| Full name: transmembrane serine protease 11D | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 4q13.2 | ||
| Entrez ID: 9407 | HGNC ID: HGNC:24059 | Ensembl Gene: ENSG00000153802 | OMIM ID: 605369 |
| Drug and gene relationship at DGIdb | |||
Expression of TMPRSS11D:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TMPRSS11D | 9407 | 207602_at | -1.7712 | 0.4729 | |
| GSE20347 | TMPRSS11D | 9407 | 207602_at | -2.5577 | 0.0000 | |
| GSE23400 | TMPRSS11D | 9407 | 207602_at | -2.4135 | 0.0000 | |
| GSE26886 | TMPRSS11D | 9407 | 207602_at | -5.2826 | 0.0000 | |
| GSE29001 | TMPRSS11D | 9407 | 207602_at | -2.4006 | 0.0009 | |
| GSE38129 | TMPRSS11D | 9407 | 207602_at | -1.7763 | 0.0039 | |
| GSE45670 | TMPRSS11D | 9407 | 207602_at | -0.0827 | 0.8888 | |
| GSE53622 | TMPRSS11D | 9407 | 13851 | -1.6348 | 0.0000 | |
| GSE53624 | TMPRSS11D | 9407 | 13851 | -2.3316 | 0.0000 | |
| GSE63941 | TMPRSS11D | 9407 | 207602_at | -0.1162 | 0.8720 | |
| GSE77861 | TMPRSS11D | 9407 | 207602_at | -1.6177 | 0.0509 | |
| GSE97050 | TMPRSS11D | 9407 | A_33_P3374678 | 0.4071 | 0.5241 | |
| SRP007169 | TMPRSS11D | 9407 | RNAseq | -3.5685 | 0.0000 | |
| SRP008496 | TMPRSS11D | 9407 | RNAseq | -4.1431 | 0.0000 | |
| SRP064894 | TMPRSS11D | 9407 | RNAseq | -2.2410 | 0.0003 | |
| SRP133303 | TMPRSS11D | 9407 | RNAseq | -1.4833 | 0.0007 | |
| SRP159526 | TMPRSS11D | 9407 | RNAseq | -2.2146 | 0.0233 | |
| SRP219564 | TMPRSS11D | 9407 | RNAseq | -3.0850 | 0.0327 | |
| TCGA | TMPRSS11D | 9407 | RNAseq | 1.1927 | 0.0017 |
Upregulated datasets: 1; Downregulated datasets: 13.
Survival by TMPRSS11D expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TMPRSS11D:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TMPRSS11D | 9407 | 2 | 11 | 17 | |
| GSE20123 | TMPRSS11D | 9407 | 2 | 12 | 16 | |
| GSE43470 | TMPRSS11D | 9407 | 0 | 13 | 30 | |
| GSE46452 | TMPRSS11D | 9407 | 2 | 35 | 22 | |
| GSE47630 | TMPRSS11D | 9407 | 0 | 19 | 21 | |
| GSE54993 | TMPRSS11D | 9407 | 7 | 0 | 63 | |
| GSE54994 | TMPRSS11D | 9407 | 1 | 9 | 43 | |
| GSE60625 | TMPRSS11D | 9407 | 0 | 0 | 11 | |
| GSE74703 | TMPRSS11D | 9407 | 0 | 11 | 25 | |
| GSE74704 | TMPRSS11D | 9407 | 1 | 8 | 11 | |
| TCGA | TMPRSS11D | 9407 | 18 | 26 | 52 |
Total number of gains: 33; Total number of losses: 144; Total Number of normals: 311.
Somatic mutations of TMPRSS11D:
Generating mutation plots.
Highly correlated genes for TMPRSS11D:
Showing top 20/1386 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TMPRSS11D | TMPRSS11E | 0.852653 | 11 | 0 | 11 |
| TMPRSS11D | TGM1 | 0.847848 | 12 | 0 | 12 |
| TMPRSS11D | PGLYRP3 | 0.815517 | 4 | 0 | 4 |
| TMPRSS11D | PPL | 0.807019 | 12 | 0 | 12 |
| TMPRSS11D | IL1RN | 0.806616 | 12 | 0 | 11 |
| TMPRSS11D | SCEL | 0.804441 | 12 | 0 | 12 |
| TMPRSS11D | CYSRT1 | 0.7972 | 6 | 0 | 6 |
| TMPRSS11D | TMEM40 | 0.789641 | 12 | 0 | 11 |
| TMPRSS11D | CLIC3 | 0.787928 | 10 | 0 | 10 |
| TMPRSS11D | TMEM45B | 0.786424 | 8 | 0 | 7 |
| TMPRSS11D | KLK11 | 0.783175 | 12 | 0 | 12 |
| TMPRSS11D | ZNF185 | 0.782522 | 12 | 0 | 12 |
| TMPRSS11D | SPRR2A | 0.780642 | 4 | 0 | 4 |
| TMPRSS11D | ATP10B | 0.779106 | 10 | 0 | 10 |
| TMPRSS11D | RHCG | 0.778756 | 13 | 0 | 12 |
| TMPRSS11D | SPRR1A | 0.777926 | 13 | 0 | 13 |
| TMPRSS11D | MALL | 0.777764 | 12 | 0 | 12 |
| TMPRSS11D | CLCA4 | 0.776834 | 12 | 0 | 12 |
| TMPRSS11D | IL36RN | 0.775052 | 8 | 0 | 8 |
| TMPRSS11D | GLTP | 0.774571 | 10 | 0 | 10 |
For details and further investigation, click here
