| Full name: coiled-coil domain containing 66 | Alias Symbol: DKFZp686C0433 | ||
| Type: protein-coding gene | Cytoband: 3p14.3 | ||
| Entrez ID: 285331 | HGNC ID: HGNC:27709 | Ensembl Gene: ENSG00000180376 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of CCDC66:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CCDC66 | 285331 | 228122_at | -0.2013 | 0.4848 | |
| GSE26886 | CCDC66 | 285331 | 228122_at | -0.3039 | 0.0610 | |
| GSE45670 | CCDC66 | 285331 | 228122_at | -0.2701 | 0.0184 | |
| GSE53622 | CCDC66 | 285331 | 133165 | -0.3746 | 0.0000 | |
| GSE53624 | CCDC66 | 285331 | 133165 | -0.4088 | 0.0001 | |
| GSE63941 | CCDC66 | 285331 | 228122_at | -0.3857 | 0.3016 | |
| GSE77861 | CCDC66 | 285331 | 228122_at | -0.1559 | 0.3651 | |
| GSE97050 | CCDC66 | 285331 | A_23_P396981 | -0.3369 | 0.2458 | |
| SRP007169 | CCDC66 | 285331 | RNAseq | -0.0946 | 0.8898 | |
| SRP008496 | CCDC66 | 285331 | RNAseq | 0.4584 | 0.1803 | |
| SRP064894 | CCDC66 | 285331 | RNAseq | -0.1837 | 0.3482 | |
| SRP133303 | CCDC66 | 285331 | RNAseq | -0.3051 | 0.0356 | |
| SRP159526 | CCDC66 | 285331 | RNAseq | -0.0421 | 0.9027 | |
| SRP193095 | CCDC66 | 285331 | RNAseq | -0.2984 | 0.0148 | |
| SRP219564 | CCDC66 | 285331 | RNAseq | -0.1029 | 0.7894 | |
| TCGA | CCDC66 | 285331 | RNAseq | -0.2341 | 0.0006 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by CCDC66 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CCDC66:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CCDC66 | 285331 | 0 | 16 | 14 | |
| GSE20123 | CCDC66 | 285331 | 0 | 17 | 13 | |
| GSE43470 | CCDC66 | 285331 | 0 | 17 | 26 | |
| GSE46452 | CCDC66 | 285331 | 2 | 17 | 40 | |
| GSE47630 | CCDC66 | 285331 | 1 | 24 | 15 | |
| GSE54993 | CCDC66 | 285331 | 6 | 2 | 62 | |
| GSE54994 | CCDC66 | 285331 | 0 | 32 | 21 | |
| GSE60625 | CCDC66 | 285331 | 5 | 0 | 6 | |
| GSE74703 | CCDC66 | 285331 | 0 | 14 | 22 | |
| GSE74704 | CCDC66 | 285331 | 0 | 11 | 9 | |
| TCGA | CCDC66 | 285331 | 0 | 79 | 17 |
Total number of gains: 14; Total number of losses: 229; Total Number of normals: 245.
Somatic mutations of CCDC66:
Generating mutation plots.
Highly correlated genes for CCDC66:
Showing top 20/569 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CCDC66 | ZFYVE21 | 0.809793 | 3 | 0 | 3 |
| CCDC66 | ZNF273 | 0.738123 | 4 | 0 | 4 |
| CCDC66 | SENP6 | 0.735375 | 6 | 0 | 6 |
| CCDC66 | PPID | 0.729173 | 3 | 0 | 3 |
| CCDC66 | ZMPSTE24 | 0.726993 | 3 | 0 | 3 |
| CCDC66 | VPS29 | 0.72648 | 3 | 0 | 3 |
| CCDC66 | ZNF800 | 0.724454 | 3 | 0 | 3 |
| CCDC66 | REST | 0.720236 | 3 | 0 | 3 |
| CCDC66 | RIOK2 | 0.718915 | 3 | 0 | 3 |
| CCDC66 | TCF12 | 0.718377 | 3 | 0 | 3 |
| CCDC66 | THOC2 | 0.712308 | 3 | 0 | 3 |
| CCDC66 | TRIP4 | 0.705904 | 3 | 0 | 3 |
| CCDC66 | PPP2CB | 0.699729 | 3 | 0 | 3 |
| CCDC66 | ENSA | 0.699488 | 3 | 0 | 3 |
| CCDC66 | PTCD2 | 0.698564 | 3 | 0 | 3 |
| CCDC66 | PTPN21 | 0.696275 | 4 | 0 | 3 |
| CCDC66 | CNTNAP3 | 0.695417 | 3 | 0 | 3 |
| CCDC66 | BTBD7 | 0.694545 | 3 | 0 | 3 |
| CCDC66 | CUL1 | 0.694416 | 3 | 0 | 3 |
| CCDC66 | FBXW2 | 0.693174 | 4 | 0 | 3 |
For details and further investigation, click here
