| Full name: transmembrane inner ear | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 3p21.31 | ||
| Entrez ID: 259236 | HGNC ID: HGNC:30800 | Ensembl Gene: ENSG00000181585 | OMIM ID: 607237 |
| Drug and gene relationship at DGIdb | |||
Expression of TMIE:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TMIE | 259236 | 1553600_at | -0.0953 | 0.7096 | |
| GSE26886 | TMIE | 259236 | 1553600_at | 0.0919 | 0.5863 | |
| GSE45670 | TMIE | 259236 | 1553600_at | -0.0159 | 0.9038 | |
| GSE63941 | TMIE | 259236 | 1553600_at | 0.3137 | 0.0883 | |
| GSE77861 | TMIE | 259236 | 1553600_at | -0.2793 | 0.1412 | |
| SRP064894 | TMIE | 259236 | RNAseq | -1.4247 | 0.0028 | |
| SRP133303 | TMIE | 259236 | RNAseq | -1.6756 | 0.0000 | |
| SRP159526 | TMIE | 259236 | RNAseq | -2.6039 | 0.0000 | |
| SRP219564 | TMIE | 259236 | RNAseq | -1.7031 | 0.0062 | |
| TCGA | TMIE | 259236 | RNAseq | -0.4799 | 0.2493 |
Upregulated datasets: 0; Downregulated datasets: 4.
Survival by TMIE expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of TMIE:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TMIE | 259236 | 0 | 18 | 12 | |
| GSE20123 | TMIE | 259236 | 0 | 19 | 11 | |
| GSE43470 | TMIE | 259236 | 0 | 19 | 24 | |
| GSE46452 | TMIE | 259236 | 2 | 17 | 40 | |
| GSE47630 | TMIE | 259236 | 2 | 23 | 15 | |
| GSE54993 | TMIE | 259236 | 7 | 2 | 61 | |
| GSE54994 | TMIE | 259236 | 0 | 36 | 17 | |
| GSE60625 | TMIE | 259236 | 5 | 0 | 6 | |
| GSE74703 | TMIE | 259236 | 0 | 15 | 21 | |
| GSE74704 | TMIE | 259236 | 0 | 12 | 8 | |
| TCGA | TMIE | 259236 | 1 | 75 | 20 |
Total number of gains: 17; Total number of losses: 236; Total Number of normals: 235.
Somatic mutations of TMIE:
Generating mutation plots.
Highly correlated genes for TMIE:
Showing top 20/68 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TMIE | AP4S1 | 0.68479 | 3 | 0 | 3 |
| TMIE | APOA4 | 0.661249 | 4 | 0 | 4 |
| TMIE | PATE1 | 0.661162 | 4 | 0 | 3 |
| TMIE | DNAH9 | 0.658413 | 3 | 0 | 3 |
| TMIE | PNMA3 | 0.648606 | 3 | 0 | 3 |
| TMIE | CCR10 | 0.647206 | 3 | 0 | 3 |
| TMIE | HHLA3 | 0.635609 | 3 | 0 | 3 |
| TMIE | FUZ | 0.631311 | 3 | 0 | 3 |
| TMIE | TXNDC2 | 0.626619 | 3 | 0 | 3 |
| TMIE | ZMYND10 | 0.623005 | 3 | 0 | 3 |
| TMIE | BIRC7 | 0.618577 | 4 | 0 | 4 |
| TMIE | GATA5 | 0.609415 | 4 | 0 | 3 |
| TMIE | P2RX2 | 0.608858 | 3 | 0 | 3 |
| TMIE | ENHO | 0.60508 | 3 | 0 | 3 |
| TMIE | GABRD | 0.60448 | 3 | 0 | 3 |
| TMIE | TF | 0.599009 | 3 | 0 | 3 |
| TMIE | ROM1 | 0.596381 | 3 | 0 | 3 |
| TMIE | GNG8 | 0.595556 | 4 | 0 | 3 |
| TMIE | OPRD1 | 0.594273 | 3 | 0 | 3 |
| TMIE | REG3A | 0.584816 | 3 | 0 | 3 |
For details and further investigation, click here
