| Full name: suppressor of variegation 3-9 homolog 2 | Alias Symbol: FLJ23414|KMT1B | ||
| Type: protein-coding gene | Cytoband: 10p13 | ||
| Entrez ID: 79723 | HGNC ID: HGNC:17287 | Ensembl Gene: ENSG00000152455 | OMIM ID: 606503 |
| Drug and gene relationship at DGIdb | |||
Expression of SUV39H2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SUV39H2 | 79723 | 1554572_a_at | 0.8034 | 0.0502 | |
| GSE20347 | SUV39H2 | 79723 | 219262_at | -0.0219 | 0.7745 | |
| GSE23400 | SUV39H2 | 79723 | 219262_at | -0.0408 | 0.0182 | |
| GSE26886 | SUV39H2 | 79723 | 1554572_a_at | 0.5567 | 0.0135 | |
| GSE29001 | SUV39H2 | 79723 | 219262_at | 0.0721 | 0.6854 | |
| GSE38129 | SUV39H2 | 79723 | 219262_at | 0.0792 | 0.3209 | |
| GSE45670 | SUV39H2 | 79723 | 1554572_a_at | 0.5223 | 0.0079 | |
| GSE53622 | SUV39H2 | 79723 | 126654 | 0.5112 | 0.0000 | |
| GSE53624 | SUV39H2 | 79723 | 126654 | 0.6280 | 0.0000 | |
| GSE63941 | SUV39H2 | 79723 | 1554572_a_at | 1.3055 | 0.0052 | |
| GSE77861 | SUV39H2 | 79723 | 1554572_a_at | 0.2928 | 0.2314 | |
| GSE97050 | SUV39H2 | 79723 | A_23_P202392 | 0.6783 | 0.1854 | |
| SRP007169 | SUV39H2 | 79723 | RNAseq | 1.3082 | 0.0149 | |
| SRP008496 | SUV39H2 | 79723 | RNAseq | 1.1567 | 0.0031 | |
| SRP064894 | SUV39H2 | 79723 | RNAseq | 0.1888 | 0.2565 | |
| SRP133303 | SUV39H2 | 79723 | RNAseq | 0.1325 | 0.3230 | |
| SRP159526 | SUV39H2 | 79723 | RNAseq | 0.4979 | 0.1450 | |
| SRP193095 | SUV39H2 | 79723 | RNAseq | 0.0603 | 0.5624 | |
| SRP219564 | SUV39H2 | 79723 | RNAseq | 0.2500 | 0.4883 | |
| TCGA | SUV39H2 | 79723 | RNAseq | 0.3020 | 0.0000 |
Upregulated datasets: 3; Downregulated datasets: 0.
Survival by SUV39H2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SUV39H2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SUV39H2 | 79723 | 3 | 8 | 19 | |
| GSE20123 | SUV39H2 | 79723 | 3 | 7 | 20 | |
| GSE43470 | SUV39H2 | 79723 | 3 | 5 | 35 | |
| GSE46452 | SUV39H2 | 79723 | 1 | 14 | 44 | |
| GSE47630 | SUV39H2 | 79723 | 5 | 15 | 20 | |
| GSE54993 | SUV39H2 | 79723 | 10 | 0 | 60 | |
| GSE54994 | SUV39H2 | 79723 | 4 | 9 | 40 | |
| GSE60625 | SUV39H2 | 79723 | 0 | 0 | 11 | |
| GSE74703 | SUV39H2 | 79723 | 2 | 3 | 31 | |
| GSE74704 | SUV39H2 | 79723 | 0 | 6 | 14 | |
| TCGA | SUV39H2 | 79723 | 20 | 25 | 51 |
Total number of gains: 51; Total number of losses: 92; Total Number of normals: 345.
Somatic mutations of SUV39H2:
Generating mutation plots.
Highly correlated genes for SUV39H2:
Showing top 20/369 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SUV39H2 | EME1 | 0.699126 | 4 | 0 | 4 |
| SUV39H2 | HMCES | 0.689555 | 5 | 0 | 5 |
| SUV39H2 | COA7 | 0.687478 | 4 | 0 | 4 |
| SUV39H2 | CDCA2 | 0.681262 | 4 | 0 | 3 |
| SUV39H2 | HAUS8 | 0.681107 | 7 | 0 | 6 |
| SUV39H2 | BEND3 | 0.673186 | 7 | 0 | 6 |
| SUV39H2 | ECT2 | 0.670901 | 9 | 0 | 8 |
| SUV39H2 | FEN1 | 0.669384 | 6 | 0 | 5 |
| SUV39H2 | SPC25 | 0.669125 | 9 | 0 | 8 |
| SUV39H2 | MCM5 | 0.663927 | 6 | 0 | 6 |
| SUV39H2 | HOXA10 | 0.663567 | 3 | 0 | 3 |
| SUV39H2 | BLM | 0.663355 | 7 | 0 | 7 |
| SUV39H2 | PKMYT1 | 0.661956 | 3 | 0 | 3 |
| SUV39H2 | E2F7 | 0.660726 | 7 | 0 | 6 |
| SUV39H2 | TMEM223 | 0.659365 | 3 | 0 | 3 |
| SUV39H2 | CCDC34 | 0.657311 | 8 | 0 | 7 |
| SUV39H2 | EXO1 | 0.650405 | 10 | 0 | 8 |
| SUV39H2 | CDCA8 | 0.650301 | 7 | 0 | 6 |
| SUV39H2 | PBK | 0.64991 | 7 | 0 | 6 |
| SUV39H2 | PUS1 | 0.649794 | 6 | 0 | 5 |
For details and further investigation, click here
