| Full name: ADAM metallopeptidase with thrombospondin type 1 motif 9 | Alias Symbol: KIAA1312 | ||
| Type: protein-coding gene | Cytoband: 3p14.1 | ||
| Entrez ID: 56999 | HGNC ID: HGNC:13202 | Ensembl Gene: ENSG00000163638 | OMIM ID: 605421 |
| Drug and gene relationship at DGIdb | |||
Expression of ADAMTS9:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ADAMTS9 | 56999 | 226814_at | -0.2593 | 0.7151 | |
| GSE20347 | ADAMTS9 | 56999 | 220287_at | -0.1270 | 0.4718 | |
| GSE23400 | ADAMTS9 | 56999 | 220287_at | -0.3401 | 0.0002 | |
| GSE26886 | ADAMTS9 | 56999 | 233785_at | -0.4745 | 0.0019 | |
| GSE29001 | ADAMTS9 | 56999 | 220287_at | -0.1034 | 0.7262 | |
| GSE38129 | ADAMTS9 | 56999 | 220287_at | -0.3161 | 0.1884 | |
| GSE45670 | ADAMTS9 | 56999 | 226814_at | -0.4552 | 0.3321 | |
| GSE53622 | ADAMTS9 | 56999 | 109410 | 0.0634 | 0.7944 | |
| GSE53624 | ADAMTS9 | 56999 | 109410 | 0.2305 | 0.2146 | |
| GSE63941 | ADAMTS9 | 56999 | 226814_at | -3.0793 | 0.0000 | |
| GSE77861 | ADAMTS9 | 56999 | 233785_at | -0.0269 | 0.7521 | |
| GSE97050 | ADAMTS9 | 56999 | A_32_P196263 | 0.4097 | 0.3303 | |
| SRP007169 | ADAMTS9 | 56999 | RNAseq | 1.9843 | 0.0033 | |
| SRP064894 | ADAMTS9 | 56999 | RNAseq | 0.6002 | 0.2320 | |
| SRP133303 | ADAMTS9 | 56999 | RNAseq | -0.4267 | 0.2464 | |
| SRP159526 | ADAMTS9 | 56999 | RNAseq | 1.1879 | 0.0863 | |
| SRP193095 | ADAMTS9 | 56999 | RNAseq | 1.4798 | 0.0000 | |
| SRP219564 | ADAMTS9 | 56999 | RNAseq | -0.0548 | 0.9359 | |
| TCGA | ADAMTS9 | 56999 | RNAseq | -0.6127 | 0.0001 |
Upregulated datasets: 2; Downregulated datasets: 1.
Survival by ADAMTS9 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ADAMTS9:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ADAMTS9 | 56999 | 0 | 17 | 13 | |
| GSE20123 | ADAMTS9 | 56999 | 0 | 18 | 12 | |
| GSE43470 | ADAMTS9 | 56999 | 0 | 19 | 24 | |
| GSE46452 | ADAMTS9 | 56999 | 2 | 17 | 40 | |
| GSE47630 | ADAMTS9 | 56999 | 1 | 24 | 15 | |
| GSE54993 | ADAMTS9 | 56999 | 5 | 2 | 63 | |
| GSE54994 | ADAMTS9 | 56999 | 1 | 33 | 19 | |
| GSE60625 | ADAMTS9 | 56999 | 3 | 1 | 7 | |
| GSE74703 | ADAMTS9 | 56999 | 0 | 15 | 21 | |
| GSE74704 | ADAMTS9 | 56999 | 0 | 12 | 8 | |
| TCGA | ADAMTS9 | 56999 | 0 | 77 | 19 |
Total number of gains: 12; Total number of losses: 235; Total Number of normals: 241.
Somatic mutations of ADAMTS9:
Generating mutation plots.
Highly correlated genes for ADAMTS9:
Showing top 20/274 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ADAMTS9 | ZNF578 | 0.744524 | 3 | 0 | 3 |
| ADAMTS9 | UBAP1 | 0.741226 | 3 | 0 | 3 |
| ADAMTS9 | CNR1 | 0.729675 | 3 | 0 | 3 |
| ADAMTS9 | SLC30A5 | 0.728168 | 3 | 0 | 3 |
| ADAMTS9 | AFF3 | 0.714227 | 3 | 0 | 3 |
| ADAMTS9 | PPM1D | 0.70619 | 3 | 0 | 3 |
| ADAMTS9 | TAS2R4 | 0.69545 | 3 | 0 | 3 |
| ADAMTS9 | ENG | 0.695197 | 6 | 0 | 5 |
| ADAMTS9 | PPP3CC | 0.688446 | 3 | 0 | 3 |
| ADAMTS9 | PRADC1 | 0.676386 | 3 | 0 | 3 |
| ADAMTS9 | LINC00473 | 0.674355 | 3 | 0 | 3 |
| ADAMTS9 | COL15A1 | 0.672956 | 7 | 0 | 6 |
| ADAMTS9 | TRPV2 | 0.671522 | 4 | 0 | 3 |
| ADAMTS9 | CHL1 | 0.67019 | 4 | 0 | 4 |
| ADAMTS9 | CECR9 | 0.667066 | 3 | 0 | 3 |
| ADAMTS9 | CYP4V2 | 0.664562 | 3 | 0 | 3 |
| ADAMTS9 | ERCC4 | 0.663699 | 3 | 0 | 3 |
| ADAMTS9 | KIAA0355 | 0.663291 | 3 | 0 | 3 |
| ADAMTS9 | UBR4 | 0.660742 | 3 | 0 | 3 |
| ADAMTS9 | TMEM120A | 0.660469 | 3 | 0 | 3 |
For details and further investigation, click here
