| Full name: GATA binding protein 5 | Alias Symbol: bB379O24.1|GATAS | ||
| Type: protein-coding gene | Cytoband: 20q13.33 | ||
| Entrez ID: 140628 | HGNC ID: HGNC:15802 | Ensembl Gene: ENSG00000130700 | OMIM ID: 611496 |
| Drug and gene relationship at DGIdb | |||
Expression of GATA5:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | GATA5 | 140628 | 238197_at | -0.1275 | 0.4970 | |
| GSE26886 | GATA5 | 140628 | 238095_at | 0.1766 | 0.0908 | |
| GSE45670 | GATA5 | 140628 | 238095_at | 0.0487 | 0.5857 | |
| GSE53622 | GATA5 | 140628 | 46151 | -0.3827 | 0.1493 | |
| GSE53624 | GATA5 | 140628 | 46151 | -0.5802 | 0.0119 | |
| GSE63941 | GATA5 | 140628 | 238095_at | 0.1083 | 0.6030 | |
| GSE77861 | GATA5 | 140628 | 238095_at | -0.0572 | 0.5475 | |
| TCGA | GATA5 | 140628 | RNAseq | -4.3690 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by GATA5 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of GATA5:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | GATA5 | 140628 | 14 | 2 | 14 | |
| GSE20123 | GATA5 | 140628 | 14 | 2 | 14 | |
| GSE43470 | GATA5 | 140628 | 11 | 1 | 31 | |
| GSE46452 | GATA5 | 140628 | 35 | 0 | 24 | |
| GSE47630 | GATA5 | 140628 | 25 | 1 | 14 | |
| GSE54993 | GATA5 | 140628 | 0 | 17 | 53 | |
| GSE54994 | GATA5 | 140628 | 29 | 0 | 24 | |
| GSE60625 | GATA5 | 140628 | 0 | 0 | 11 | |
| GSE74703 | GATA5 | 140628 | 10 | 0 | 26 | |
| GSE74704 | GATA5 | 140628 | 11 | 0 | 9 | |
| TCGA | GATA5 | 140628 | 43 | 4 | 49 |
Total number of gains: 192; Total number of losses: 27; Total Number of normals: 269.
Somatic mutations of GATA5:
Generating mutation plots.
Highly correlated genes for GATA5:
Showing top 20/49 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| GATA5 | PFDN1 | 0.710569 | 3 | 0 | 3 |
| GATA5 | C2CD4B | 0.649357 | 4 | 0 | 3 |
| GATA5 | TM4SF5 | 0.648452 | 3 | 0 | 3 |
| GATA5 | NPR1 | 0.643429 | 3 | 0 | 3 |
| GATA5 | NPTXR | 0.621113 | 4 | 0 | 3 |
| GATA5 | WNT7A | 0.620983 | 3 | 0 | 3 |
| GATA5 | EFCAB13 | 0.618155 | 4 | 0 | 4 |
| GATA5 | FAM171A2 | 0.611707 | 3 | 0 | 3 |
| GATA5 | TMIE | 0.609415 | 4 | 0 | 3 |
| GATA5 | AVPR2 | 0.604053 | 4 | 0 | 4 |
| GATA5 | ZMYND10 | 0.601812 | 3 | 0 | 3 |
| GATA5 | CST11 | 0.595657 | 3 | 0 | 3 |
| GATA5 | PGC | 0.595517 | 4 | 0 | 3 |
| GATA5 | SSPO | 0.586121 | 4 | 0 | 3 |
| GATA5 | GATA4 | 0.585804 | 4 | 0 | 4 |
| GATA5 | REEP2 | 0.585338 | 3 | 0 | 3 |
| GATA5 | GPR162 | 0.584621 | 3 | 0 | 3 |
| GATA5 | KRT35 | 0.582211 | 3 | 0 | 3 |
| GATA5 | KRT20 | 0.58057 | 3 | 0 | 3 |
| GATA5 | HBM | 0.576547 | 3 | 0 | 3 |
For details and further investigation, click here
