| Full name: praja ring finger ubiquitin ligase 2 | Alias Symbol: KIAA0438|Neurodap1 | ||
| Type: protein-coding gene | Cytoband: 5q21.3 | ||
| Entrez ID: 9867 | HGNC ID: HGNC:17481 | Ensembl Gene: ENSG00000198961 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of PJA2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PJA2 | 9867 | 201133_s_at | -0.7293 | 0.1570 | |
| GSE20347 | PJA2 | 9867 | 201133_s_at | -0.4497 | 0.0042 | |
| GSE23400 | PJA2 | 9867 | 201133_s_at | -0.3824 | 0.0045 | |
| GSE26886 | PJA2 | 9867 | 201133_s_at | -1.2221 | 0.0000 | |
| GSE29001 | PJA2 | 9867 | 201133_s_at | -0.3817 | 0.1898 | |
| GSE38129 | PJA2 | 9867 | 201133_s_at | -0.7123 | 0.0000 | |
| GSE45670 | PJA2 | 9867 | 201133_s_at | -0.5860 | 0.0001 | |
| GSE53622 | PJA2 | 9867 | 52415 | -0.5536 | 0.0000 | |
| GSE53624 | PJA2 | 9867 | 8688 | -0.5514 | 0.0000 | |
| GSE63941 | PJA2 | 9867 | 201133_s_at | -1.4025 | 0.0023 | |
| GSE77861 | PJA2 | 9867 | 201133_s_at | -0.2404 | 0.6140 | |
| GSE97050 | PJA2 | 9867 | A_23_P133470 | -0.6982 | 0.1223 | |
| SRP007169 | PJA2 | 9867 | RNAseq | -0.3320 | 0.3304 | |
| SRP008496 | PJA2 | 9867 | RNAseq | -0.0880 | 0.6700 | |
| SRP064894 | PJA2 | 9867 | RNAseq | -0.4446 | 0.1081 | |
| SRP133303 | PJA2 | 9867 | RNAseq | -0.0950 | 0.6772 | |
| SRP159526 | PJA2 | 9867 | RNAseq | -0.8642 | 0.0273 | |
| SRP193095 | PJA2 | 9867 | RNAseq | -0.4457 | 0.0000 | |
| SRP219564 | PJA2 | 9867 | RNAseq | -0.5971 | 0.2757 | |
| TCGA | PJA2 | 9867 | RNAseq | -0.1791 | 0.0001 |
Upregulated datasets: 0; Downregulated datasets: 2.
Survival by PJA2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PJA2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PJA2 | 9867 | 1 | 13 | 16 | |
| GSE20123 | PJA2 | 9867 | 1 | 13 | 16 | |
| GSE43470 | PJA2 | 9867 | 3 | 8 | 32 | |
| GSE46452 | PJA2 | 9867 | 0 | 28 | 31 | |
| GSE47630 | PJA2 | 9867 | 0 | 21 | 19 | |
| GSE54993 | PJA2 | 9867 | 9 | 1 | 60 | |
| GSE54994 | PJA2 | 9867 | 1 | 17 | 35 | |
| GSE60625 | PJA2 | 9867 | 0 | 0 | 11 | |
| GSE74703 | PJA2 | 9867 | 2 | 6 | 28 | |
| GSE74704 | PJA2 | 9867 | 1 | 7 | 12 | |
| TCGA | PJA2 | 9867 | 2 | 41 | 53 |
Total number of gains: 20; Total number of losses: 155; Total Number of normals: 313.
Somatic mutations of PJA2:
Generating mutation plots.
Highly correlated genes for PJA2:
Showing top 20/959 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PJA2 | NKAPL | 0.803176 | 3 | 0 | 3 |
| PJA2 | EAF1 | 0.780959 | 3 | 0 | 3 |
| PJA2 | NSRP1 | 0.753715 | 3 | 0 | 3 |
| PJA2 | DDHD2 | 0.75182 | 3 | 0 | 3 |
| PJA2 | GNPDA2 | 0.734169 | 5 | 0 | 5 |
| PJA2 | SNX18 | 0.732017 | 3 | 0 | 3 |
| PJA2 | ZNF407 | 0.719962 | 3 | 0 | 3 |
| PJA2 | SLMAP | 0.718388 | 8 | 0 | 8 |
| PJA2 | EIF4E3 | 0.714793 | 6 | 0 | 6 |
| PJA2 | LZIC | 0.714301 | 3 | 0 | 3 |
| PJA2 | STARD9 | 0.711359 | 5 | 0 | 5 |
| PJA2 | TTC37 | 0.708806 | 10 | 0 | 9 |
| PJA2 | YAP1 | 0.705342 | 3 | 0 | 3 |
| PJA2 | PDCD4 | 0.697999 | 3 | 0 | 3 |
| PJA2 | FYCO1 | 0.692979 | 10 | 0 | 9 |
| PJA2 | LSM11 | 0.692825 | 5 | 0 | 4 |
| PJA2 | TMEM41B | 0.690056 | 3 | 0 | 3 |
| PJA2 | XKR4 | 0.685218 | 5 | 0 | 5 |
| PJA2 | PCMTD1 | 0.683277 | 4 | 0 | 4 |
| PJA2 | IL6ST | 0.682002 | 11 | 0 | 9 |
For details and further investigation, click here
