| Full name: POU domain class 5, transcription factor 2 | Alias Symbol: SPRM-1|FLJ25680 | ||
| Type: protein-coding gene | Cytoband: 5q15 | ||
| Entrez ID: 134187 | HGNC ID: HGNC:26367 | Ensembl Gene: ENSG00000248483 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of POU5F2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | POU5F2 | 134187 | 1553325_at | 0.2340 | 0.3636 | |
| GSE26886 | POU5F2 | 134187 | 1553325_at | 0.0069 | 0.9678 | |
| GSE45670 | POU5F2 | 134187 | 1553325_at | 0.1095 | 0.2069 | |
| GSE53622 | POU5F2 | 134187 | 69133 | -0.0002 | 0.9989 | |
| GSE53624 | POU5F2 | 134187 | 69133 | -0.3372 | 0.0029 | |
| GSE63941 | POU5F2 | 134187 | 1553325_at | 0.0750 | 0.5820 | |
| GSE77861 | POU5F2 | 134187 | 1553325_at | 0.1048 | 0.3063 | |
| GSE97050 | POU5F2 | 134187 | A_23_P358564 | 0.2058 | 0.2858 | |
| SRP007169 | POU5F2 | 134187 | RNAseq | 0.3929 | 0.5062 | |
| SRP064894 | POU5F2 | 134187 | RNAseq | 0.3775 | 0.2452 | |
| SRP133303 | POU5F2 | 134187 | RNAseq | -0.0650 | 0.6623 | |
| SRP159526 | POU5F2 | 134187 | RNAseq | 0.4739 | 0.2972 | |
| SRP193095 | POU5F2 | 134187 | RNAseq | -0.2321 | 0.1447 | |
| SRP219564 | POU5F2 | 134187 | RNAseq | -0.1030 | 0.8431 | |
| TCGA | POU5F2 | 134187 | RNAseq | 0.5226 | 0.4347 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by POU5F2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of POU5F2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | POU5F2 | 134187 | 1 | 13 | 16 | |
| GSE20123 | POU5F2 | 134187 | 1 | 13 | 16 | |
| GSE43470 | POU5F2 | 134187 | 2 | 10 | 31 | |
| GSE46452 | POU5F2 | 134187 | 1 | 27 | 31 | |
| GSE47630 | POU5F2 | 134187 | 1 | 21 | 18 | |
| GSE54993 | POU5F2 | 134187 | 8 | 1 | 61 | |
| GSE54994 | POU5F2 | 134187 | 1 | 18 | 34 | |
| GSE60625 | POU5F2 | 134187 | 0 | 0 | 11 | |
| GSE74703 | POU5F2 | 134187 | 1 | 8 | 27 | |
| GSE74704 | POU5F2 | 134187 | 1 | 7 | 12 | |
| TCGA | POU5F2 | 134187 | 3 | 48 | 45 |
Total number of gains: 20; Total number of losses: 166; Total Number of normals: 302.
Somatic mutations of POU5F2:
Generating mutation plots.
Highly correlated genes for POU5F2:
Showing top 20/96 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| POU5F2 | POP7 | 0.792858 | 3 | 0 | 3 |
| POU5F2 | EPHB4 | 0.775353 | 3 | 0 | 3 |
| POU5F2 | LEF1 | 0.765156 | 3 | 0 | 3 |
| POU5F2 | LAMP3 | 0.731523 | 3 | 0 | 3 |
| POU5F2 | OCIAD2 | 0.721869 | 3 | 0 | 3 |
| POU5F2 | ENTPD4 | 0.703252 | 3 | 0 | 3 |
| POU5F2 | EPCAM | 0.699331 | 3 | 0 | 3 |
| POU5F2 | RPS6KA1 | 0.698455 | 3 | 0 | 3 |
| POU5F2 | TMEM132A | 0.696247 | 3 | 0 | 3 |
| POU5F2 | UBE2T | 0.693443 | 3 | 0 | 3 |
| POU5F2 | SLC30A7 | 0.692246 | 3 | 0 | 3 |
| POU5F2 | BMP1 | 0.684839 | 3 | 0 | 3 |
| POU5F2 | ECE1 | 0.681665 | 3 | 0 | 3 |
| POU5F2 | NTRK2 | 0.675722 | 3 | 0 | 3 |
| POU5F2 | SYNGR2 | 0.668511 | 3 | 0 | 3 |
| POU5F2 | FCGR2A | 0.664989 | 3 | 0 | 3 |
| POU5F2 | FANCI | 0.664499 | 3 | 0 | 3 |
| POU5F2 | ADPGK | 0.662544 | 3 | 0 | 3 |
| POU5F2 | TPST1 | 0.658148 | 3 | 0 | 3 |
| POU5F2 | COTL1 | 0.657397 | 3 | 0 | 3 |
For details and further investigation, click here
