPST1 | 8460 | RNAseq | 0.8907 | 0.0001 | |
| SRP219564 | TPST1 | 8460 | RNAseq | 0.4677 | 0.3148 | |
| TCGA | TPST1 | 8460 | RNAseq | 0.1903 | 0.0417 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by TPST1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TPST1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TPST1 | 8460 | 11 | 2 | 17 | |
| GSE20123 | TPST1 | 8460 | 10 | 2 | 18 | |
| GSE43470 | TPST1 | 8460 | 2 | 1 | 40 | |
| GSE46452 | TPST1 | 8460 | 13 | 0 | 46 | |
| GSE47630 | TPST1 | 8460 | 7 | 1 | 32 | |
| GSE54993 | TPST1 | 8460 | 2 | 7 | 61 | |
| GSE54994 | TPST1 | 8460 | 12 | 4 | 37 | |
| GSE60625 | TPST1 | 8460 | 0 | 0 | 11 | |
| GSE74703 | TPST1 | 8460 | 2 | 1 | 33 | |
| GSE74704 | TPST1 | 8460 | 5 | 1 | 14 | |
| TCGA | TPST1 | 8460 | 46 | 6 | 44 |
Total number of gains: 110; Total number of losses: 25; Total Number of normals: 353.
Somatic mutations of TPST1:
Generating mutation plots.
Highly correlated genes for TPST1:
Showing top 20/348 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TPST1 | TNFSF13B | 0.71982 | 3 | 0 | 3 |
| TPST1 | POU5F2 | 0.658148 | 3 | 0 | 3 |
| TPST1 | TMEM87B | 0.653952 | 3 | 0 | 3 |
| TPST1 | RCN2 | 0.636527 | 7 | 0 | 5 |
| TPST1 | SURF4 | 0.635076 | 4 | 0 | 3 |
| TPST1 | ERP29 | 0.633075 | 3 | 0 | 3 |
| TPST1 | BCL2A1 | 0.618069 | 6 | 0 | 6 |
| TPST1 | POFUT2 | 0.613438 | 5 | 0 | 4 |
| TPST1 | BEND6 | 0.61254 | 4 | 0 | 4 |
| TPST1 | SHISA2 | 0.609524 | 4 | 0 | 4 |
| TPST1 | TMEM263 | 0.60898 | 6 | 0 | 5 |
| TPST1 | STRADA | 0.606601 | 3 | 0 | 3 |
| TPST1 | MFAP2 | 0.601285 | 10 | 0 | 9 |
| TPST1 | DSEL | 0.600973 | 5 | 0 | 4 |
| TPST1 | SLC25A24 | 0.600119 | 4 | 0 | 3 |
| TPST1 | B3GNT9 | 0.598577 | 5 | 0 | 4 |
| TPST1 | MB21D2 | 0.596138 | 5 | 0 | 5 |
| TPST1 | GPR68 | 0.594304 | 4 | 0 | 3 |
| TPST1 | ADAMTS12 | 0.594046 | 7 | 0 | 6 |
| TPST1 | KLF11 | 0.593127 | 4 | 0 | 4 |
For details and further investigation, click here
