| Full name: nuclear cap binding protein subunit 2 | Alias Symbol: NIP1|CBP20|Cbc2 | ||
| Type: protein-coding gene | Cytoband: 3q29 | ||
| Entrez ID: 22916 | HGNC ID: HGNC:7659 | Ensembl Gene: ENSG00000114503 | OMIM ID: 605133 |
| Drug and gene relationship at DGIdb | |||
Expression of NCBP2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | NCBP2 | 22916 | 201517_at | 0.7915 | 0.0515 | |
| GSE20347 | NCBP2 | 22916 | 201517_at | 0.9081 | 0.0000 | |
| GSE23400 | NCBP2 | 22916 | 201517_at | 0.9383 | 0.0000 | |
| GSE26886 | NCBP2 | 22916 | 201517_at | 0.0994 | 0.6688 | |
| GSE29001 | NCBP2 | 22916 | 201517_at | 1.0687 | 0.0018 | |
| GSE38129 | NCBP2 | 22916 | 201517_at | 0.9070 | 0.0000 | |
| GSE45670 | NCBP2 | 22916 | 201517_at | 0.6553 | 0.0003 | |
| GSE53622 | NCBP2 | 22916 | 33491 | 0.8934 | 0.0000 | |
| GSE53624 | NCBP2 | 22916 | 33491 | 1.0458 | 0.0000 | |
| GSE63941 | NCBP2 | 22916 | 201517_at | 0.0415 | 0.9270 | |
| GSE77861 | NCBP2 | 22916 | 201517_at | 0.6731 | 0.0111 | |
| GSE97050 | NCBP2 | 22916 | A_24_P157424 | 0.1954 | 0.4507 | |
| SRP007169 | NCBP2 | 22916 | RNAseq | 1.7696 | 0.0000 | |
| SRP008496 | NCBP2 | 22916 | RNAseq | 2.0673 | 0.0000 | |
| SRP064894 | NCBP2 | 22916 | RNAseq | 0.8301 | 0.0000 | |
| SRP133303 | NCBP2 | 22916 | RNAseq | 1.2264 | 0.0000 | |
| SRP159526 | NCBP2 | 22916 | RNAseq | 1.2845 | 0.0000 | |
| SRP193095 | NCBP2 | 22916 | RNAseq | 0.6543 | 0.0000 | |
| SRP219564 | NCBP2 | 22916 | RNAseq | 0.5960 | 0.0882 | |
| TCGA | NCBP2 | 22916 | RNAseq | 0.2471 | 0.0000 |
Upregulated datasets: 6; Downregulated datasets: 0.
Survival by NCBP2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of NCBP2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | NCBP2 | 22916 | 22 | 0 | 8 | |
| GSE20123 | NCBP2 | 22916 | 22 | 0 | 8 | |
| GSE43470 | NCBP2 | 22916 | 21 | 0 | 22 | |
| GSE46452 | NCBP2 | 22916 | 20 | 1 | 38 | |
| GSE47630 | NCBP2 | 22916 | 27 | 2 | 11 | |
| GSE54993 | NCBP2 | 22916 | 1 | 22 | 47 | |
| GSE54994 | NCBP2 | 22916 | 41 | 0 | 12 | |
| GSE60625 | NCBP2 | 22916 | 0 | 6 | 5 | |
| GSE74703 | NCBP2 | 22916 | 19 | 0 | 17 | |
| GSE74704 | NCBP2 | 22916 | 14 | 0 | 6 | |
| TCGA | NCBP2 | 22916 | 76 | 1 | 19 |
Total number of gains: 263; Total number of losses: 32; Total Number of normals: 193.
Somatic mutations of NCBP2:
Generating mutation plots.
Highly correlated genes for NCBP2:
Showing top 20/1815 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| NCBP2 | RIOK1 | 0.814215 | 4 | 0 | 4 |
| NCBP2 | SLC39A3 | 0.811625 | 3 | 0 | 3 |
| NCBP2 | XRN1 | 0.79888 | 3 | 0 | 3 |
| NCBP2 | CRTC2 | 0.798094 | 3 | 0 | 3 |
| NCBP2 | PRRC2A | 0.796188 | 3 | 0 | 3 |
| NCBP2 | METAP1D | 0.789134 | 3 | 0 | 3 |
| NCBP2 | ALKBH6 | 0.787077 | 4 | 0 | 4 |
| NCBP2 | RBM26 | 0.781012 | 3 | 0 | 3 |
| NCBP2 | C12orf73 | 0.761542 | 3 | 0 | 3 |
| NCBP2 | U2SURP | 0.760928 | 9 | 0 | 8 |
| NCBP2 | LRRC58 | 0.759956 | 5 | 0 | 4 |
| NCBP2 | FXR1 | 0.756435 | 10 | 0 | 9 |
| NCBP2 | HMCES | 0.753609 | 7 | 0 | 7 |
| NCBP2 | TTC17 | 0.752493 | 3 | 0 | 3 |
| NCBP2 | MAP3K13 | 0.75224 | 5 | 0 | 4 |
| NCBP2 | SLC25A19 | 0.739599 | 3 | 0 | 3 |
| NCBP2 | NENF | 0.739206 | 4 | 0 | 4 |
| NCBP2 | RICTOR | 0.735589 | 3 | 0 | 3 |
| NCBP2 | RNF7 | 0.734988 | 11 | 0 | 10 |
| NCBP2 | FZD6 | 0.732515 | 10 | 0 | 9 |
For details and further investigation, click here
