| Full name: endosulfine alpha | Alias Symbol: MGC4319|MGC8394|MGC78563|ARPP-19e | ||
| Type: protein-coding gene | Cytoband: 1q21.3 | ||
| Entrez ID: 2029 | HGNC ID: HGNC:3360 | Ensembl Gene: ENSG00000143420 | OMIM ID: 603061 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of ENSA:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ENSA | 2029 | 202596_at | -0.1767 | 0.7114 | |
| GSE20347 | ENSA | 2029 | 202596_at | -0.7033 | 0.0000 | |
| GSE23400 | ENSA | 2029 | 202596_at | -0.3183 | 0.0001 | |
| GSE26886 | ENSA | 2029 | 202596_at | -0.9490 | 0.0002 | |
| GSE29001 | ENSA | 2029 | 202596_at | -0.5628 | 0.0226 | |
| GSE38129 | ENSA | 2029 | 202596_at | -0.3787 | 0.0254 | |
| GSE45670 | ENSA | 2029 | 202596_at | -0.1454 | 0.2576 | |
| GSE53622 | ENSA | 2029 | 115861 | -0.6289 | 0.0000 | |
| GSE53624 | ENSA | 2029 | 115861 | -0.8316 | 0.0000 | |
| GSE63941 | ENSA | 2029 | 202596_at | 1.0941 | 0.0045 | |
| GSE77861 | ENSA | 2029 | 202596_at | -0.4530 | 0.0110 | |
| GSE97050 | ENSA | 2029 | A_32_P107746 | -0.4023 | 0.2280 | |
| SRP007169 | ENSA | 2029 | RNAseq | -1.9384 | 0.0000 | |
| SRP008496 | ENSA | 2029 | RNAseq | -1.6069 | 0.0000 | |
| SRP064894 | ENSA | 2029 | RNAseq | -0.8158 | 0.0001 | |
| SRP133303 | ENSA | 2029 | RNAseq | -0.6011 | 0.0016 | |
| SRP159526 | ENSA | 2029 | RNAseq | -0.1661 | 0.5171 | |
| SRP193095 | ENSA | 2029 | RNAseq | -0.7384 | 0.0000 | |
| SRP219564 | ENSA | 2029 | RNAseq | -0.6283 | 0.0524 | |
| TCGA | ENSA | 2029 | RNAseq | -0.0022 | 0.9596 |
Upregulated datasets: 1; Downregulated datasets: 2.
Survival by ENSA expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ENSA:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ENSA | 2029 | 15 | 0 | 15 | |
| GSE20123 | ENSA | 2029 | 15 | 0 | 15 | |
| GSE43470 | ENSA | 2029 | 6 | 1 | 36 | |
| GSE46452 | ENSA | 2029 | 2 | 1 | 56 | |
| GSE47630 | ENSA | 2029 | 14 | 0 | 26 | |
| GSE54993 | ENSA | 2029 | 0 | 3 | 67 | |
| GSE54994 | ENSA | 2029 | 15 | 0 | 38 | |
| GSE60625 | ENSA | 2029 | 0 | 0 | 11 | |
| GSE74703 | ENSA | 2029 | 6 | 1 | 29 | |
| GSE74704 | ENSA | 2029 | 7 | 0 | 13 | |
| TCGA | ENSA | 2029 | 38 | 2 | 56 |
Total number of gains: 118; Total number of losses: 8; Total Number of normals: 362.
Somatic mutations of ENSA:
Generating mutation plots.
Highly correlated genes for ENSA:
Showing top 20/1177 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ENSA | GRHPR | 0.831287 | 3 | 0 | 3 |
| ENSA | SYNE2 | 0.803913 | 3 | 0 | 3 |
| ENSA | PURA | 0.757514 | 3 | 0 | 3 |
| ENSA | RGS14 | 0.736741 | 11 | 0 | 11 |
| ENSA | GLYR1 | 0.730315 | 3 | 0 | 3 |
| ENSA | DDI2 | 0.710282 | 3 | 0 | 3 |
| ENSA | ZNF740 | 0.70646 | 3 | 0 | 3 |
| ENSA | NUAK2 | 0.704997 | 3 | 0 | 3 |
| ENSA | ACOX1 | 0.703285 | 8 | 0 | 8 |
| ENSA | BTBD11 | 0.70319 | 5 | 0 | 5 |
| ENSA | DLD | 0.701614 | 3 | 0 | 3 |
| ENSA | RAB25 | 0.699892 | 13 | 0 | 12 |
| ENSA | PSMD6-AS2 | 0.699873 | 3 | 0 | 3 |
| ENSA | CCDC66 | 0.699488 | 3 | 0 | 3 |
| ENSA | ATF7 | 0.699386 | 4 | 0 | 3 |
| ENSA | TMEM79 | 0.697713 | 7 | 0 | 7 |
| ENSA | ALKBH8 | 0.696333 | 3 | 0 | 3 |
| ENSA | SNORA68 | 0.695723 | 3 | 0 | 3 |
| ENSA | TMEM54 | 0.695125 | 3 | 0 | 3 |
| ENSA | CXCL17 | 0.693106 | 6 | 0 | 6 |
For details and further investigation, click here
