| Full name: thioredoxin domain containing 15 | Alias Symbol: 2310047H23Rik|FLJ22625 | ||
| Type: protein-coding gene | Cytoband: 5q31.1 | ||
| Entrez ID: 79770 | HGNC ID: HGNC:20652 | Ensembl Gene: ENSG00000113621 | OMIM ID: 617778 |
| Drug and gene relationship at DGIdb | |||
Expression of TXNDC15:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TXNDC15 | 79770 | 220495_s_at | -0.3446 | 0.4882 | |
| GSE20347 | TXNDC15 | 79770 | 220495_s_at | 0.1886 | 0.3464 | |
| GSE23400 | TXNDC15 | 79770 | 220495_s_at | 0.3670 | 0.0000 | |
| GSE26886 | TXNDC15 | 79770 | 220495_s_at | 0.3426 | 0.1346 | |
| GSE29001 | TXNDC15 | 79770 | 220495_s_at | 0.2760 | 0.2821 | |
| GSE38129 | TXNDC15 | 79770 | 220495_s_at | 0.2260 | 0.1925 | |
| GSE45670 | TXNDC15 | 79770 | 220495_s_at | -0.0862 | 0.7562 | |
| GSE53622 | TXNDC15 | 79770 | 137875 | 0.0388 | 0.6555 | |
| GSE53624 | TXNDC15 | 79770 | 137875 | 0.1492 | 0.0363 | |
| GSE63941 | TXNDC15 | 79770 | 220495_s_at | -1.6391 | 0.0104 | |
| GSE77861 | TXNDC15 | 79770 | 220495_s_at | 0.0025 | 0.9931 | |
| GSE97050 | TXNDC15 | 79770 | A_33_P3313030 | -0.0086 | 0.9808 | |
| SRP007169 | TXNDC15 | 79770 | RNAseq | 0.4926 | 0.2306 | |
| SRP008496 | TXNDC15 | 79770 | RNAseq | 0.8859 | 0.0012 | |
| SRP064894 | TXNDC15 | 79770 | RNAseq | 0.1758 | 0.3072 | |
| SRP133303 | TXNDC15 | 79770 | RNAseq | 0.2602 | 0.1004 | |
| SRP159526 | TXNDC15 | 79770 | RNAseq | 0.3594 | 0.2234 | |
| SRP193095 | TXNDC15 | 79770 | RNAseq | 0.0721 | 0.4573 | |
| SRP219564 | TXNDC15 | 79770 | RNAseq | 0.1882 | 0.6443 | |
| TCGA | TXNDC15 | 79770 | RNAseq | -0.2062 | 0.0001 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by TXNDC15 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TXNDC15:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TXNDC15 | 79770 | 3 | 11 | 16 | |
| GSE20123 | TXNDC15 | 79770 | 4 | 11 | 15 | |
| GSE43470 | TXNDC15 | 79770 | 4 | 6 | 33 | |
| GSE46452 | TXNDC15 | 79770 | 0 | 27 | 32 | |
| GSE47630 | TXNDC15 | 79770 | 0 | 21 | 19 | |
| GSE54993 | TXNDC15 | 79770 | 9 | 1 | 60 | |
| GSE54994 | TXNDC15 | 79770 | 3 | 13 | 37 | |
| GSE60625 | TXNDC15 | 79770 | 0 | 0 | 11 | |
| GSE74703 | TXNDC15 | 79770 | 3 | 4 | 29 | |
| GSE74704 | TXNDC15 | 79770 | 3 | 5 | 12 | |
| TCGA | TXNDC15 | 79770 | 3 | 36 | 57 |
Total number of gains: 32; Total number of losses: 135; Total Number of normals: 321.
Somatic mutations of TXNDC15:
Generating mutation plots.
Highly correlated genes for TXNDC15:
Showing top 20/466 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TXNDC15 | IGBP1 | 0.772796 | 3 | 0 | 3 |
| TXNDC15 | C11orf96 | 0.729478 | 3 | 0 | 3 |
| TXNDC15 | GNG12 | 0.712672 | 3 | 0 | 3 |
| TXNDC15 | UBE2Q2 | 0.711571 | 3 | 0 | 3 |
| TXNDC15 | TNFRSF19 | 0.673539 | 3 | 0 | 3 |
| TXNDC15 | THAP8 | 0.672115 | 4 | 0 | 3 |
| TXNDC15 | SPAG7 | 0.666349 | 3 | 0 | 3 |
| TXNDC15 | RELL1 | 0.66608 | 3 | 0 | 3 |
| TXNDC15 | WFDC1 | 0.661129 | 4 | 0 | 3 |
| TXNDC15 | ZNF25 | 0.655761 | 6 | 0 | 6 |
| TXNDC15 | GNG2 | 0.651083 | 4 | 0 | 4 |
| TXNDC15 | GLIS2 | 0.65098 | 3 | 0 | 3 |
| TXNDC15 | ATG12 | 0.649912 | 5 | 0 | 4 |
| TXNDC15 | RHOBTB2 | 0.64926 | 3 | 0 | 3 |
| TXNDC15 | DNM3 | 0.645069 | 4 | 0 | 4 |
| TXNDC15 | NDUFA2 | 0.639662 | 3 | 0 | 3 |
| TXNDC15 | EGFLAM | 0.639328 | 4 | 0 | 3 |
| TXNDC15 | STX8 | 0.636369 | 3 | 0 | 3 |
| TXNDC15 | PEG3 | 0.636137 | 3 | 0 | 3 |
| TXNDC15 | TNFSF12 | 0.635962 | 3 | 0 | 3 |
For details and further investigation, click here
