Full name: CD14 molecule	Alias Symbol:
Type: protein-coding gene	Cytoband: 5q31.3
Entrez ID: 929	HGNC ID: HGNC:1628	Ensembl Gene: ENSG00000170458	OMIM ID: 158120
Drug and gene relationship at DGIdb

---

 

CD14 involved pathways:

KEGG pathway	Description	View
hsa04010	MAPK signaling pathway	View
hsa04064	NF-kappa B signaling pathway	View
hsa04620	Toll-like receptor signaling pathway	View
hsa04810	Regulation of actin cytoskeleton	View
hsa05130	Pathogenic Escherichia coli infection	View
hsa05132	Salmonella infection	View
hsa05134	Legionellosis	View
hsa05152	Tuberculosis	View

---

 

Expression of CD14:

 

Dataset	Gene	EntrezID	Probe	Log2FC	Adj.pValue	Expression
GSE17351	CD14	929	201743_at	0.8710	0.4969	Show
GSE20347	CD14	929	201743_at	0.5800	0.0107	Show
GSE23400	CD14	929	201743_at	0.5617	0.0000	Show
GSE26886	CD14	929	201743_at	0.7249	0.1265	Show
GSE29001	CD14	929	201743_at	0.9914	0.0170	Show
GSE38129	CD14	929	201743_at	0.6172	0.0465	Show
GSE45670	CD14	929	201743_at	-0.1206	0.7621	Show
GSE53622	CD14	929	7942	0.8847	0.0000	Show
GSE53624	CD14	929	7942	1.2721	0.0000	Show
GSE63941	CD14	929	201743_at	-1.6751	0.0739	Show
GSE77861	CD14	929	201743_at	0.9949	0.0021	Show
GSE97050	CD14	929	A_33_P3284508	1.0992	0.1090	Show
SRP007169	CD14	929	RNAseq	2.3029	0.0006	Show
SRP008496	CD14	929	RNAseq	1.8285	0.0001	Show
SRP064894	CD14	929	RNAseq	0.8174	0.0104	Show
SRP133303	CD14	929	RNAseq	0.9884	0.0032	Show
SRP159526	CD14	929	RNAseq	0.9832	0.0357	Show
SRP193095	CD14	929	RNAseq	1.8324	0.0000	Show
SRP219564	CD14	929	RNAseq	1.3541	0.0996	Show
TCGA	CD14	929	RNAseq	0.3394	0.0027	Show

Upregulated datasets: 4; Downregulated datasets: 0.  Download Data

---

 

Survival by CD14 expression:

 

---

Copy number change of CD14:

 

Dataset	Gene	EntrezID	Gain	Loss	Normal	Detail
GSE15526	CD14	929	3	11	16	Show
GSE20123	CD14	929	4	11	15	Show
GSE43470	CD14	929	2	10	31	Show
GSE46452	CD14	929	0	27	32	Show
GSE47630	CD14	929	0	20	20	Show
GSE54993	CD14	929	9	1	60	Show
GSE54994	CD14	929	2	14	37	Show
GSE60625	CD14	929	0	0	11	Show
GSE74703	CD14	929	2	7	27	Show
GSE74704	CD14	929	3	5	12	Show
TCGA	CD14	929	4	37	55	Show

Total number of gains: 29; Total number of losses: 143; Total Number of normals: 316.  Download Data

---

 

Somatic mutations of CD14:

 

---

 

Highly correlated genes for CD14:

 

Showing top 20/1343 corelated genes with mean PCC>0.5.

Gene1	Gene2	Mean PCC	Num. Datasets	Num. PCC<0	Num. PCC>0.5
CD14	C1QB	0.844271	12	0	12
CD14	FCGR3A	0.844182	3	0	3
CD14	TYROBP	0.834505	12	0	12
CD14	C1QA	0.822835	12	0	12
CD14	LRRC8C	0.80579	3	0	3
CD14	GPR153	0.804487	3	0	3
CD14	C3AR1	0.800846	11	0	10
CD14	PDIA5	0.796621	3	0	3
CD14	FCGR2A	0.79354	12	0	12
CD14	SMC6	0.780178	3	0	3
CD14	CERKL	0.753482	3	0	3
CD14	TNFRSF8	0.747716	3	0	3
CD14	C1QC	0.74395	8	0	8
CD14	WDR81	0.741605	3	0	3
CD14	C19orf38	0.739796	3	0	3
CD14	MED10	0.730513	4	0	3
CD14	MS4A4A	0.729537	11	0	10
CD14	SH3PXD2B	0.726978	6	0	6
CD14	LAPTM5	0.72668	12	0	12
CD14	RAB34	0.726063	3	0	3

For details and further investigation, click here