RAD23B

 

Full name: RAD23 homolog B, nucleotide excision repair protein Alias Symbol: HHR23B|P58|HR23B
Type: protein-coding gene Cytoband: 9q31.2
Entrez ID: 5887 HGNC ID: HGNC:9813 Ensembl Gene: ENSG00000119318 OMIM ID: 600062
Drug and gene relationship at DGIdb

 

Expression of RAD23B:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 RAD23B 5887 201222_s_at -0.1986 0.5204
GSE20347 RAD23B 5887 201223_s_at -0.3276 0.0274
GSE23400 RAD23B 5887 201222_s_at 0.0865 0.3738
GSE26886 RAD23B 5887 201222_s_at -0.7971 0.0002
GSE29001 RAD23B 5887 201223_s_at -0.0605 0.8142
GSE38129 RAD23B 5887 201223_s_at -0.1299 0.2645
GSE45670 RAD23B 5887 201222_s_at 0.0657 0.5420
GSE53622 RAD23B 5887 50138 -0.0808 0.1872
GSE53624 RAD23B 5887 50138 0.3109 0.0000
GSE63941 RAD23B 5887 201222_s_at 1.6929 0.0000
GSE77861 RAD23B 5887 201222_s_at -0.1454 0.5558
GSE97050 RAD23B 5887 A_33_P3312039 -0.0328 0.9294
SRP007169 RAD23B 5887 RNAseq 0.6984 0.0436
SRP008496 RAD23B 5887 RNAseq 0.5461 0.0065
SRP064894 RAD23B 5887 RNAseq -0.0800 0.6498
SRP133303 RAD23B 5887 RNAseq 0.0738 0.6290
SRP159526 RAD23B 5887 RNAseq -0.3511 0.1116
SRP193095 RAD23B 5887 RNAseq -0.1212 0.4037
SRP219564 RAD23B 5887 RNAseq -0.4014 0.0400
TCGA RAD23B 5887 RNAseq 0.1486 0.0007

Upregulated datasets: 1; Downregulated datasets: 0.  


 

Survival by RAD23B expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  


Copy number change of RAD23B:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 RAD23B 5887 4 9 17
GSE20123 RAD23B 5887 5 8 17
GSE43470 RAD23B 5887 7 3 33
GSE46452 RAD23B 5887 6 13 40
GSE47630 RAD23B 5887 1 17 22
GSE54993 RAD23B 5887 3 3 64
GSE54994 RAD23B 5887 9 10 34
GSE60625 RAD23B 5887 0 0 11
GSE74703 RAD23B 5887 6 3 27
GSE74704 RAD23B 5887 2 6 12
TCGA RAD23B 5887 26 21 49

Total number of gains: 69; Total number of losses: 93; Total Number of normals: 326.  


 

Somatic mutations of RAD23B:

 

Generating mutation plots.

 

Highly correlated genes for RAD23B:

 

Showing top 20/499 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
RAD23BMTA30.806342303
RAD23BTRERF10.798224303
RAD23BMPZL30.77022404
RAD23BULK30.766351303
RAD23BPADI10.750555303
RAD23BMALT10.747484303
RAD23BGPS20.746487303
RAD23BTRIM60.741717303
RAD23BCNOT100.734074303
RAD23BPLEKHG10.72571303
RAD23BLDHD0.71778303
RAD23BSLC12A60.717693403
RAD23BLAMP20.715771403
RAD23BNRARP0.715409303
RAD23BSEMA4A0.714698303
RAD23BREPS10.71311303
RAD23BATG130.71304404
RAD23BRPS6KB10.712602404
RAD23BFAM71F20.710585303
RAD23BGRIA40.707831303

For details and further investigation, click here