| Full name: tubulin gamma complex associated protein 5 | Alias Symbol: GCP5|KIAA1899 | ||
| Type: protein-coding gene | Cytoband: 15q11.2 | ||
| Entrez ID: 114791 | HGNC ID: HGNC:18600 | Ensembl Gene: ENSG00000275835 | OMIM ID: 608147 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
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Expression of TUBGCP5:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TUBGCP5 | 114791 | 214876_s_at | 0.3027 | 0.7961 | |
| GSE20347 | TUBGCP5 | 114791 | 214876_s_at | 0.2097 | 0.0950 | |
| GSE23400 | TUBGCP5 | 114791 | 214876_s_at | 0.1635 | 0.0000 | |
| GSE26886 | TUBGCP5 | 114791 | 227967_at | 1.1138 | 0.0000 | |
| GSE29001 | TUBGCP5 | 114791 | 214876_s_at | 0.3386 | 0.0949 | |
| GSE38129 | TUBGCP5 | 114791 | 214876_s_at | 0.2683 | 0.0160 | |
| GSE45670 | TUBGCP5 | 114791 | 227967_at | 0.0093 | 0.9658 | |
| GSE53622 | TUBGCP5 | 114791 | 83563 | 0.0729 | 0.3552 | |
| GSE53624 | TUBGCP5 | 114791 | 83563 | 0.1238 | 0.1555 | |
| GSE63941 | TUBGCP5 | 114791 | 227967_at | -0.2151 | 0.6417 | |
| GSE77861 | TUBGCP5 | 114791 | 227967_at | 0.0595 | 0.7203 | |
| GSE97050 | TUBGCP5 | 114791 | A_23_P152038 | 0.0575 | 0.8073 | |
| SRP007169 | TUBGCP5 | 114791 | RNAseq | 0.0706 | 0.8715 | |
| SRP008496 | TUBGCP5 | 114791 | RNAseq | -0.1467 | 0.6423 | |
| SRP064894 | TUBGCP5 | 114791 | RNAseq | 0.1712 | 0.4404 | |
| SRP133303 | TUBGCP5 | 114791 | RNAseq | 0.1516 | 0.2094 | |
| SRP159526 | TUBGCP5 | 114791 | RNAseq | -0.0460 | 0.8507 | |
| SRP193095 | TUBGCP5 | 114791 | RNAseq | 0.1963 | 0.0700 | |
| SRP219564 | TUBGCP5 | 114791 | RNAseq | 0.1071 | 0.7272 | |
| TCGA | TUBGCP5 | 114791 | RNAseq | 0.0486 | 0.3863 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by TUBGCP5 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TUBGCP5:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TUBGCP5 | 114791 | 4 | 4 | 22 | |
| GSE20123 | TUBGCP5 | 114791 | 3 | 4 | 23 | |
| GSE43470 | TUBGCP5 | 114791 | 2 | 5 | 36 | |
| GSE46452 | TUBGCP5 | 114791 | 3 | 7 | 49 | |
| GSE47630 | TUBGCP5 | 114791 | 8 | 11 | 21 | |
| GSE54993 | TUBGCP5 | 114791 | 4 | 6 | 60 | |
| GSE54994 | TUBGCP5 | 114791 | 6 | 6 | 41 | |
| GSE60625 | TUBGCP5 | 114791 | 4 | 3 | 4 | |
| GSE74703 | TUBGCP5 | 114791 | 2 | 3 | 31 | |
| GSE74704 | TUBGCP5 | 114791 | 2 | 3 | 15 | |
| TCGA | TUBGCP5 | 114791 | 18 | 19 | 59 |
Total number of gains: 56; Total number of losses: 71; Total Number of normals: 361.
Somatic mutations of TUBGCP5:
Generating mutation plots.
Highly correlated genes for TUBGCP5:
Showing top 20/190 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TUBGCP5 | PPP1R35 | 0.704168 | 3 | 0 | 3 |
| TUBGCP5 | TXNRD1 | 0.691518 | 3 | 0 | 3 |
| TUBGCP5 | CHST7 | 0.689785 | 3 | 0 | 3 |
| TUBGCP5 | TMEM44 | 0.67145 | 3 | 0 | 3 |
| TUBGCP5 | TRIB2 | 0.667284 | 3 | 0 | 3 |
| TUBGCP5 | IREB2 | 0.658358 | 3 | 0 | 3 |
| TUBGCP5 | VMA21 | 0.656345 | 3 | 0 | 3 |
| TUBGCP5 | SFT2D3 | 0.651129 | 3 | 0 | 3 |
| TUBGCP5 | DDX60 | 0.646135 | 4 | 0 | 3 |
| TUBGCP5 | MIEN1 | 0.644194 | 3 | 0 | 3 |
| TUBGCP5 | NIPA2 | 0.64079 | 11 | 0 | 9 |
| TUBGCP5 | PHLDB2 | 0.629691 | 3 | 0 | 3 |
| TUBGCP5 | HDDC3 | 0.620403 | 3 | 0 | 3 |
| TUBGCP5 | TYW1 | 0.615846 | 3 | 0 | 3 |
| TUBGCP5 | UGGT2 | 0.614314 | 3 | 0 | 3 |
| TUBGCP5 | WRN | 0.612251 | 4 | 0 | 3 |
| TUBGCP5 | UHRF1BP1L | 0.608564 | 4 | 0 | 4 |
| TUBGCP5 | NECAP1 | 0.603264 | 5 | 0 | 3 |
| TUBGCP5 | STK32B | 0.602181 | 3 | 0 | 3 |
| TUBGCP5 | LOXL4 | 0.60156 | 4 | 0 | 3 |
For details and further investigation, click here
