| Full name: TNF alpha induced protein 8 like 3 | Alias Symbol: FLJ41287 | ||
| Type: protein-coding gene | Cytoband: 15q21.2 | ||
| Entrez ID: 388121 | HGNC ID: HGNC:20620 | Ensembl Gene: ENSG00000183578 | OMIM ID: 616438 |
| Drug and gene relationship at DGIdb | |||
Expression of TNFAIP8L3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TNFAIP8L3 | 388121 | 234279_at | -0.2138 | 0.3141 | |
| GSE26886 | TNFAIP8L3 | 388121 | 234279_at | 0.2298 | 0.1362 | |
| GSE45670 | TNFAIP8L3 | 388121 | 234279_at | -0.5157 | 0.0057 | |
| GSE53622 | TNFAIP8L3 | 388121 | 94556 | -1.3824 | 0.0000 | |
| GSE53624 | TNFAIP8L3 | 388121 | 94556 | -1.7934 | 0.0000 | |
| GSE63941 | TNFAIP8L3 | 388121 | 234279_at | -0.9115 | 0.0000 | |
| GSE77861 | TNFAIP8L3 | 388121 | 234279_at | -0.2356 | 0.2124 | |
| GSE97050 | TNFAIP8L3 | 388121 | A_32_P59010 | -0.2489 | 0.2470 | |
| SRP007169 | TNFAIP8L3 | 388121 | RNAseq | -3.8015 | 0.0000 | |
| SRP008496 | TNFAIP8L3 | 388121 | RNAseq | -3.5817 | 0.0000 | |
| SRP064894 | TNFAIP8L3 | 388121 | RNAseq | -1.5621 | 0.0000 | |
| SRP133303 | TNFAIP8L3 | 388121 | RNAseq | -1.1634 | 0.0000 | |
| SRP159526 | TNFAIP8L3 | 388121 | RNAseq | -1.8700 | 0.0000 | |
| SRP193095 | TNFAIP8L3 | 388121 | RNAseq | -0.7950 | 0.0011 | |
| SRP219564 | TNFAIP8L3 | 388121 | RNAseq | -0.9341 | 0.1665 | |
| TCGA | TNFAIP8L3 | 388121 | RNAseq | -0.3952 | 0.0125 |
Upregulated datasets: 0; Downregulated datasets: 7.
Survival by TNFAIP8L3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TNFAIP8L3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TNFAIP8L3 | 388121 | 5 | 3 | 22 | |
| GSE20123 | TNFAIP8L3 | 388121 | 5 | 3 | 22 | |
| GSE43470 | TNFAIP8L3 | 388121 | 5 | 3 | 35 | |
| GSE46452 | TNFAIP8L3 | 388121 | 3 | 7 | 49 | |
| GSE47630 | TNFAIP8L3 | 388121 | 8 | 10 | 22 | |
| GSE54993 | TNFAIP8L3 | 388121 | 4 | 6 | 60 | |
| GSE54994 | TNFAIP8L3 | 388121 | 5 | 7 | 41 | |
| GSE60625 | TNFAIP8L3 | 388121 | 4 | 0 | 7 | |
| GSE74703 | TNFAIP8L3 | 388121 | 5 | 2 | 29 | |
| GSE74704 | TNFAIP8L3 | 388121 | 2 | 3 | 15 | |
| TCGA | TNFAIP8L3 | 388121 | 9 | 17 | 70 |
Total number of gains: 55; Total number of losses: 61; Total Number of normals: 372.
Somatic mutations of TNFAIP8L3:
Generating mutation plots.
Highly correlated genes for TNFAIP8L3:
Showing top 20/614 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TNFAIP8L3 | SLIT3 | 0.738707 | 4 | 0 | 4 |
| TNFAIP8L3 | PCDH18 | 0.726336 | 3 | 0 | 3 |
| TNFAIP8L3 | AFF3 | 0.723473 | 3 | 0 | 3 |
| TNFAIP8L3 | BMP4 | 0.695603 | 3 | 0 | 3 |
| TNFAIP8L3 | RBFOX3 | 0.694156 | 3 | 0 | 3 |
| TNFAIP8L3 | FHOD3 | 0.69232 | 3 | 0 | 3 |
| TNFAIP8L3 | GNA14 | 0.687977 | 7 | 0 | 6 |
| TNFAIP8L3 | PALLD | 0.686167 | 3 | 0 | 3 |
| TNFAIP8L3 | RERGL | 0.685837 | 5 | 0 | 4 |
| TNFAIP8L3 | C7orf57 | 0.685136 | 3 | 0 | 3 |
| TNFAIP8L3 | RORA | 0.683605 | 6 | 0 | 6 |
| TNFAIP8L3 | ANGPTL1 | 0.680825 | 6 | 0 | 6 |
| TNFAIP8L3 | SLITRK3 | 0.680565 | 5 | 0 | 5 |
| TNFAIP8L3 | ANKRD31 | 0.678492 | 3 | 0 | 3 |
| TNFAIP8L3 | CYP4V2 | 0.674789 | 3 | 0 | 3 |
| TNFAIP8L3 | CASQ2 | 0.674412 | 6 | 0 | 6 |
| TNFAIP8L3 | FHL5 | 0.667753 | 5 | 0 | 4 |
| TNFAIP8L3 | TRPC6 | 0.66561 | 3 | 0 | 3 |
| TNFAIP8L3 | TSPYL1 | 0.664871 | 4 | 0 | 4 |
| TNFAIP8L3 | HOXA4 | 0.664738 | 3 | 0 | 3 |
For details and further investigation, click here
