| Full name: ornithine decarboxylase antizyme 1 | Alias Symbol: AZI|MGC138338|AZ1 | ||
| Type: protein-coding gene | Cytoband: 19p13.3 | ||
| Entrez ID: 4946 | HGNC ID: HGNC:8095 | Ensembl Gene: ENSG00000104904 | OMIM ID: 601579 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of OAZ1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | OAZ1 | 4946 | 200077_s_at | 0.2868 | 0.1068 | |
| GSE20347 | OAZ1 | 4946 | 200077_s_at | 0.4036 | 0.0000 | |
| GSE23400 | OAZ1 | 4946 | 200077_s_at | 0.3293 | 0.0000 | |
| GSE26886 | OAZ1 | 4946 | 200077_s_at | 0.0035 | 0.9797 | |
| GSE29001 | OAZ1 | 4946 | 200077_s_at | 0.0539 | 0.8619 | |
| GSE38129 | OAZ1 | 4946 | 200077_s_at | 0.3732 | 0.0000 | |
| GSE45670 | OAZ1 | 4946 | 200077_s_at | 0.2502 | 0.0049 | |
| GSE53622 | OAZ1 | 4946 | 55111 | 0.1062 | 0.0281 | |
| GSE53624 | OAZ1 | 4946 | 55111 | 0.5425 | 0.0000 | |
| GSE63941 | OAZ1 | 4946 | 200077_s_at | -0.2854 | 0.0324 | |
| GSE77861 | OAZ1 | 4946 | 200077_s_at | 0.2426 | 0.0864 | |
| GSE97050 | OAZ1 | 4946 | A_23_P409951 | 0.0496 | 0.8795 | |
| SRP007169 | OAZ1 | 4946 | RNAseq | -0.8596 | 0.0111 | |
| SRP008496 | OAZ1 | 4946 | RNAseq | -0.7463 | 0.0005 | |
| SRP064894 | OAZ1 | 4946 | RNAseq | 0.2035 | 0.4289 | |
| SRP133303 | OAZ1 | 4946 | RNAseq | 0.2484 | 0.0869 | |
| SRP159526 | OAZ1 | 4946 | RNAseq | 0.0325 | 0.8709 | |
| SRP193095 | OAZ1 | 4946 | RNAseq | 0.0237 | 0.8555 | |
| SRP219564 | OAZ1 | 4946 | RNAseq | 0.1842 | 0.6045 | |
| TCGA | OAZ1 | 4946 | RNAseq | 0.0460 | 0.2311 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by OAZ1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of OAZ1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | OAZ1 | 4946 | 4 | 5 | 21 | |
| GSE20123 | OAZ1 | 4946 | 4 | 4 | 22 | |
| GSE43470 | OAZ1 | 4946 | 1 | 10 | 32 | |
| GSE46452 | OAZ1 | 4946 | 47 | 1 | 11 | |
| GSE47630 | OAZ1 | 4946 | 5 | 7 | 28 | |
| GSE54993 | OAZ1 | 4946 | 16 | 3 | 51 | |
| GSE54994 | OAZ1 | 4946 | 8 | 15 | 30 | |
| GSE60625 | OAZ1 | 4946 | 9 | 0 | 2 | |
| GSE74703 | OAZ1 | 4946 | 1 | 7 | 28 | |
| GSE74704 | OAZ1 | 4946 | 2 | 3 | 15 | |
| TCGA | OAZ1 | 4946 | 6 | 24 | 66 |
Total number of gains: 103; Total number of losses: 79; Total Number of normals: 306.
Somatic mutations of OAZ1:
Generating mutation plots.
Highly correlated genes for OAZ1:
Showing top 20/624 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| OAZ1 | MRPL47 | 0.748669 | 5 | 0 | 5 |
| OAZ1 | TNFRSF1B | 0.744325 | 3 | 0 | 3 |
| OAZ1 | TBCCD1 | 0.720393 | 6 | 0 | 6 |
| OAZ1 | FBXO45 | 0.718759 | 3 | 0 | 3 |
| OAZ1 | ECT2 | 0.712796 | 7 | 0 | 6 |
| OAZ1 | C16orf74 | 0.703128 | 3 | 0 | 3 |
| OAZ1 | CLPTM1L | 0.682952 | 5 | 0 | 4 |
| OAZ1 | ATP1B3 | 0.679503 | 8 | 0 | 6 |
| OAZ1 | MYNN | 0.675908 | 6 | 0 | 6 |
| OAZ1 | DNAJB11 | 0.674931 | 6 | 0 | 5 |
| OAZ1 | TMEM138 | 0.674068 | 4 | 0 | 4 |
| OAZ1 | TIMMDC1 | 0.671912 | 3 | 0 | 3 |
| OAZ1 | EIF2B5 | 0.666435 | 7 | 0 | 5 |
| OAZ1 | ATP6V1C1 | 0.66556 | 8 | 0 | 8 |
| OAZ1 | HES6 | 0.664054 | 3 | 0 | 3 |
| OAZ1 | U2SURP | 0.663386 | 7 | 0 | 6 |
| OAZ1 | RIOK1 | 0.660173 | 4 | 0 | 4 |
| OAZ1 | IFRD2 | 0.656421 | 3 | 0 | 3 |
| OAZ1 | PARL | 0.655425 | 9 | 0 | 9 |
| OAZ1 | LRRC58 | 0.653361 | 4 | 0 | 3 |
For details and further investigation, click here
