| Full name: transient receptor potential cation channel subfamily V member 6 | Alias Symbol: CaT1 | ||
| Type: protein-coding gene | Cytoband: 7q34 | ||
| Entrez ID: 55503 | HGNC ID: HGNC:14006 | Ensembl Gene: ENSG00000165125 | OMIM ID: 606680 |
| Drug and gene relationship at DGIdb | |||
Expression of TRPV6:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TRPV6 | 55503 | 206827_s_at | -0.2296 | 0.3965 | |
| GSE20347 | TRPV6 | 55503 | 206827_s_at | -0.0962 | 0.2761 | |
| GSE23400 | TRPV6 | 55503 | 206827_s_at | -0.1526 | 0.0000 | |
| GSE26886 | TRPV6 | 55503 | 206827_s_at | -0.0103 | 0.9486 | |
| GSE29001 | TRPV6 | 55503 | 206827_s_at | -0.3666 | 0.0371 | |
| GSE38129 | TRPV6 | 55503 | 206827_s_at | -0.1670 | 0.1123 | |
| GSE45670 | TRPV6 | 55503 | 206827_s_at | -0.1872 | 0.0603 | |
| GSE53622 | TRPV6 | 55503 | 54077 | -0.4040 | 0.0000 | |
| GSE53624 | TRPV6 | 55503 | 54077 | -0.4574 | 0.0001 | |
| GSE63941 | TRPV6 | 55503 | 206827_s_at | 0.3609 | 0.3213 | |
| GSE77861 | TRPV6 | 55503 | 206827_s_at | -0.0699 | 0.5797 | |
| GSE97050 | TRPV6 | 55503 | A_33_P3364854 | -0.2018 | 0.4829 | |
| SRP064894 | TRPV6 | 55503 | RNAseq | -1.9622 | 0.0000 | |
| SRP133303 | TRPV6 | 55503 | RNAseq | -1.4833 | 0.0097 | |
| SRP159526 | TRPV6 | 55503 | RNAseq | -0.9193 | 0.2621 | |
| SRP193095 | TRPV6 | 55503 | RNAseq | -1.7297 | 0.0000 | |
| TCGA | TRPV6 | 55503 | RNAseq | -1.1840 | 0.0478 |
Upregulated datasets: 0; Downregulated datasets: 4.
Survival by TRPV6 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TRPV6:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TRPV6 | 55503 | 4 | 2 | 24 | |
| GSE20123 | TRPV6 | 55503 | 4 | 2 | 24 | |
| GSE43470 | TRPV6 | 55503 | 2 | 4 | 37 | |
| GSE46452 | TRPV6 | 55503 | 7 | 2 | 50 | |
| GSE47630 | TRPV6 | 55503 | 6 | 7 | 27 | |
| GSE54993 | TRPV6 | 55503 | 3 | 4 | 63 | |
| GSE54994 | TRPV6 | 55503 | 5 | 8 | 40 | |
| GSE60625 | TRPV6 | 55503 | 0 | 0 | 11 | |
| GSE74703 | TRPV6 | 55503 | 2 | 4 | 30 | |
| GSE74704 | TRPV6 | 55503 | 2 | 2 | 16 | |
| TCGA | TRPV6 | 55503 | 28 | 23 | 45 |
Total number of gains: 63; Total number of losses: 58; Total Number of normals: 367.
Somatic mutations of TRPV6:
Generating mutation plots.
Highly correlated genes for TRPV6:
Showing top 20/387 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TRPV6 | LINC00163 | 0.704092 | 3 | 0 | 3 |
| TRPV6 | CECR9 | 0.679788 | 3 | 0 | 3 |
| TRPV6 | IGH | 0.654694 | 6 | 0 | 6 |
| TRPV6 | KRT20 | 0.643537 | 3 | 0 | 3 |
| TRPV6 | SFRP5 | 0.641431 | 6 | 0 | 4 |
| TRPV6 | CLDND2 | 0.641205 | 3 | 0 | 3 |
| TRPV6 | TPRN | 0.641001 | 4 | 0 | 3 |
| TRPV6 | MYBPC3 | 0.640471 | 6 | 0 | 6 |
| TRPV6 | IL5 | 0.638159 | 5 | 0 | 5 |
| TRPV6 | SMAGP | 0.637246 | 5 | 0 | 4 |
| TRPV6 | C2orf50 | 0.635414 | 3 | 0 | 3 |
| TRPV6 | DEGS2 | 0.6337 | 3 | 0 | 3 |
| TRPV6 | ELAVL3 | 0.633011 | 7 | 0 | 5 |
| TRPV6 | TUB | 0.631063 | 4 | 0 | 4 |
| TRPV6 | CLDN6 | 0.62883 | 8 | 0 | 7 |
| TRPV6 | IGSF22 | 0.628742 | 3 | 0 | 3 |
| TRPV6 | RPRML | 0.628037 | 3 | 0 | 3 |
| TRPV6 | FAM180B | 0.627834 | 3 | 0 | 3 |
| TRPV6 | PIGR | 0.627833 | 3 | 0 | 3 |
| TRPV6 | AMN | 0.627522 | 7 | 0 | 6 |
For details and further investigation, click here
