| Full name: trinucleotide repeat containing adaptor 6B | Alias Symbol: KIAA1093 | ||
| Type: protein-coding gene | Cytoband: 22q13.1 | ||
| Entrez ID: 23112 | HGNC ID: HGNC:29190 | Ensembl Gene: ENSG00000100354 | OMIM ID: 610740 |
| Drug and gene relationship at DGIdb | |||
Expression of TNRC6B:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TNRC6B | 23112 | 1558142_at | -0.0452 | 0.9307 | |
| GSE20347 | TNRC6B | 23112 | 213254_at | -0.0968 | 0.3804 | |
| GSE23400 | TNRC6B | 23112 | 213254_at | 0.0066 | 0.9020 | |
| GSE26886 | TNRC6B | 23112 | 229036_at | -0.2225 | 0.1997 | |
| GSE29001 | TNRC6B | 23112 | 213254_at | 0.1086 | 0.6614 | |
| GSE38129 | TNRC6B | 23112 | 213254_at | -0.1044 | 0.2992 | |
| GSE45670 | TNRC6B | 23112 | 1558142_at | -0.3020 | 0.1420 | |
| GSE53622 | TNRC6B | 23112 | 30632 | 0.0556 | 0.4111 | |
| GSE53624 | TNRC6B | 23112 | 30632 | 0.2032 | 0.0000 | |
| GSE63941 | TNRC6B | 23112 | 1558142_at | -0.2692 | 0.5330 | |
| GSE77861 | TNRC6B | 23112 | 229036_at | 0.2488 | 0.1976 | |
| GSE97050 | TNRC6B | 23112 | A_23_P6490 | -0.1300 | 0.6722 | |
| SRP007169 | TNRC6B | 23112 | RNAseq | 1.2239 | 0.0029 | |
| SRP008496 | TNRC6B | 23112 | RNAseq | 0.8955 | 0.0001 | |
| SRP064894 | TNRC6B | 23112 | RNAseq | 0.1970 | 0.3119 | |
| SRP133303 | TNRC6B | 23112 | RNAseq | -0.1849 | 0.0271 | |
| SRP159526 | TNRC6B | 23112 | RNAseq | 0.4609 | 0.0188 | |
| SRP193095 | TNRC6B | 23112 | RNAseq | 0.1380 | 0.1559 | |
| SRP219564 | TNRC6B | 23112 | RNAseq | 0.2355 | 0.3750 | |
| TCGA | TNRC6B | 23112 | RNAseq | -0.0595 | 0.2150 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by TNRC6B expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TNRC6B:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TNRC6B | 23112 | 6 | 5 | 19 | |
| GSE20123 | TNRC6B | 23112 | 6 | 4 | 20 | |
| GSE43470 | TNRC6B | 23112 | 5 | 6 | 32 | |
| GSE46452 | TNRC6B | 23112 | 31 | 2 | 26 | |
| GSE47630 | TNRC6B | 23112 | 9 | 4 | 27 | |
| GSE54993 | TNRC6B | 23112 | 3 | 6 | 61 | |
| GSE54994 | TNRC6B | 23112 | 9 | 8 | 36 | |
| GSE60625 | TNRC6B | 23112 | 5 | 0 | 6 | |
| GSE74703 | TNRC6B | 23112 | 5 | 4 | 27 | |
| GSE74704 | TNRC6B | 23112 | 3 | 2 | 15 | |
| TCGA | TNRC6B | 23112 | 26 | 16 | 54 |
Total number of gains: 108; Total number of losses: 57; Total Number of normals: 323.
Somatic mutations of TNRC6B:
Generating mutation plots.
Highly correlated genes for TNRC6B:
Showing top 20/220 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TNRC6B | ZNF664 | 0.806131 | 3 | 0 | 3 |
| TNRC6B | FAM76B | 0.768323 | 3 | 0 | 3 |
| TNRC6B | GSTT1 | 0.734039 | 3 | 0 | 3 |
| TNRC6B | MYLIP | 0.731031 | 3 | 0 | 3 |
| TNRC6B | ZDHHC4 | 0.7303 | 3 | 0 | 3 |
| TNRC6B | ZNF175 | 0.72896 | 3 | 0 | 3 |
| TNRC6B | MKLN1 | 0.724876 | 3 | 0 | 3 |
| TNRC6B | LDOC1 | 0.724098 | 3 | 0 | 3 |
| TNRC6B | SP1 | 0.723339 | 3 | 0 | 3 |
| TNRC6B | INTS3 | 0.707749 | 3 | 0 | 3 |
| TNRC6B | MIPEP | 0.702366 | 3 | 0 | 3 |
| TNRC6B | BRI3 | 0.702047 | 3 | 0 | 3 |
| TNRC6B | PDE9A | 0.70015 | 3 | 0 | 3 |
| TNRC6B | TSPAN3 | 0.69931 | 3 | 0 | 3 |
| TNRC6B | SOS1 | 0.699302 | 4 | 0 | 3 |
| TNRC6B | COPS7A | 0.695957 | 3 | 0 | 3 |
| TNRC6B | TRIM21 | 0.69412 | 3 | 0 | 3 |
| TNRC6B | ZSWIM5 | 0.693043 | 3 | 0 | 3 |
| TNRC6B | TFIP11 | 0.692121 | 3 | 0 | 3 |
| TNRC6B | CSRNP2 | 0.687781 | 4 | 0 | 3 |
For details and further investigation, click here
