| Full name: glutathione S-transferase theta 1 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 22q11.23 alternate reference locus | ||
| Entrez ID: 2952 | HGNC ID: HGNC:4641 | Ensembl Gene: ENSG00000277656 | OMIM ID: 600436 |
| Drug and gene relationship at DGIdb | |||
Expression of GSTT1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | GSTT1 | 2952 | 203815_at | -0.6291 | 0.8087 | |
| GSE20347 | GSTT1 | 2952 | 203815_at | -0.5569 | 0.2284 | |
| GSE23400 | GSTT1 | 2952 | 203815_at | -0.5356 | 0.0018 | |
| GSE26886 | GSTT1 | 2952 | 203815_at | -0.6420 | 0.4195 | |
| GSE29001 | GSTT1 | 2952 | 203815_at | -0.3262 | 0.5814 | |
| GSE38129 | GSTT1 | 2952 | 203815_at | -0.7129 | 0.1544 | |
| GSE45670 | GSTT1 | 2952 | 203815_at | -1.2917 | 0.0594 | |
| GSE63941 | GSTT1 | 2952 | 203815_at | 0.7453 | 0.6740 | |
| GSE77861 | GSTT1 | 2952 | 203815_at | -0.3312 | 0.6203 | |
| GSE97050 | GSTT1 | 2952 | A_23_P254944 | -0.4801 | 0.1163 | |
| SRP133303 | GSTT1 | 2952 | RNAseq | -1.2004 | 0.1021 | |
| TCGA | GSTT1 | 2952 | RNAseq | -0.8508 | 0.2000 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by GSTT1 expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of GSTT1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | GSTT1 | 2952 | 5 | 7 | 18 | |
| GSE20123 | GSTT1 | 2952 | 5 | 6 | 19 | |
| GSE43470 | GSTT1 | 2952 | 3 | 6 | 34 | |
| GSE46452 | GSTT1 | 2952 | 32 | 1 | 26 | |
| GSE47630 | GSTT1 | 2952 | 8 | 5 | 27 | |
| GSE54993 | GSTT1 | 2952 | 3 | 6 | 61 | |
| GSE54994 | GSTT1 | 2952 | 11 | 7 | 35 | |
| GSE60625 | GSTT1 | 2952 | 5 | 0 | 6 | |
| GSE74703 | GSTT1 | 2952 | 3 | 5 | 28 | |
| GSE74704 | GSTT1 | 2952 | 2 | 3 | 15 | |
| TCGA | GSTT1 | 2952 | 26 | 15 | 55 |
Total number of gains: 103; Total number of losses: 61; Total Number of normals: 324.
Somatic mutations of GSTT1:
Generating mutation plots.
Highly correlated genes for GSTT1:
Showing top 20/45 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| GSTT1 | MLLT3 | 0.777524 | 3 | 0 | 3 |
| GSTT1 | TNRC6B | 0.734039 | 3 | 0 | 3 |
| GSTT1 | ATP6V0E2 | 0.730068 | 3 | 0 | 3 |
| GSTT1 | AFF3 | 0.726229 | 3 | 0 | 3 |
| GSTT1 | HERC1 | 0.725779 | 3 | 0 | 3 |
| GSTT1 | MAP2K6 | 0.709292 | 3 | 0 | 3 |
| GSTT1 | RGMB | 0.703929 | 3 | 0 | 3 |
| GSTT1 | MAOB | 0.701882 | 3 | 0 | 3 |
| GSTT1 | DTNA | 0.675816 | 3 | 0 | 3 |
| GSTT1 | CBX7 | 0.669829 | 4 | 0 | 3 |
| GSTT1 | KAT5 | 0.665486 | 3 | 0 | 3 |
| GSTT1 | ITPR1 | 0.664738 | 3 | 0 | 3 |
| GSTT1 | FAM124A | 0.660371 | 3 | 0 | 3 |
| GSTT1 | USP9X | 0.658206 | 4 | 0 | 3 |
| GSTT1 | CAPN7 | 0.656849 | 3 | 0 | 3 |
| GSTT1 | USP20 | 0.647611 | 3 | 0 | 3 |
| GSTT1 | SELENBP1 | 0.645579 | 4 | 0 | 3 |
| GSTT1 | LMO4 | 0.645549 | 4 | 0 | 3 |
| GSTT1 | PLCE1 | 0.638494 | 3 | 0 | 3 |
| GSTT1 | AKT3 | 0.637224 | 4 | 0 | 3 |
For details and further investigation, click here
