| Full name: molybdenum cofactor synthesis 2 | Alias Symbol: MOCO1|MOCS2A|MOCS2B | ||
| Type: protein-coding gene | Cytoband: 5q11.2 | ||
| Entrez ID: 4338 | HGNC ID: HGNC:7193 | Ensembl Gene: ENSG00000164172 | OMIM ID: 603708 |
| Drug and gene relationship at DGIdb | |||
Expression of MOCS2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | MOCS2 | 4338 | 218212_s_at | -0.6688 | 0.1678 | |
| GSE20347 | MOCS2 | 4338 | 218212_s_at | -0.4394 | 0.0006 | |
| GSE23400 | MOCS2 | 4338 | 218212_s_at | -0.1099 | 0.1430 | |
| GSE26886 | MOCS2 | 4338 | 218212_s_at | -1.0610 | 0.0001 | |
| GSE29001 | MOCS2 | 4338 | 218212_s_at | 0.0520 | 0.8699 | |
| GSE38129 | MOCS2 | 4338 | 218212_s_at | -0.5576 | 0.0002 | |
| GSE45670 | MOCS2 | 4338 | 218212_s_at | -0.3608 | 0.0385 | |
| GSE53622 | MOCS2 | 4338 | 17344 | -0.5203 | 0.0000 | |
| GSE53624 | MOCS2 | 4338 | 17344 | -0.4744 | 0.0000 | |
| GSE63941 | MOCS2 | 4338 | 218212_s_at | -0.6346 | 0.2784 | |
| GSE77861 | MOCS2 | 4338 | 218212_s_at | -0.7000 | 0.0048 | |
| GSE97050 | MOCS2 | 4338 | A_23_P92967 | -0.5459 | 0.1949 | |
| SRP007169 | MOCS2 | 4338 | RNAseq | -0.2932 | 0.4098 | |
| SRP008496 | MOCS2 | 4338 | RNAseq | -0.5488 | 0.0309 | |
| SRP064894 | MOCS2 | 4338 | RNAseq | -0.3467 | 0.0089 | |
| SRP133303 | MOCS2 | 4338 | RNAseq | -0.1215 | 0.4756 | |
| SRP159526 | MOCS2 | 4338 | RNAseq | -0.1972 | 0.6369 | |
| SRP193095 | MOCS2 | 4338 | RNAseq | -0.6214 | 0.0000 | |
| SRP219564 | MOCS2 | 4338 | RNAseq | -0.5183 | 0.2616 | |
| TCGA | MOCS2 | 4338 | RNAseq | -0.2465 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by MOCS2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of MOCS2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | MOCS2 | 4338 | 1 | 12 | 17 | |
| GSE20123 | MOCS2 | 4338 | 1 | 12 | 17 | |
| GSE43470 | MOCS2 | 4338 | 1 | 12 | 30 | |
| GSE46452 | MOCS2 | 4338 | 1 | 27 | 31 | |
| GSE47630 | MOCS2 | 4338 | 2 | 16 | 22 | |
| GSE54993 | MOCS2 | 4338 | 8 | 1 | 61 | |
| GSE54994 | MOCS2 | 4338 | 5 | 17 | 31 | |
| GSE60625 | MOCS2 | 4338 | 0 | 0 | 11 | |
| GSE74703 | MOCS2 | 4338 | 1 | 9 | 26 | |
| GSE74704 | MOCS2 | 4338 | 1 | 5 | 14 | |
| TCGA | MOCS2 | 4338 | 9 | 45 | 42 |
Total number of gains: 30; Total number of losses: 156; Total Number of normals: 302.
Somatic mutations of MOCS2:
Generating mutation plots.
Highly correlated genes for MOCS2:
Showing top 20/1140 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| MOCS2 | NDUFV3 | 0.76816 | 3 | 0 | 3 |
| MOCS2 | ANO8 | 0.737206 | 3 | 0 | 3 |
| MOCS2 | ZDHHC21 | 0.732986 | 3 | 0 | 3 |
| MOCS2 | ULK3 | 0.728485 | 3 | 0 | 3 |
| MOCS2 | PHLDB1 | 0.726995 | 3 | 0 | 3 |
| MOCS2 | TRIM33 | 0.724213 | 3 | 0 | 3 |
| MOCS2 | RAB27B | 0.720643 | 3 | 0 | 3 |
| MOCS2 | TYW3 | 0.717182 | 4 | 0 | 4 |
| MOCS2 | EPB41 | 0.711521 | 3 | 0 | 3 |
| MOCS2 | ZNF717 | 0.710489 | 4 | 0 | 3 |
| MOCS2 | MIER1 | 0.710389 | 4 | 0 | 3 |
| MOCS2 | CCDC159 | 0.709318 | 3 | 0 | 3 |
| MOCS2 | ZNF823 | 0.707316 | 3 | 0 | 3 |
| MOCS2 | ICA1L | 0.706749 | 3 | 0 | 3 |
| MOCS2 | SMAP1 | 0.705821 | 4 | 0 | 4 |
| MOCS2 | REEP5 | 0.705495 | 4 | 0 | 4 |
| MOCS2 | CCNYL1 | 0.705417 | 4 | 0 | 3 |
| MOCS2 | TMEM219 | 0.70105 | 4 | 0 | 3 |
| MOCS2 | GAB1 | 0.700665 | 8 | 0 | 7 |
| MOCS2 | AP3S2 | 0.699688 | 3 | 0 | 3 |
For details and further investigation, click here
