| Full name: transportin 3 | Alias Symbol: TRN-SR|MTR10A|TRN-SR2|IPO12 | ||
| Type: protein-coding gene | Cytoband: 7q32.1 | ||
| Entrez ID: 23534 | HGNC ID: HGNC:17103 | Ensembl Gene: ENSG00000064419 | OMIM ID: 610032 |
| Drug and gene relationship at DGIdb | |||
Expression of TNPO3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TNPO3 | 23534 | 212318_at | 0.0040 | 0.9954 | |
| GSE20347 | TNPO3 | 23534 | 212318_at | 0.2282 | 0.0993 | |
| GSE23400 | TNPO3 | 23534 | 212318_at | 0.0747 | 0.2414 | |
| GSE26886 | TNPO3 | 23534 | 212318_at | -0.1662 | 0.5757 | |
| GSE29001 | TNPO3 | 23534 | 212318_at | -0.0429 | 0.9132 | |
| GSE38129 | TNPO3 | 23534 | 212318_at | 0.2284 | 0.0592 | |
| GSE45670 | TNPO3 | 23534 | 212318_at | 0.1517 | 0.3862 | |
| GSE53622 | TNPO3 | 23534 | 7977 | -0.1426 | 0.0079 | |
| GSE53624 | TNPO3 | 23534 | 7977 | 0.1150 | 0.0451 | |
| GSE63941 | TNPO3 | 23534 | 212318_at | 0.6154 | 0.0914 | |
| GSE77861 | TNPO3 | 23534 | 212318_at | 0.3737 | 0.0158 | |
| GSE97050 | TNPO3 | 23534 | A_33_P3370132 | -0.1060 | 0.6916 | |
| SRP007169 | TNPO3 | 23534 | RNAseq | 0.6826 | 0.0566 | |
| SRP008496 | TNPO3 | 23534 | RNAseq | 0.3310 | 0.1340 | |
| SRP064894 | TNPO3 | 23534 | RNAseq | 0.2215 | 0.1143 | |
| SRP133303 | TNPO3 | 23534 | RNAseq | 0.2696 | 0.0531 | |
| SRP159526 | TNPO3 | 23534 | RNAseq | -0.2154 | 0.3060 | |
| SRP193095 | TNPO3 | 23534 | RNAseq | -0.1149 | 0.2078 | |
| SRP219564 | TNPO3 | 23534 | RNAseq | -0.3104 | 0.1792 | |
| TCGA | TNPO3 | 23534 | RNAseq | -0.0349 | 0.4632 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by TNPO3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TNPO3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TNPO3 | 23534 | 8 | 1 | 21 | |
| GSE20123 | TNPO3 | 23534 | 8 | 1 | 21 | |
| GSE43470 | TNPO3 | 23534 | 2 | 3 | 38 | |
| GSE46452 | TNPO3 | 23534 | 7 | 2 | 50 | |
| GSE47630 | TNPO3 | 23534 | 7 | 4 | 29 | |
| GSE54993 | TNPO3 | 23534 | 3 | 5 | 62 | |
| GSE54994 | TNPO3 | 23534 | 8 | 7 | 38 | |
| GSE60625 | TNPO3 | 23534 | 0 | 0 | 11 | |
| GSE74703 | TNPO3 | 23534 | 2 | 3 | 31 | |
| GSE74704 | TNPO3 | 23534 | 4 | 1 | 15 | |
| TCGA | TNPO3 | 23534 | 29 | 21 | 46 |
Total number of gains: 78; Total number of losses: 48; Total Number of normals: 362.
Somatic mutations of TNPO3:
Generating mutation plots.
Highly correlated genes for TNPO3:
Showing top 20/352 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TNPO3 | PTPN23 | 0.787042 | 3 | 0 | 3 |
| TNPO3 | SLC26A11 | 0.75951 | 3 | 0 | 3 |
| TNPO3 | PLXNB1 | 0.751556 | 3 | 0 | 3 |
| TNPO3 | PPP2R5E | 0.739786 | 3 | 0 | 3 |
| TNPO3 | ELOF1 | 0.736839 | 4 | 0 | 4 |
| TNPO3 | EXOC6 | 0.736112 | 3 | 0 | 3 |
| TNPO3 | ZBTB2 | 0.730037 | 3 | 0 | 3 |
| TNPO3 | ACAD9 | 0.723926 | 3 | 0 | 3 |
| TNPO3 | USP48 | 0.721383 | 3 | 0 | 3 |
| TNPO3 | WDTC1 | 0.720156 | 3 | 0 | 3 |
| TNPO3 | DGCR8 | 0.716955 | 3 | 0 | 3 |
| TNPO3 | PRR12 | 0.715918 | 3 | 0 | 3 |
| TNPO3 | INPP5E | 0.710468 | 4 | 0 | 4 |
| TNPO3 | EEF2 | 0.707614 | 3 | 0 | 3 |
| TNPO3 | LENG8 | 0.702616 | 3 | 0 | 3 |
| TNPO3 | GPBP1L1 | 0.697622 | 4 | 0 | 3 |
| TNPO3 | CRTC2 | 0.690322 | 4 | 0 | 4 |
| TNPO3 | SLC25A19 | 0.687561 | 3 | 0 | 3 |
| TNPO3 | BAG6 | 0.687406 | 5 | 0 | 5 |
| TNPO3 | ZNF765 | 0.687387 | 3 | 0 | 3 |
For details and further investigation, click here
