| Full name: BEN domain containing 6 | Alias Symbol: FLJ30162|bA203B9.1 | ||
| Type: protein-coding gene | Cytoband: 6p12.1 | ||
| Entrez ID: 221336 | HGNC ID: HGNC:20871 | Ensembl Gene: ENSG00000151917 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of BEND6:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | BEND6 | 221336 | 231175_at | 0.5945 | 0.3859 | |
| GSE26886 | BEND6 | 221336 | 231175_at | 1.4629 | 0.0001 | |
| GSE45670 | BEND6 | 221336 | 231175_at | 0.0599 | 0.9248 | |
| GSE53622 | BEND6 | 221336 | 5487 | 1.0691 | 0.0000 | |
| GSE53624 | BEND6 | 221336 | 5487 | 1.5443 | 0.0000 | |
| GSE63941 | BEND6 | 221336 | 231175_at | -3.4182 | 0.0000 | |
| GSE77861 | BEND6 | 221336 | 1568820_a_at | -0.0369 | 0.6142 | |
| GSE97050 | BEND6 | 221336 | A_33_P3329769 | 0.3378 | 0.3003 | |
| SRP007169 | BEND6 | 221336 | RNAseq | 3.4503 | 0.0010 | |
| SRP064894 | BEND6 | 221336 | RNAseq | 0.9686 | 0.0001 | |
| SRP133303 | BEND6 | 221336 | RNAseq | 0.5738 | 0.0100 | |
| SRP159526 | BEND6 | 221336 | RNAseq | 0.7098 | 0.1227 | |
| SRP193095 | BEND6 | 221336 | RNAseq | 0.5654 | 0.0000 | |
| SRP219564 | BEND6 | 221336 | RNAseq | 0.6376 | 0.1957 | |
| TCGA | BEND6 | 221336 | RNAseq | 1.0763 | 0.0000 |
Upregulated datasets: 5; Downregulated datasets: 1.
Survival by BEND6 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of BEND6:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | BEND6 | 221336 | 8 | 2 | 20 | |
| GSE20123 | BEND6 | 221336 | 8 | 2 | 20 | |
| GSE43470 | BEND6 | 221336 | 5 | 0 | 38 | |
| GSE46452 | BEND6 | 221336 | 2 | 10 | 47 | |
| GSE47630 | BEND6 | 221336 | 7 | 5 | 28 | |
| GSE54993 | BEND6 | 221336 | 3 | 2 | 65 | |
| GSE54994 | BEND6 | 221336 | 9 | 4 | 40 | |
| GSE60625 | BEND6 | 221336 | 0 | 1 | 10 | |
| GSE74703 | BEND6 | 221336 | 5 | 0 | 31 | |
| GSE74704 | BEND6 | 221336 | 4 | 1 | 15 | |
| TCGA | BEND6 | 221336 | 24 | 10 | 62 |
Total number of gains: 75; Total number of losses: 37; Total Number of normals: 376.
Somatic mutations of BEND6:
Generating mutation plots.
Highly correlated genes for BEND6:
Showing top 20/456 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| BEND6 | TRIO | 0.723324 | 5 | 0 | 5 |
| BEND6 | B3GNT9 | 0.715685 | 6 | 0 | 6 |
| BEND6 | LPCAT1 | 0.710019 | 5 | 0 | 4 |
| BEND6 | ANXA5 | 0.691031 | 5 | 0 | 5 |
| BEND6 | PFN2 | 0.682761 | 4 | 0 | 4 |
| BEND6 | FKBP9 | 0.681978 | 5 | 0 | 5 |
| BEND6 | PGM2L1 | 0.681649 | 3 | 0 | 3 |
| BEND6 | LHFPL2 | 0.678944 | 6 | 0 | 5 |
| BEND6 | MCOLN2 | 0.67752 | 3 | 0 | 3 |
| BEND6 | GALNT10 | 0.671668 | 6 | 0 | 6 |
| BEND6 | PLEKHA4 | 0.671563 | 3 | 0 | 3 |
| BEND6 | VOPP1 | 0.671371 | 5 | 0 | 4 |
| BEND6 | ADAMTS12 | 0.67052 | 6 | 0 | 5 |
| BEND6 | DPY19L1 | 0.668926 | 6 | 0 | 5 |
| BEND6 | CTHRC1 | 0.667179 | 8 | 0 | 7 |
| BEND6 | TMEM104 | 0.664944 | 4 | 0 | 4 |
| BEND6 | LAMB1 | 0.664557 | 7 | 0 | 6 |
| BEND6 | ECE1 | 0.664182 | 4 | 0 | 4 |
| BEND6 | CBLB | 0.664033 | 3 | 0 | 3 |
| BEND6 | TWIST1 | 0.66352 | 6 | 0 | 6 |
For details and further investigation, click here
