| Full name: NECAP endocytosis associated 1 | Alias Symbol: DKFZP566B183 | ||
| Type: protein-coding gene | Cytoband: 12p13.31 | ||
| Entrez ID: 25977 | HGNC ID: HGNC:24539 | Ensembl Gene: ENSG00000089818 | OMIM ID: 611623 |
| Drug and gene relationship at DGIdb | |||
Expression of NECAP1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | NECAP1 | 25977 | 209300_s_at | 0.2425 | 0.4703 | |
| GSE20347 | NECAP1 | 25977 | 209300_s_at | 0.1006 | 0.6683 | |
| GSE23400 | NECAP1 | 25977 | 209300_s_at | 0.2017 | 0.0048 | |
| GSE26886 | NECAP1 | 25977 | 209300_s_at | -0.3470 | 0.2759 | |
| GSE29001 | NECAP1 | 25977 | 209300_s_at | 0.4083 | 0.0587 | |
| GSE38129 | NECAP1 | 25977 | 209300_s_at | 0.1393 | 0.3359 | |
| GSE45670 | NECAP1 | 25977 | 209300_s_at | 0.3355 | 0.0080 | |
| GSE53622 | NECAP1 | 25977 | 157910 | 0.0896 | 0.2884 | |
| GSE53624 | NECAP1 | 25977 | 157910 | 0.1363 | 0.1603 | |
| GSE63941 | NECAP1 | 25977 | 209300_s_at | -0.4877 | 0.2814 | |
| GSE77861 | NECAP1 | 25977 | 209300_s_at | 0.4515 | 0.3241 | |
| GSE97050 | NECAP1 | 25977 | A_33_P3247629 | 0.3675 | 0.2411 | |
| SRP007169 | NECAP1 | 25977 | RNAseq | 1.7578 | 0.0158 | |
| SRP008496 | NECAP1 | 25977 | RNAseq | 1.6630 | 0.0022 | |
| SRP064894 | NECAP1 | 25977 | RNAseq | -0.1391 | 0.4159 | |
| SRP133303 | NECAP1 | 25977 | RNAseq | 0.4878 | 0.0077 | |
| SRP159526 | NECAP1 | 25977 | RNAseq | -0.0908 | 0.6775 | |
| SRP193095 | NECAP1 | 25977 | RNAseq | -0.0933 | 0.3904 | |
| SRP219564 | NECAP1 | 25977 | RNAseq | 0.2571 | 0.3901 | |
| TCGA | NECAP1 | 25977 | RNAseq | -0.1265 | 0.0161 |
Upregulated datasets: 2; Downregulated datasets: 0.
Survival by NECAP1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of NECAP1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | NECAP1 | 25977 | 6 | 3 | 21 | |
| GSE20123 | NECAP1 | 25977 | 6 | 3 | 21 | |
| GSE43470 | NECAP1 | 25977 | 7 | 3 | 33 | |
| GSE46452 | NECAP1 | 25977 | 10 | 1 | 48 | |
| GSE47630 | NECAP1 | 25977 | 12 | 2 | 26 | |
| GSE54993 | NECAP1 | 25977 | 1 | 10 | 59 | |
| GSE54994 | NECAP1 | 25977 | 8 | 3 | 42 | |
| GSE60625 | NECAP1 | 25977 | 0 | 1 | 10 | |
| GSE74703 | NECAP1 | 25977 | 7 | 2 | 27 | |
| GSE74704 | NECAP1 | 25977 | 4 | 2 | 14 | |
| TCGA | NECAP1 | 25977 | 40 | 6 | 50 |
Total number of gains: 101; Total number of losses: 36; Total Number of normals: 351.
Somatic mutations of NECAP1:
Generating mutation plots.
Highly correlated genes for NECAP1:
Showing top 20/461 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| NECAP1 | TERF2 | 0.776932 | 3 | 0 | 3 |
| NECAP1 | TAS2R19 | 0.758755 | 3 | 0 | 3 |
| NECAP1 | EIF2B5 | 0.753477 | 3 | 0 | 3 |
| NECAP1 | GPD2 | 0.742152 | 3 | 0 | 3 |
| NECAP1 | RLIM | 0.738152 | 3 | 0 | 3 |
| NECAP1 | AP2M1 | 0.736401 | 3 | 0 | 3 |
| NECAP1 | LOXL4 | 0.725134 | 3 | 0 | 3 |
| NECAP1 | GPX1 | 0.721654 | 3 | 0 | 3 |
| NECAP1 | PRMT6 | 0.719513 | 3 | 0 | 3 |
| NECAP1 | DNAJB11 | 0.715506 | 3 | 0 | 3 |
| NECAP1 | ZC3H18 | 0.708277 | 3 | 0 | 3 |
| NECAP1 | PPIP5K2 | 0.705309 | 3 | 0 | 3 |
| NECAP1 | FAM168B | 0.705286 | 3 | 0 | 3 |
| NECAP1 | ACRBP | 0.70336 | 3 | 0 | 3 |
| NECAP1 | LSM10 | 0.699955 | 3 | 0 | 3 |
| NECAP1 | XPR1 | 0.699083 | 3 | 0 | 3 |
| NECAP1 | WIZ | 0.695931 | 3 | 0 | 3 |
| NECAP1 | TNFAIP8 | 0.68807 | 3 | 0 | 3 |
| NECAP1 | RPS19BP1 | 0.687433 | 3 | 0 | 3 |
| NECAP1 | PSMD13 | 0.68637 | 3 | 0 | 3 |
For details and further investigation, click here
