| Full name: tubulin beta 1 class VI | Alias Symbol: dJ543J19.4 | ||
| Type: protein-coding gene | Cytoband: 20q13.32 | ||
| Entrez ID: 81027 | HGNC ID: HGNC:16257 | Ensembl Gene: ENSG00000101162 | OMIM ID: 612901 |
| Drug and gene relationship at DGIdb | |||
TUBB1 involved pathways:
| KEGG pathway | Description | View |
|---|---|---|
| hsa05130 | Pathogenic Escherichia coli infection |
Expression of TUBB1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TUBB1 | 81027 | 208601_s_at | -0.0562 | 0.8117 | |
| GSE20347 | TUBB1 | 81027 | 208601_s_at | -0.0522 | 0.2379 | |
| GSE23400 | TUBB1 | 81027 | 208601_s_at | -0.0867 | 0.0059 | |
| GSE26886 | TUBB1 | 81027 | 208601_s_at | 0.1693 | 0.0438 | |
| GSE29001 | TUBB1 | 81027 | 208601_s_at | -0.0484 | 0.5839 | |
| GSE38129 | TUBB1 | 81027 | 208601_s_at | -0.0897 | 0.0898 | |
| GSE45670 | TUBB1 | 81027 | 230690_at | 0.3376 | 0.3216 | |
| GSE63941 | TUBB1 | 81027 | 208601_s_at | 0.2103 | 0.1641 | |
| GSE77861 | TUBB1 | 81027 | 208601_s_at | 0.0370 | 0.7805 | |
| SRP133303 | TUBB1 | 81027 | RNAseq | -0.5932 | 0.1306 | |
| SRP193095 | TUBB1 | 81027 | RNAseq | 0.2134 | 0.0896 | |
| TCGA | TUBB1 | 81027 | RNAseq | -0.3784 | 0.0415 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by TUBB1 expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of TUBB1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TUBB1 | 81027 | 14 | 2 | 14 | |
| GSE20123 | TUBB1 | 81027 | 14 | 2 | 14 | |
| GSE43470 | TUBB1 | 81027 | 13 | 0 | 30 | |
| GSE46452 | TUBB1 | 81027 | 29 | 0 | 30 | |
| GSE47630 | TUBB1 | 81027 | 24 | 1 | 15 | |
| GSE54993 | TUBB1 | 81027 | 0 | 17 | 53 | |
| GSE54994 | TUBB1 | 81027 | 29 | 0 | 24 | |
| GSE60625 | TUBB1 | 81027 | 0 | 0 | 11 | |
| GSE74703 | TUBB1 | 81027 | 11 | 0 | 25 | |
| GSE74704 | TUBB1 | 81027 | 11 | 0 | 9 | |
| TCGA | TUBB1 | 81027 | 43 | 4 | 49 |
Total number of gains: 188; Total number of losses: 26; Total Number of normals: 274.
Somatic mutations of TUBB1:
Generating mutation plots.
Highly correlated genes for TUBB1:
Showing top 20/220 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TUBB1 | SARDH | 0.686793 | 3 | 0 | 3 |
| TUBB1 | ZNF483 | 0.667486 | 3 | 0 | 3 |
| TUBB1 | GABRR2 | 0.656216 | 4 | 0 | 4 |
| TUBB1 | AQP6 | 0.649844 | 3 | 0 | 3 |
| TUBB1 | CT55 | 0.633491 | 3 | 0 | 3 |
| TUBB1 | CDH15 | 0.632479 | 5 | 0 | 4 |
| TUBB1 | IFNA10 | 0.631092 | 3 | 0 | 3 |
| TUBB1 | PNLIPRP1 | 0.630978 | 4 | 0 | 3 |
| TUBB1 | GABRG3 | 0.630792 | 4 | 0 | 4 |
| TUBB1 | OR10J1 | 0.628862 | 4 | 0 | 4 |
| TUBB1 | FBP2 | 0.628485 | 4 | 0 | 4 |
| TUBB1 | TBX6 | 0.626321 | 4 | 0 | 4 |
| TUBB1 | ERBB4 | 0.617542 | 3 | 0 | 3 |
| TUBB1 | OR2J2 | 0.61732 | 4 | 0 | 3 |
| TUBB1 | NR2E3 | 0.615997 | 3 | 0 | 3 |
| TUBB1 | FTHL17 | 0.615691 | 3 | 0 | 3 |
| TUBB1 | TMEM59L | 0.610683 | 5 | 0 | 4 |
| TUBB1 | MAPK4 | 0.60358 | 4 | 0 | 3 |
| TUBB1 | RBP3 | 0.603368 | 5 | 0 | 5 |
| TUBB1 | CHRNA2 | 0.601157 | 4 | 0 | 3 |
For details and further investigation, click here
