| Full name: AAR2 splicing factor | Alias Symbol: bA234K24.2 | ||
| Type: protein-coding gene | Cytoband: 20q11.23 | ||
| Entrez ID: 25980 | HGNC ID: HGNC:15886 | Ensembl Gene: ENSG00000131043 | OMIM ID: 617365 |
| Drug and gene relationship at DGIdb | |||
Expression of AAR2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | AAR2 | 25980 | 218089_at | 0.5179 | 0.1097 | |
| GSE20347 | AAR2 | 25980 | 218089_at | 0.4431 | 0.0001 | |
| GSE23400 | AAR2 | 25980 | 218089_at | 0.0840 | 0.0335 | |
| GSE26886 | AAR2 | 25980 | 218089_at | 0.5799 | 0.0030 | |
| GSE29001 | AAR2 | 25980 | 218089_at | 0.3881 | 0.0017 | |
| GSE38129 | AAR2 | 25980 | 218089_at | 0.2551 | 0.0160 | |
| GSE45670 | AAR2 | 25980 | 218089_at | 0.1725 | 0.1508 | |
| GSE53622 | AAR2 | 25980 | 32406 | -0.0191 | 0.8165 | |
| GSE53624 | AAR2 | 25980 | 32406 | -0.0375 | 0.7114 | |
| GSE63941 | AAR2 | 25980 | 218089_at | 0.2746 | 0.4944 | |
| GSE77861 | AAR2 | 25980 | 218089_at | 0.2558 | 0.0698 | |
| SRP007169 | AAR2 | 25980 | RNAseq | 1.2201 | 0.0298 | |
| SRP008496 | AAR2 | 25980 | RNAseq | 1.2002 | 0.0021 | |
| SRP064894 | AAR2 | 25980 | RNAseq | 0.5577 | 0.0071 | |
| SRP133303 | AAR2 | 25980 | RNAseq | 0.4633 | 0.0001 | |
| SRP159526 | AAR2 | 25980 | RNAseq | 0.2295 | 0.2895 | |
| SRP193095 | AAR2 | 25980 | RNAseq | 0.4348 | 0.0000 | |
| SRP219564 | AAR2 | 25980 | RNAseq | 0.1173 | 0.7667 |
Upregulated datasets: 2; Downregulated datasets: 0.
Survival by AAR2 expression:
 |  |
| GSE53622 | GSE53624 |
Note: Click image to view full size file.
Copy number change of AAR2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | AAR2 | 25980 | 14 | 1 | 15 | |
| GSE20123 | AAR2 | 25980 | 14 | 1 | 15 | |
| GSE43470 | AAR2 | 25980 | 12 | 0 | 31 | |
| GSE46452 | AAR2 | 25980 | 29 | 0 | 30 | |
| GSE47630 | AAR2 | 25980 | 24 | 0 | 16 | |
| GSE54993 | AAR2 | 25980 | 0 | 17 | 53 | |
| GSE54994 | AAR2 | 25980 | 24 | 0 | 29 | |
| GSE60625 | AAR2 | 25980 | 0 | 0 | 11 | |
| GSE74703 | AAR2 | 25980 | 11 | 0 | 25 | |
| GSE74704 | AAR2 | 25980 | 10 | 0 | 10 | |
| TCGA | AAR2 | 25980 | 49 | 4 | 43 |
Total number of gains: 187; Total number of losses: 23; Total Number of normals: 278.
Somatic mutations of AAR2:
Generating mutation plots.
Highly correlated genes for AAR2:
Showing top 20/860 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| AAR2 | RPRD1B | 0.800582 | 3 | 0 | 3 |
| AAR2 | XRN2 | 0.740722 | 3 | 0 | 3 |
| AAR2 | SIMC1 | 0.726503 | 3 | 0 | 3 |
| AAR2 | FBXO5 | 0.711207 | 3 | 0 | 3 |
| AAR2 | RAD54L | 0.701292 | 3 | 0 | 3 |
| AAR2 | SDCCAG8 | 0.693606 | 3 | 0 | 3 |
| AAR2 | ZNFX1 | 0.685522 | 4 | 0 | 3 |
| AAR2 | PYGB | 0.678868 | 3 | 0 | 3 |
| AAR2 | PALB2 | 0.678606 | 3 | 0 | 3 |
| AAR2 | SLC8B1 | 0.676671 | 3 | 0 | 3 |
| AAR2 | APMAP | 0.664295 | 7 | 0 | 7 |
| AAR2 | PLOD3 | 0.663984 | 7 | 0 | 6 |
| AAR2 | CKS2 | 0.663919 | 4 | 0 | 4 |
| AAR2 | HPS3 | 0.663371 | 3 | 0 | 3 |
| AAR2 | YTHDF1 | 0.663239 | 8 | 0 | 7 |
| AAR2 | CENPBD1 | 0.662436 | 4 | 0 | 4 |
| AAR2 | ASXL1 | 0.657077 | 6 | 0 | 5 |
| AAR2 | PIGT | 0.657075 | 8 | 0 | 6 |
| AAR2 | LAMB3 | 0.656577 | 5 | 0 | 4 |
| AAR2 | EFTUD2 | 0.656363 | 4 | 0 | 4 |
For details and further investigation, click here
