| Full name: nuclear receptor subfamily 2 group E member 3 | Alias Symbol: PNR|rd7|RP37 | ||
| Type: protein-coding gene | Cytoband: 15q23 | ||
| Entrez ID: 10002 | HGNC ID: HGNC:7974 | Ensembl Gene: ENSG00000278570 | OMIM ID: 604485 |
| Drug and gene relationship at DGIdb | |||
Expression of NR2E3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | NR2E3 | 10002 | 208385_at | 0.0574 | 0.8175 | |
| GSE20347 | NR2E3 | 10002 | 208385_at | 0.0395 | 0.6657 | |
| GSE23400 | NR2E3 | 10002 | 208385_at | -0.2225 | 0.0000 | |
| GSE26886 | NR2E3 | 10002 | 208385_at | 0.2800 | 0.0253 | |
| GSE29001 | NR2E3 | 10002 | 208385_at | 0.0097 | 0.9576 | |
| GSE38129 | NR2E3 | 10002 | 208385_at | -0.0606 | 0.5992 | |
| GSE45670 | NR2E3 | 10002 | 208385_at | 0.0783 | 0.5182 | |
| GSE53622 | NR2E3 | 10002 | 13583 | -0.0235 | 0.7058 | |
| GSE53624 | NR2E3 | 10002 | 13583 | -0.2775 | 0.0000 | |
| GSE63941 | NR2E3 | 10002 | 208385_at | 0.0492 | 0.7554 | |
| GSE77861 | NR2E3 | 10002 | 208385_at | -0.0218 | 0.8255 | |
| SRP133303 | NR2E3 | 10002 | RNAseq | -0.7558 | 0.0117 | |
| SRP159526 | NR2E3 | 10002 | RNAseq | -1.6144 | 0.0029 | |
| SRP219564 | NR2E3 | 10002 | RNAseq | -0.7410 | 0.3697 | |
| TCGA | NR2E3 | 10002 | RNAseq | -1.6762 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 2.
Survival by NR2E3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of NR2E3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | NR2E3 | 10002 | 7 | 1 | 22 | |
| GSE20123 | NR2E3 | 10002 | 7 | 1 | 22 | |
| GSE43470 | NR2E3 | 10002 | 4 | 6 | 33 | |
| GSE46452 | NR2E3 | 10002 | 3 | 7 | 49 | |
| GSE47630 | NR2E3 | 10002 | 8 | 10 | 22 | |
| GSE54993 | NR2E3 | 10002 | 5 | 6 | 59 | |
| GSE54994 | NR2E3 | 10002 | 5 | 8 | 40 | |
| GSE60625 | NR2E3 | 10002 | 4 | 4 | 3 | |
| GSE74703 | NR2E3 | 10002 | 4 | 3 | 29 | |
| GSE74704 | NR2E3 | 10002 | 3 | 1 | 16 | |
| TCGA | NR2E3 | 10002 | 10 | 17 | 69 |
Total number of gains: 60; Total number of losses: 64; Total Number of normals: 364.
Somatic mutations of NR2E3:
Generating mutation plots.
Highly correlated genes for NR2E3:
Showing top 20/876 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| NR2E3 | SARDH | 0.726495 | 4 | 0 | 4 |
| NR2E3 | MSI1 | 0.689406 | 4 | 0 | 4 |
| NR2E3 | EPO | 0.684407 | 5 | 0 | 4 |
| NR2E3 | S100A1 | 0.683839 | 4 | 0 | 3 |
| NR2E3 | DAB1 | 0.68211 | 6 | 0 | 6 |
| NR2E3 | RAD52 | 0.677827 | 3 | 0 | 3 |
| NR2E3 | CCDC30 | 0.677613 | 4 | 0 | 3 |
| NR2E3 | NCR1 | 0.676657 | 4 | 0 | 4 |
| NR2E3 | SLC6A11 | 0.675019 | 3 | 0 | 3 |
| NR2E3 | OR10H3 | 0.674003 | 4 | 0 | 4 |
| NR2E3 | DAGLA | 0.670171 | 5 | 0 | 4 |
| NR2E3 | SLC6A5 | 0.666218 | 5 | 0 | 4 |
| NR2E3 | KCNQ1DN | 0.665291 | 6 | 0 | 5 |
| NR2E3 | IL19 | 0.664081 | 3 | 0 | 3 |
| NR2E3 | BLK | 0.66312 | 4 | 0 | 4 |
| NR2E3 | IL9 | 0.659784 | 3 | 0 | 3 |
| NR2E3 | LGALS14 | 0.659015 | 4 | 0 | 3 |
| NR2E3 | JAK3 | 0.656565 | 5 | 0 | 4 |
| NR2E3 | IBA57 | 0.655094 | 5 | 0 | 4 |
| NR2E3 | AMELY | 0.654381 | 4 | 0 | 3 |
For details and further investigation, click here
