| Full name: mitochondrial ribosomal protein S10 | Alias Symbol: FLJ10567 | ||
| Type: protein-coding gene | Cytoband: 6p21.1 | ||
| Entrez ID: 55173 | HGNC ID: HGNC:14502 | Ensembl Gene: ENSG00000048544 | OMIM ID: 611976 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of MRPS10:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | MRPS10 | 55173 | 218106_s_at | -0.0699 | 0.9121 | |
| GSE20347 | MRPS10 | 55173 | 218106_s_at | -0.5966 | 0.0000 | |
| GSE23400 | MRPS10 | 55173 | 218106_s_at | -0.2412 | 0.0060 | |
| GSE26886 | MRPS10 | 55173 | 218106_s_at | -0.4084 | 0.0115 | |
| GSE29001 | MRPS10 | 55173 | 218106_s_at | -0.4738 | 0.0428 | |
| GSE38129 | MRPS10 | 55173 | 218106_s_at | -0.2775 | 0.0341 | |
| GSE45670 | MRPS10 | 55173 | 218106_s_at | -0.1555 | 0.3736 | |
| GSE53622 | MRPS10 | 55173 | 108591 | -0.5432 | 0.0000 | |
| GSE53624 | MRPS10 | 55173 | 108591 | -0.4493 | 0.0000 | |
| GSE63941 | MRPS10 | 55173 | 218106_s_at | 0.0106 | 0.9815 | |
| GSE77861 | MRPS10 | 55173 | 222522_x_at | -1.0617 | 0.0034 | |
| GSE97050 | MRPS10 | 55173 | A_24_P209285 | -0.3367 | 0.1839 | |
| SRP007169 | MRPS10 | 55173 | RNAseq | -1.8148 | 0.0000 | |
| SRP008496 | MRPS10 | 55173 | RNAseq | -1.8542 | 0.0000 | |
| SRP064894 | MRPS10 | 55173 | RNAseq | -1.0153 | 0.0000 | |
| SRP133303 | MRPS10 | 55173 | RNAseq | -0.2780 | 0.0684 | |
| SRP159526 | MRPS10 | 55173 | RNAseq | -0.9410 | 0.0000 | |
| SRP193095 | MRPS10 | 55173 | RNAseq | -0.9643 | 0.0000 | |
| SRP219564 | MRPS10 | 55173 | RNAseq | -0.7981 | 0.0319 | |
| TCGA | MRPS10 | 55173 | RNAseq | 0.1050 | 0.0396 |
Upregulated datasets: 0; Downregulated datasets: 4.
Survival by MRPS10 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of MRPS10:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | MRPS10 | 55173 | 7 | 0 | 23 | |
| GSE20123 | MRPS10 | 55173 | 7 | 0 | 23 | |
| GSE43470 | MRPS10 | 55173 | 6 | 0 | 37 | |
| GSE46452 | MRPS10 | 55173 | 2 | 9 | 48 | |
| GSE47630 | MRPS10 | 55173 | 8 | 4 | 28 | |
| GSE54993 | MRPS10 | 55173 | 3 | 2 | 65 | |
| GSE54994 | MRPS10 | 55173 | 11 | 4 | 38 | |
| GSE60625 | MRPS10 | 55173 | 0 | 1 | 10 | |
| GSE74703 | MRPS10 | 55173 | 6 | 0 | 30 | |
| GSE74704 | MRPS10 | 55173 | 3 | 0 | 17 | |
| TCGA | MRPS10 | 55173 | 20 | 13 | 63 |
Total number of gains: 73; Total number of losses: 33; Total Number of normals: 382.
Somatic mutations of MRPS10:
Generating mutation plots.
Highly correlated genes for MRPS10:
Showing top 20/1305 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| MRPS10 | PCBD2 | 0.765979 | 3 | 0 | 3 |
| MRPS10 | ALKBH7 | 0.759377 | 3 | 0 | 3 |
| MRPS10 | SPPL3 | 0.757943 | 3 | 0 | 3 |
| MRPS10 | PPP2R5E | 0.731367 | 3 | 0 | 3 |
| MRPS10 | FBXL3 | 0.730387 | 3 | 0 | 3 |
| MRPS10 | NDUFA13 | 0.728019 | 4 | 0 | 4 |
| MRPS10 | CCDC120 | 0.727172 | 3 | 0 | 3 |
| MRPS10 | FAM83D | 0.717315 | 5 | 0 | 4 |
| MRPS10 | EBPL | 0.714312 | 3 | 0 | 3 |
| MRPS10 | MKRN2 | 0.713356 | 5 | 0 | 5 |
| MRPS10 | SS18 | 0.712151 | 6 | 0 | 5 |
| MRPS10 | SH3GLB1 | 0.711739 | 8 | 0 | 7 |
| MRPS10 | TBC1D20 | 0.71167 | 3 | 0 | 3 |
| MRPS10 | SH3BP5 | 0.708549 | 3 | 0 | 3 |
| MRPS10 | ATG2B | 0.706864 | 3 | 0 | 3 |
| MRPS10 | TNRC6A | 0.705223 | 3 | 0 | 3 |
| MRPS10 | SH3BGRL | 0.703881 | 4 | 0 | 4 |
| MRPS10 | UNK | 0.701379 | 3 | 0 | 3 |
| MRPS10 | AK3 | 0.699128 | 4 | 0 | 4 |
| MRPS10 | BRK1 | 0.698308 | 5 | 0 | 4 |
For details and further investigation, click here
